A Phase I trial of prolonged administration of lovastatin in patients with recurrent or metastatic squamous cell carcinoma of the head and neck or of the cervix.

[1]  S. Gruber,et al.  HMG CoA reductase inhibitors and the risk of colorectal cancer. , 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[2]  Henk-Jan Guchelaar,et al.  The risk of cancer in users of statins. , 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[3]  J. Slattery,et al.  Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). 1994. , 1994, Atherosclerosis. Supplements.

[4]  Keunchil Park,et al.  Phase II Study of High-Dose Lovastatin in Patients with Advanced Gastric Adenocarcinoma , 2004, Investigational New Drugs.

[5]  P. Bonomi Erlotinib: a new therapeutic approach for non-small cell lung cancer , 2003, Expert opinion on investigational drugs.

[6]  J. Farmer Statins and myotoxicity , 2003, Current atherosclerosis reports.

[7]  Kelvin K. W. Chan,et al.  The statins as anticancer agents. , 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

[8]  M. Minden,et al.  HMG-CoA reductase inhibitors and the malignant cell: the statin family of drugs as triggers of tumor-specific apoptosis , 2002, Leukemia.

[9]  L. Penn,et al.  Microarray and biochemical analysis of lovastatin-induced apoptosis of squamous cell carcinomas. , 2002, Neoplasia.

[10]  Y. Matsuzawa,et al.  Hepatocellular Carcinoma (hcc) Causes Death in Patients with Cirrhosis and Is One of the Most Prevalent Malignant Tumours Effect of Pravastatin on Survival in Patients with Advanced Hepatocellular Carcinoma. a Randomized Controlled Trial , 2022 .

[11]  L. Penn,et al.  Differential sensitivity of various pediatric cancers and squamous cell carcinomas to lovastatin-induced apoptosis: therapeutic implications. , 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

[12]  M. Moore,et al.  Determination of Lovastatin in Human Plasma Using Reverse-Phase High-Performance Liquid Chromatography With UV Detection , 2000, Therapeutic drug monitoring.

[13]  L. Blais,et al.  3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors and the risk of cancer: a nested case-control study. , 2000, Archives of internal medicine.

[14]  M. Minden,et al.  Lovastatin Induces a Pronounced Differentiation Response in Acute Myeloid Leukemias , 2000, Leukemia & lymphoma.

[15]  K. Overvad,et al.  Coenzyme Q10 in health and disease , 1999, European Journal of Clinical Nutrition.

[16]  B. Halmos,et al.  Lovastatin augments apoptosis induced by chemotherapeutic agents in colon cancer cells. , 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

[17]  M. Minden,et al.  Increased sensitivity of acute myeloid leukemias to lovastatin-induced apoptosis: A potential therapeutic approach. , 1999, Blood.

[18]  E. Laws,et al.  A phase I-II trial of lovastatin for anaplastic astrocytoma and glioblastoma multiforme. , 1998, American journal of clinical oncology.

[19]  C. Hennekens,et al.  Cholesterol lowering with statin drugs, risk of stroke, and total mortality. An overview of randomized trials. , 1997, JAMA.

[20]  D. Samid,et al.  Phase I study of lovastatin, an inhibitor of the mevalonate pathway, in patients with cancer. , 1996, Clinical cancer research : an official journal of the American Association for Cancer Research.

[21]  H. Yeger,et al.  HMG–CoA reductase mediates the biological effects of retinoic acid on human neuroblastoma cells: Lovastatin specifically targets P–glycoprotein–expressing cells , 1996, Nature Medicine.

[22]  A. Catapano,et al.  Pharmacology of competitive inhibitors of HMG-CoA reductase. , 1995, Pharmacological research.

[23]  T. Tong,et al.  Cancer statistics, 1994 , 1994, CA: a cancer journal for clinicians.

[24]  D. Hunninghake HMG CoA reductase inhibitors , 1992 .

[25]  K. Keyomarsi,et al.  Synchronization of tumor and normal cells from G1 to multiple cell cycles by lovastatin. , 1991, Cancer research.

[26]  J. Goldstein,et al.  Regulation of the mevalonate pathway , 1990, Nature.