Antimalarial artemisinin analogs : synthesis of 2,3-desethano-12-deoxoartemisinin-related compounds

2,3-Desethano-12-deoxoartemisinin-related compounds ((+)-16a) and ((-)-16b) have been synthetized from R-(+)-citronellal (7) by a stereoselective manner, which is applied to the synthesis of various novel antimalarial artemisinin analogs