Bimodal voltage dependence of TRPA1: mutations of a key pore helix residue reveal strong intrinsic voltage-dependent inactivation
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M. Zhu | Yungang Lu | Jian Xiong | Zhaobing Gao | Yuan-da Zhou | Bingqing Xia | Ping Li | Xueqin Chen | Min Li | Xia Wan
[1] D. Clapham,et al. Analysis of the selectivity filter of the voltage-gated sodium channel NavRh , 2012, Cell Research.
[2] B. Nilius,et al. Bimodal effects of cinnamaldehyde and camphor on mouse TRPA1 , 2013, Pflügers Archiv - European Journal of Physiology.
[3] B. Nilius,et al. The transient receptor potential channel TRPA1: from gene to pathophysiology , 2012, Pflügers Archiv - European Journal of Physiology.
[4] J. Krůšek,et al. Pore Helix Domain Is Critical to Camphor Sensitivity of Transient Receptor Potential Vanilloid 1 Channel , 2012, Anesthesiology.
[5] I. Barvík,et al. C-terminal Acidic Cluster Is Involved in Ca2+-induced Regulation of Human Transient Receptor Potential Ankyrin 1 Channel* , 2012, The Journal of Biological Chemistry.
[6] K. Rowland,et al. Tooth injury increases expression of the cold sensitive TRP channel TRPA1 in trigeminal neurons. , 2011, Archives of oral biology.
[7] B. Nilius,et al. Irritating channels: the case of TRPA1 , 2011, The Journal of physiology.
[8] Eduardo Perozo,et al. Structural mechanism of C-type inactivation in K+ channels , 2010, Nature.
[9] Meng Wu,et al. Isoform-specific Prolongation of Kv7 (KCNQ) Potassium Channel Opening Mediated by New Molecular Determinants for Drug-Channel Interactions* , 2010, The Journal of Biological Chemistry.
[10] Hongzhen Hu,et al. Activation of TRPA1 channels by fenamate nonsteroidal anti-inflammatory drugs , 2010, Pflügers Archiv - European Journal of Physiology.
[11] H. Tan,et al. Cardiac sodium channelopathies , 2009, Pflügers Archiv - European Journal of Physiology.
[12] R. Vennekens,et al. Nicotine activates the chemosensory cation channel TRPA1 , 2009, Nature Neuroscience.
[13] R. Ettrich,et al. Essential role for the putative S6 inner pore region in the activation gating of the human TRPA1 channel. , 2009, Biochimica et biophysica acta.
[14] D. Corey,et al. TRPA1 Modulates Mechanotransduction in Cutaneous Sensory Neurons , 2009, The Journal of Neuroscience.
[15] B. Undem,et al. Nitrooleic Acid, an Endogenous Product of Nitrative Stress, Activates Nociceptive Sensory Nerves via the Direct Activation of TRPA1 , 2009, Molecular Pharmacology.
[16] R. Vennekens,et al. TRPA1 acts as a cold sensor in vitro and in vivo , 2009, Proceedings of the National Academy of Sciences.
[17] Serdar Kuyucak,et al. The Pore Domain Outer Helix Contributes to Both Activation and Inactivation of the hERG K+ Channel* , 2009, Journal of Biological Chemistry.
[18] Donghee Kim,et al. Pore dilation occurs in TRPA1 but not in TRPM8 channels , 2009, Molecular pain.
[19] S. Jordt,et al. Breathtaking TRP channels: TRPA1 and TRPV1 in airway chemosensation and reflex control. , 2008, Physiology.
[20] D. McKemy,et al. The Nociceptor Ion Channel TRPA1 Is Potentiated and Inactivated by Permeating Calcium Ions* , 2008, Journal of Biological Chemistry.
[21] A. Patapoutian,et al. Identification of Transmembrane Domain 5 as a Critical Molecular Determinant of Menthol Sensitivity in Mammalian TRPA1 Channels , 2008, The Journal of Neuroscience.
[22] Donghee Kim,et al. Activation of transient receptor potential A1 channels by mustard oil, tetrahydrocannabinol and Ca2+ reveals different functional channel states , 2008, Neuroscience.
[23] Benjamin R. Myers,et al. A Yeast Genetic Screen Reveals a Critical Role for the Pore Helix Domain in TRP Channel Gating , 2008, Neuron.
[24] P. Hajduk,et al. Molecular Determinants of Species-Specific Activation or Blockade of TRPA1 Channels , 2008, The Journal of Neuroscience.
[25] B. Nilius,et al. Modulation of the transient receptor potential channel TRPA1 by phosphatidylinositol 4,5-biphosphate manipulators , 2008, Pflügers Archiv - European Journal of Physiology.
[26] M. Zhu,et al. Calcium Plays a Central Role in the Sensitization of TRPV3 Channel to Repetitive Stimulations* , 2008, Journal of Biological Chemistry.
[27] D. Andersson,et al. Transient Receptor Potential A1 Is a Sensory Receptor for Multiple Products of Oxidative Stress , 2008, The Journal of Neuroscience.
[28] D. Henze,et al. HC-030031, a TRPA1 selective antagonist, attenuates inflammatory- and neuropathy-induced mechanical hypersensitivity , 2008, Molecular pain.
[29] M. Zhu. Understanding the role of voltage gating of polymodal TRP channels , 2007, The Journal of physiology.
[30] Jing Yao,et al. Uncoupling Proton Activation of Vanilloid Receptor TRPV1 , 2007, The Journal of Neuroscience.
[31] R. Latorre,et al. ThermoTRP channels as modular proteins with allosteric gating. , 2007, Cell calcium.
[32] B. Nilius,et al. Bimodal Action of Menthol on the Transient Receptor Potential Channel TRPA1 , 2007, The Journal of Neuroscience.
[33] A. Basbaum,et al. 4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1 , 2007, Proceedings of the National Academy of Sciences.
[34] G. Gisselmann,et al. Transient Receptor Potential Channel A1 Is Directly Gated by Calcium Ions* , 2007, Journal of Biological Chemistry.
[35] P. Heppenstall,et al. Direct activation of the ion channel TRPA1 by Ca2+ , 2007, Nature Neuroscience.
[36] Peter G. Schultz,et al. Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines , 2007, Nature.
[37] D. Julius,et al. TRP channel activation by reversible covalent modification , 2006, Proceedings of the National Academy of Sciences.
[38] Clifford J. Woolf,et al. TRPA1 Contributes to Cold, Mechanical, and Chemical Nociception but Is Not Essential for Hair-Cell Transduction , 2006, Neuron.
[39] David Julius,et al. TRPA1 Mediates the Inflammatory Actions of Environmental Irritants and Proalgesic Agents , 2006, Cell.
[40] M. Sanguinetti,et al. Differential roles of S6 domain hinges in the gating of KCNQ potassium channels. , 2006, Biophysical journal.
[41] Chou-Long Huang,et al. Conformational changes of pore helix coupled to gating of TRPV5 by protons , 2005, The EMBO journal.
[42] E. Campbell,et al. Voltage Sensor of Kv1.2: Structural Basis of Electromechanical Coupling , 2005, Science.
[43] Bernd Nilius,et al. Gating of TRP channels: a voltage connection? , 2005, The Journal of physiology.
[44] 刘金明,et al. IL-13受体α2降低血吸虫病肉芽肿的炎症反应并延长宿主存活时间[英]/Mentink-Kane MM,Cheever AW,Thompson RW,et al//Proc Natl Acad Sci U S A , 2005 .
[45] K. Nagata,et al. Nociceptor and Hair Cell Transducer Properties of TRPA1, a Channel for Pain and Hearing , 2005, The Journal of Neuroscience.
[46] Benoît Roux,et al. A gate in the selectivity filter of potassium channels. , 2005, Structure.
[47] Michael C Sanguinetti,et al. Regional Specificity of Human ether-a'-go-go-related Gene Channel Activation and Inactivation Gating* , 2005, Journal of Biological Chemistry.
[48] Gea-Ny Tseng,et al. Gating Charges in the Activation and Inactivation Processes of the hERG Channel , 2004, The Journal of general physiology.
[49] Bernd Nilius,et al. The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels , 2004, Nature.
[50] G. Yellen,et al. Intracellular gate opening in Shaker K+ channels defined by high-affinity metal bridges , 2004, Nature.
[51] G. Zamponi,et al. Functional roles of cytoplasmic loops and pore lining transmembrane helices in the voltage‐dependent inactivation of HVA calcium channels , 2004, The Journal of physiology.
[52] D. McKemy,et al. Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1 , 2004, Nature.
[53] Michael C Sanguinetti,et al. Gating currents associated with intramembrane charge displacement in HERG potassium channels , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[54] Peter McIntyre,et al. ANKTM1, a TRP-like Channel Expressed in Nociceptive Neurons, Is Activated by Cold Temperatures , 2003, Cell.
[55] B. Nilius,et al. Mg2+-dependent Gating and Strong Inward Rectification of the Cation Channel TRPV6 , 2003, The Journal of general physiology.
[56] M. Sanguinetti,et al. A mutation in the pore region of HERG K+ channels expressed in Xenopus oocytes reduces rectification by shifting the voltage dependence of inactivation , 1998, The Journal of physiology.
[57] H. Strauss,et al. A quantitative analysis of the activation and inactivation kinetics of HERG expressed in Xenopus oocytes , 1997, The Journal of physiology.
[58] C. Nichols,et al. Inward rectifier potassium channels. , 1997, Annual review of physiology.
[59] Gary Yellen,et al. The inward rectification mechanism of the HERG cardiac potassium channel , 1996, Nature.
[60] A. Fox. Voltage-dependent inactivation of a calcium channel. , 1981, Proceedings of the National Academy of Sciences of the United States of America.
[61] A. Hodgkin,et al. The dual effect of membrane potential on sodium conductance in the giant axon of Loligo , 1952, The Journal of physiology.