The human xenobiotic‐metabolizing enzyme arylamine N‐acetyltransferase 1 (NAT1) is irreversibly inhibited by inorganic (Hg2+) and organic mercury (CH3Hg+): Mechanism and kinetics
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E. Sanfins | J. Dairou | J. Dupret | N. Ragunathan | Florent Busi | B. Pluvinage | F. Rodrigues-Lima
[1] J. Dairou,et al. Human arylamine N-acetyltransferase 1: a drug-metabolizing enzyme and a drug target? , 2010, Current Drug Targets.
[2] R. Minchin,et al. Small molecule inhibition of arylamine N-acetyltransferase Type I inhibits proliferation and invasiveness of MDA-MB-231 breast cancer cells. , 2010, Biochemical and biophysical research communications.
[3] A. Baeza-Squiban,et al. Arylamine N-acetyltransferase activity in bronchial epithelial cells and its inhibition by cellular oxidants. , 2009, Toxicology and applied pharmacology.
[4] Fernando Rodrigues-Lima,et al. Identification of the Xenobiotic-Metabolizing Enzyme Arylamine N-Acetyltransferase 1 as a New Target of Cisplatin in Breast Cancer Cells: Molecular and Cellular Mechanisms of Inhibition , 2008, Molecular Pharmacology.
[5] James Robinson,et al. Arylamine N‐acetyltransferase 1 expression in breast cancer cell lines: A potential marker in estrogen receptor‐positive tumors , 2008, Genes, chromosomes & cancer.
[6] W. Griffiths,et al. Deletion of a xenobiotic metabolizing gene in mice affects folate metabolism , 2007, Biochemical and biophysical research communications.
[7] A. Bozcaarmutlu. Mechanism of inhibition of purified leaping mullet (liza saliens) NADPH‐cytochrome P450 reductase by toxic metals: Aluminum and thallium , 2007, Journal of biochemical and molecular toxicology.
[8] Kwangsik Park,et al. Induction of reactive oxygen species and apoptosis in BEAS-2B cells by mercuric chloride. , 2007, Toxicology in vitro : an international journal published in association with BIBRA.
[9] J. Castell,et al. Metabolism and bioactivation of toxicants in the lung. The in vitro cellular approach. , 2005, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.
[10] Rudolfs K. Zalups,et al. Molecular and ionic mimicry and the transport of toxic metals. , 2005, Toxicology and applied pharmacology.
[11] F. Malecaze,et al. The Xenobiotic-Metabolizing Enzymes Arylamine N-Acetyltransferases in Human Lens Epithelial Cells: Inactivation by Cellular Oxidants and UVB-Induced Oxidative Stress , 2005, Molecular Pharmacology.
[12] G. Fakis,et al. Arylamine N-Acetyltransferases: What We Learn from Genes and Genomes , 2005, Drug metabolism reviews.
[13] K. Nuttall,et al. Interpreting mercury in blood and urine of individual patients. , 2004, Annals of clinical and laboratory science.
[14] A. Harris,et al. Arylamine N-acetyltransferase-1 is highly expressed in breast cancers and conveys enhanced growth and resistance to etoposide in vitro. , 2003, Molecular cancer research : MCR.
[15] J. Dairou,et al. Reversible inhibition of the human xenobiotic-metabolizing enzyme arylamine N-acetyltransferase 1 by S-nitrosothiols. , 2003, Biochemical and biophysical research communications.
[16] R. Cooper,et al. Skeletal Muscles Express the Xenobiotic-metabolizing Enzyme Arylamine N-acetyltransferase , 2003, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
[17] E. Sim,et al. The COOH Terminus of Arylamine N-Acetyltransferase from Salmonella typhimurium Controls Enzymic Activity* , 2002, Journal of Biological Chemistry.
[18] M. Fukuhara,et al. Comparative Study on in vitro Inhibitory Effects of Heavy Metals on Rabbit Drug-Metabolizing Enzymes , 2001 .
[19] D. Grant,et al. Pharmacogenetics of the arylamine N-acetyltransferases: a symposium in honor of Wendell W. Weber. , 2000, Drug metabolism and disposition: the biological fate of chemicals.
[20] W. MacNee,et al. Regulation of redox glutathione levels and gene transcription in lung inflammation: therapeutic approaches. , 2000, Free radical biology & medicine.
[21] B. Hammock,et al. Inhibition of soluble and microsomal epoxide hydrolase by zinc and other metals. , 1999, Toxicological sciences : an official journal of the Society of Toxicology.
[22] J. Chang,et al. Inhibition of Na(+)-K(+)-2Cl(-) cotransport by mercury. , 1999, The American journal of physiology.
[23] R. Minchin. Acetylation of p-aminobenzoylglutamate, a folic acid catabolite, by recombinant human arylamine N-acetyltransferase and U937 cells. , 1995, The Biochemical journal.
[24] D. Grant,et al. Monomorphic and polymorphic human arylamine N-acetyltransferases: a comparison of liver isozymes and expressed products of two cloned genes. , 1991, Molecular pharmacology.
[25] C. Elson,et al. Influence of mercury (II), cadmium (II), methylmercury, and phenylmercury on the kinetic properties of rat liver glutathione peroxidase. , 1985, Canadian journal of biochemistry and cell biology = Revue canadienne de biochimie et biologie cellulaire.
[26] S. Cohen,et al. N-acetylation of drugs: isolation and properties of an N-acetyltransferase from rabbit liver. , 1967, Molecular pharmacology.
[27] R. Minchin,et al. Arylamine N-acetyltransferase I. , 2007, The international journal of biochemistry & cell biology.
[28] M. Doll,et al. Molecular genetics and epidemiology of the NAT1 and NAT2 acetylation polymorphisms. , 2000, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
[29] John Doull,et al. VIRAL DISEASES: A SYMPOSIUM , 1976, The Ulster Medical Journal.