WWOX, a chromosomal fragile site gene and its role in cancer.

[1]  D. Gomes,et al.  Characterization of the tumor suppressor gene WWOX in primary human oral squamous cell carcinomas , 2006, International journal of cancer.

[2]  Q. Hong,et al.  WOX1 Is Essential for Tumor Necrosis Factor-, UV Light-, Staurosporine-, and p53-mediated Cell Death, and Its Tyrosine 33-phosphorylated Form Binds and Stabilizes Serine 46-phosphorylated p53* , 2005, Journal of Biological Chemistry.

[3]  M. Macleod,et al.  Expression of common chromosomal fragile site genes, WWOX/FRA16D and FHIT/FRA3B is downregulated by exposure to environmental carcinogens, UV, and BPDE but not by IR , 2005, Molecular carcinogenesis.

[4]  D. Amadori,et al.  WWOX gene restoration prevents lung cancer growth in vitro and in vivo , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[5]  Y. Pekarsky,et al.  WW domain-containing proteins, WWOX and YAP, compete for interaction with ErbB-4 and modulate its transcriptional function. , 2005, Cancer research.

[6]  G. Mills,et al.  WWOX protein expression varies among ovarian carcinoma histotypes and correlates with less favorable outcome , 2005, BMC Cancer.

[7]  R. Weigel,et al.  Physical and Functional Interactions between the Wwox Tumor Suppressor Protein and the AP-2γ Transcription Factor , 2004, Cancer Research.

[8]  J. Ludes-Meyers,et al.  Frequent downregulation and loss of WWOX gene expression in human hepatocellular carcinoma , 2004, British Journal of Cancer.

[9]  J. Ludes-Meyers,et al.  WWOX binds the specific proline-rich ligand PPXY: identification of candidate interacting proteins , 2004, Oncogene.

[10]  Y. Pekarsky,et al.  Functional association between Wwox tumor suppressor protein and p73, a p53 homolog. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[11]  A. Sahin,et al.  Frequent loss of WWOX expression in breast cancer: correlation with estrogen receptor status , 2004, Breast Cancer Research and Treatment.

[12]  J. Ludes-Meyers,et al.  WWOX, the common chromosomal fragile site, FRA16D, cancer gene , 2003, Cytogenetic and Genome Research.

[13]  C. Croce,et al.  FRA3B and other common fragile sites: the weakest links , 2001, Nature Reviews Cancer.

[14]  A. Brenner,et al.  WWOX, the FRA16D gene, behaves as a suppressor of tumor growth. , 2001, Cancer research.

[15]  D J Porteous,et al.  WWOX: A candidate tumor suppressor gene involved in multiple tumor types , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[16]  K. Toyoshima,et al.  Mycobacterium bovis Bacillus Calmette-Guerin and Its Cell Wall Complex Induce a Novel Lysosomal Membrane Protein, SIMPLE, That Bridges the Missing Link between Lipopolysaccharide and p53-inducible Gene, LITAF(PIG7), and Estrogen-inducible Gene, EET-1 * , 2001, The Journal of Biological Chemistry.

[17]  A. Bednarek,et al.  WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3-24.1, a region frequently affected in breast cancer. , 2000, Cancer research.

[18]  E. Schröck,et al.  Frequent dysregulation of the c-maf proto-oncogene at 16q23 by translocation to an Ig locus in multiple myeloma. , 1998, Blood.

[19]  A. Sahin,et al.  Deletion map of chromosome 16q in ductal carcinoma in situ of the breast: refining a putative tumor suppressor gene region. , 1996, Cancer research.

[20]  A. Sahin,et al.  Comparative allelotype of in situ and invasive human breast cancer: high frequency of microsatellite instability in lobular breast carcinomas. , 1995, Cancer research.

[21]  P. Devilee,et al.  At least two different regions are involved in allelic imbalance on chromosome arm 16q in breast cancer , 1994, Genes, chromosomes & cancer.

[22]  N. Nishida,et al.  Accumulation of allelic loss on arms of chromosomes 13q, 16q and 17p in the advanced stages of human hepatocellular carcinoma , 1992, International journal of cancer.

[23]  A. Tanigami,et al.  Allelotype of breast cancer: cumulative allele losses promote tumor progression in primary breast cancer. , 1990, Cancer research.

[24]  W. Isaacs,et al.  Allelic loss of chromosomes 16q and 10q in human prostate cancer. , 1990, Proceedings of the National Academy of Sciences of the United States of America.