SMYD1a protects the heart from ischemic injury by regulating OPA1-mediated cristae remodeling and supercomplex formation
暂无分享,去创建一个
S. Franklin | S. Boudina | K. Funai | Kathryn Davis | Mickey R Miller | J. Durrant | Marta W. Szulik | D. Chaudhuri | Li Wang | Christopher M. Tracy | David R. Eberhardt | Ryan Bia | Samuel M. Hickenlooper | Steven E Valdez | Emilee Horiuchi | Hanin Sheikh | S. Drakos | Sean A. O’very | Maureen A. Walsh | Anil K. Laxman | Linda Sandaklie-Nicolova | Magnus Creed | Cameron Brady | June Garcia-Llana
[1] S. Franklin,et al. Mitochondrial calcium uniporter stabilization preserves energetic homeostasis during Complex I impairment , 2022, Nature Communications.
[2] F. Sachse,et al. EFHD1 ablation inhibits cardiac mitoflash activation and protects cardiomyocytes from ischemia. , 2022, Journal of molecular and cellular cardiology.
[3] S. Franklin,et al. The role of demethylases in cardiac development and disease. , 2021, Journal of molecular and cellular cardiology.
[4] R. Tian,et al. Cardiac Energy Metabolism in Heart Failure , 2021, Circulation research.
[5] Francesca N. Delling,et al. Heart Disease and Stroke Statistics-2021 Update: A Report From the American Heart Association. , 2021, Circulation.
[6] S. Javadov,et al. Mitochondrial respiratory supercomplexes in mammalian cells: structural versus functional role , 2020, Journal of Molecular Medicine.
[7] S. Franklin,et al. Transcriptional regulation by methyltransferases and their role in the heart: highlighting novel emerging functionality. , 2020, American journal of physiology. Heart and circulatory physiology.
[8] Chae-Myeong Ha,et al. Maintaining Myocardial Glucose Utilization in Diabetic Cardiomyopathy Accelerates Mitochondrial Dysfunction , 2020, Diabetes.
[9] A. Kfoury,et al. The Role of Nonglycolytic Glucose Metabolism in Myocardial Recovery Upon Mechanical Unloading and Circulatory Support in Chronic Heart Failure , 2020, Circulation.
[10] J. Plutzky,et al. BET Epigenetic Reader Proteins in Cardiovascular Transcriptional Programs. , 2020, Circulation research.
[11] Chengzhi Lu,et al. Irisin activates Opa1-induced mitophagy to protect cardiomyocytes against apoptosis following myocardial infarction , 2020, Aging.
[12] S. Oka,et al. Multiple Levels of PGC-1α Dysregulation in Heart Failure , 2020, Frontiers in Cardiovascular Medicine.
[13] S. Javadov,et al. OPA1 regulates respiratory supercomplexes assembly: the role of mitochondrial swelling. , 2019, Mitochondrion.
[14] Xinli Hu,et al. NDUFAB1 confers cardio-protection by enhancing mitochondrial bioenergetics through coordination of respiratory complex and supercomplex assembly , 2019, Cell Research.
[15] Shuai Jiang,et al. Mitochondrial electron transport chain, ROS generation and uncoupling (Review) , 2019, International journal of molecular medicine.
[16] Danish Sayed,et al. Recruitment of RNA Polymerase II to Metabolic Gene Promoters Is Inhibited in the Failing Heart Possibly Through PGC-1&agr; (Peroxisome Proliferator-Activated Receptor-&ggr; Coactivator-1&agr;) Dysregulation , 2019, Circulation. Heart failure.
[17] L. Mestroni,et al. Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure , 2018, BMC Genomics.
[18] Wang Wang,et al. Heart specific knockout of Ndufs4 ameliorates ischemia reperfusion injury. , 2018, Journal of molecular and cellular cardiology.
[19] P. Neufer,et al. Targeted overexpression of catalase to mitochondria does not prevent cardioskeletal myopathy in Barth syndrome. , 2018, Journal of molecular and cellular cardiology.
[20] Haley O. Tucker,et al. Histone methyltransferase Smyd1 regulates mitochondrial energetics in the heart , 2018, Proceedings of the National Academy of Sciences.
[21] Anne E Carpenter,et al. CellProfiler 3.0: Next-generation image processing for biology , 2018, PLoS biology.
[22] T. Tuomainen,et al. Heart specific PGC-1&agr; deletion identifies metabolome of cardiac restricted metabolic heart failure , 2018, Cardiovascular research.
[23] S. Franklin,et al. The Smyd Family of Methyltransferases: Role in Cardiac and Skeletal Muscle Physiology and Pathology. , 2018, Current opinion in physiology.
[24] D. Winge,et al. Mitochondrial cardiomyopathies feature increased uptake and diminished efflux of mitochondrial calcium. , 2017, Journal of molecular and cellular cardiology.
[25] Haley O. Tucker,et al. The chromatin-binding protein Smyd1 restricts adult mammalian heart growth. , 2016, American journal of physiology. Heart and circulatory physiology.
[26] P. Neufer,et al. Direct real-time quantification of mitochondrial oxidative phosphorylation efficiency in permeabilized skeletal muscle myofibers. , 2016, American journal of physiology. Cell physiology.
[27] V. Pell,et al. Succinate metabolism: a new therapeutic target for myocardial reperfusion injury. , 2016, Cardiovascular research.
[28] Dean Y. Li,et al. Evidence of Glycolysis Up-Regulation and Pyruvate Mitochondrial Oxidation Mismatch During Mechanical Unloading of the Failing Human Heart , 2016, JACC. Basic to translational science.
[29] J. Auwerx,et al. Analysis of Mitochondrial Respiratory Chain Supercomplexes Using Blue Native Polyacrylamide Gel Electrophoresis (BN‐PAGE) , 2016, Current protocols in mouse biology.
[30] L. Scorrano,et al. Mitochondrial Cristae: Where Beauty Meets Functionality. , 2016, Trends in biochemical sciences.
[31] Haley O. Tucker,et al. Defective myogenesis in the absence of the muscle-specific lysine methyltransferase SMYD1. , 2016, Developmental biology.
[32] P. Bénit,et al. Imbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in mice , 2015, Science.
[33] N. Mewton,et al. Cyclosporine before PCI in Patients with Acute Myocardial Infarction. , 2015, The New England journal of medicine.
[34] L. Scorrano,et al. The Opa1-Dependent Mitochondrial Cristae Remodeling Pathway Controls Atrophic, Apoptotic, and Ischemic Tissue Damage , 2015, Cell metabolism.
[35] N. Uriel,et al. Spotlight on new therapies in heart failure. , 2015, Current opinion in cardiology.
[36] S. Franklin,et al. Metabolic Remodeling in Moderate Synchronous versus Dyssynchronous Pacing-Induced Heart Failure: Integrated Metabolomics and Proteomics Study , 2015, PloS one.
[37] David S. Park,et al. OPA1‐dependent cristae modulation is essential for cellular adaptation to metabolic demand , 2014, The EMBO journal.
[38] R. Tian,et al. Promoting PGC-1α-driven mitochondrial biogenesis is detrimental in pressure-overloaded mouse hearts. , 2014, American journal of physiology. Heart and circulatory physiology.
[39] Frank B Sachse,et al. Myocardial atrophy and chronic mechanical unloading of the failing human heart: implications for cardiac assist device-induced myocardial recovery. , 2014, Journal of the American College of Cardiology.
[40] W. Ward,et al. Maintaining PGC‐1α expression following pressure overload‐induced cardiac hypertrophy preserves angiogenesis but not contractile or mitochondrial function , 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[41] Gary D Bader,et al. A draft map of the human proteome , 2014, Nature.
[42] E. Rugarli,et al. The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission , 2014, The Journal of cell biology.
[43] G. Ewald,et al. Deep RNA Sequencing Reveals Dynamic Regulation of Myocardial Noncoding RNAs in Failing Human Heart and Remodeling With Mechanical Circulatory Support , 2014, Circulation.
[44] Sara Cipolat,et al. Mitochondrial Cristae Shape Determines Respiratory Chain Supercomplexes Assembly and Respiratory Efficiency , 2013, Cell.
[45] C. López-Otín,et al. Supercomplex Assembly Determines Electron Flux in the Mitochondrial Electron Transport Chain , 2013, Science.
[46] D. Meyerholz,et al. Principles for Valid Histopathologic Scoring in Research , 2013, Veterinary pathology.
[47] D. Kass,et al. Animal models of heart failure: a scientific statement from the American Heart Association. , 2012, Circulation research.
[48] S. Franklin,et al. Quantitative Analysis of the Chromatin Proteome in Disease Reveals Remodeling Principles and Identifies High Mobility Group Protein B2 as a Regulator of Hypertrophic Growth* , 2012, Molecular & Cellular Proteomics.
[49] P. Ping,et al. Specialized compartments of cardiac nuclei exhibit distinct proteomic anatomy* , 2011, Molecular & Cellular Proteomics.
[50] Jun Ye,et al. Crystal Structure of Cardiac-specific Histone Methyltransferase SmyD1 Reveals Unusual Active Site Architecture* , 2010, The Journal of Biological Chemistry.
[51] G. Lopaschuk,et al. Energy Metabolic Phenotype of the Cardiomyocyte During Development, Differentiation, and Postnatal Maturation , 2010, Journal of cardiovascular pharmacology.
[52] Qizhi Gong,et al. Mitochondrial OPA1, apoptosis, and heart failure. , 2009, Cardiovascular research.
[53] S. Boudina,et al. Contribution of Impaired Myocardial Insulin Signaling to Mitochondrial Dysfunction and Oxidative Stress in the Heart , 2009, Circulation.
[54] J. Manson,et al. Vitamins E and C in the prevention of cardiovascular disease in men: the Physicians' Health Study II randomized controlled trial. , 2008, JAMA.
[55] Randall J. Lee,et al. Myocardial infarct size measurement in the mouse chronic infarction model: comparison of area- and length-based approaches. , 2007, Journal of applied physiology.
[56] P. Razeghi,et al. Return to the fetal gene program protects the stressed heart: a strong hypothesis , 2007, Heart Failure Reviews.
[57] Sara Cipolat,et al. OPA1 Controls Apoptotic Cristae Remodeling Independently from Mitochondrial Fusion , 2006, Cell.
[58] B. Spiegelman,et al. Transverse aortic constriction leads to accelerated heart failure in mice lacking PPAR-γ coactivator 1α , 2006 .
[59] Xungang Tan,et al. SmyD1, a histone methyltransferase, is required for myofibril organization and muscle contraction in zebrafish embryos , 2006 .
[60] J. Saffitz,et al. Cardiac-Specific Induction of the Transcriptional Coactivator Peroxisome Proliferator-Activated Receptor &ggr; Coactivator-1&agr; Promotes Mitochondrial Biogenesis and Reversible Cardiomyopathy in a Developmental Stage-Dependent Manner , 2004, Circulation research.
[61] T. Thum,et al. Hallmarks of ion channel gene expression in end‐stage heart failure , 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[62] D. Srivastava,et al. Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis , 2002, Nature Genetics.
[63] H. Suryapranata,et al. The Na(+)/H(+) exchange inhibitor eniporide as an adjunct to early reperfusion therapy for acute myocardial infarction. Results of the evaluation of the safety and cardioprotective effects of eniporide in acute myocardial infarction (ESCAMI) trial. , 2001, Journal of the American College of Cardiology.
[64] J. Saffitz,et al. Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis. , 2000, The Journal of clinical investigation.
[65] I. Piña,et al. Evaluating quality of care for patients with heart failure. , 2000, Circulation.
[66] G. Lopaschuk,et al. Developmental changes in energy substrate use by the heart. , 1992, Cardiovascular research.
[67] Kai Huang,et al. Assessing Mitochondrial Bioenergetics in Isolated Mitochondria from Mouse Heart Tissues Using Oroboros 2k-Oxygraph. , 2019, Methods in molecular biology.
[68] B. Spiegelman,et al. Transverse aortic constriction leads to accelerated heart failure in mice lacking PPAR-gamma coactivator 1alpha. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[69] M. L. Kaplan,et al. Alterations in gene expression in the rat heart after chronic pathological and physiological loads. , 1994, Journal of molecular and cellular cardiology.