The γ2 subunit of GABAA receptors is required for maintenance of receptors at mature synapses

[1]  J. Fritschy,et al.  Formation and plasticity of GABAergic synapses: physiological mechanisms and pathophysiological implications. , 2003, Pharmacology & therapeutics.

[2]  M. Matsuda,et al.  Molecules interacting with PRIP-2, a novel Ins(1,4,5)P3 binding protein type 2: Comparison with PRIP-1. , 2002, Life sciences.

[3]  Y. Ben-Ari,et al.  Paracrine Intercellular Communication by a Ca2+- and SNARE-Independent Release of GABA and Glutamate Prior to Synapse Formation , 2002, Neuron.

[4]  I. Brünig,et al.  GABAergic and glutamatergic terminals differentially influence the organization of GABAergic synapses in rat cerebellar granule cells in vitro , 2002, Neuroscience.

[5]  Christian Rosenmund,et al.  Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[6]  I. Knuesel,et al.  GABAergic Terminals Are Required for Postsynaptic Clustering of Dystrophin But Not of GABAA Receptors and Gephyrin , 2002, The Journal of Neuroscience.

[7]  D. Choquet,et al.  Regulation of AMPA receptor lateral movements , 2002, Nature.

[8]  A. D. De Blas,et al.  GABAergic Innervation Organizes Synaptic and Extrasynaptic GABAA Receptor Clustering in Cultured Hippocampal Neurons , 2002, The Journal of Neuroscience.

[9]  Steven Petrou,et al.  Truncation of the GABA(A)-receptor gamma2 subunit in a family with generalized epilepsy with febrile seizures plus. , 2002, American journal of human genetics.

[10]  R. Dolmetsch,et al.  Signaling to the Nucleus by an L-type Calcium Channel-Calmodulin Complex Through the MAP Kinase Pathway , 2001, Science.

[11]  Istvan Mody,et al.  Distinguishing Between GABAA Receptors Responsible for Tonic and Phasic Conductances , 2001, Neurochemical Research.

[12]  R. Olsen,et al.  The Subcellular Distribution of GABARAP and Its Ability to Interact with NSF Suggest a Role for This Protein in the Intracellular Transport of GABAA Receptors , 2001, Molecular and Cellular Neuroscience.

[13]  M. Poo,et al.  GABA Itself Promotes the Developmental Switch of Neuronal GABAergic Responses from Excitation to Inhibition , 2001, Cell.

[14]  K. Ballanyi,et al.  Disruption of KCC2 Reveals an Essential Role of K-Cl Cotransport Already in Early Synaptic Inhibition , 2001, Neuron.

[15]  Michel Baulac,et al.  First genetic evidence of GABAA receptor dysfunction in epilepsy: a mutation in the γ2-subunit gene , 2001, Nature Genetics.

[16]  A. Triller,et al.  Fast and reversible trapping of surface glycine receptors by gephyrin , 2001, Nature Neuroscience.

[17]  A. Craig,et al.  Mismatched Appositions of Presynaptic and Postsynaptic Components in Isolated Hippocampal Neurons , 2000, The Journal of Neuroscience.

[18]  S. Moss,et al.  Constitutive Endocytosis of GABAA Receptors by an Association with the Adaptin AP2 Complex Modulates Inhibitory Synaptic Currents in Hippocampal Neurons , 2000, The Journal of Neuroscience.

[19]  J. Benson,et al.  Single‐channel properties of neuronal GABAA receptors from mice lacking the γ2 subunit , 2000, The Journal of physiology.

[20]  H. Wässle,et al.  The gamma-aminobutyric acid type A receptor (GABAAR)-associated protein GABARAP interacts with gephyrin but is not involved in receptor anchoring at the synapse. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[21]  M. Sassoè-Pognetto,et al.  Gephyrin, a major postsynaptic protein of GABAergic synapses , 2000, The European journal of neuroscience.

[22]  R. Harris,et al.  Rescue of γ2 subunit‐deficient mice by transgenic overexpression of the GABAA receptor γ2S or γ2L subunit isoforms , 2000 .

[23]  T. Südhof,et al.  Synaptic assembly of the brain in the absence of neurotransmitter secretion. , 2000, Science.

[24]  N. Brandon,et al.  Cell surface stability of gamma-aminobutyric acid type A receptors. Dependence on protein kinase C activity and subunit composition. , 1999, The Journal of biological chemistry.

[25]  J. Brandstätter,et al.  Loss of Postsynaptic GABAA Receptor Clustering in Gephyrin-Deficient Mice , 1999, The Journal of Neuroscience.

[26]  J. Benson,et al.  Postsynaptic clustering of γ-aminobutyric acid type A receptors by the γ3 subunit in vivo , 1999 .

[27]  Bernhard Lüscher,et al.  Decreased GABAA-receptor clustering results in enhanced anxiety and a bias for threat cues , 1999, Nature Neuroscience.

[28]  C. Lobe,et al.  Z/AP, a double reporter for cre-mediated recombination. , 1999, Developmental biology.

[29]  C. Bergounioux,et al.  Presence of the vesicular inhibitory amino acid transporter in GABAergic and glycinergic synaptic terminal boutons , 1998 .

[30]  N. Brandon,et al.  GABAA-receptor-associated protein links GABAA receptors and the cytoskeleton , 1999, Nature.

[31]  Bernhard Lüscher,et al.  Postsynaptic clustering of major GABAA receptor subtypes requires the γ2 subunit and gephyrin , 1998, Nature Neuroscience.

[32]  J. Kirsch,et al.  Glycine-receptor activation is required for receptor clustering in spinal neurons , 1998, Nature.

[33]  A. Triller,et al.  Strychnine-sensitive stabilization of postsynaptic glycine receptor clusters. , 1998, Journal of cell science.

[34]  A. Wenzel,et al.  Synapse‐specific localization of NMDA and GABAA receptor subunits revealed by antigen‐retrieval immunohistochemistry , 1998, The Journal of comparative neurology.

[35]  E. Sigel,et al.  Proteins Associated with α1‐Subunit‐Containing GABAA Receptors from Bovine Brain , 1997 .

[36]  P. Somogyi,et al.  The γ2 Subunit of the GABAA Receptor is Concentrated in Synaptic Junctions Containing the α1 and β 2 3 Subunits in Hippocampus, Cerebellum and Globus Pallidus , 1996, Neuropharmacology.

[37]  David J. Anderson,et al.  Subregion- and Cell Type–Restricted Gene Knockout in Mouse Brain , 1996, Cell.

[38]  E. Kandel,et al.  The 3'-untranslated region of CaMKII alpha is a cis-acting signal for the localization and translation of mRNA in dendrites. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[39]  S. Dymecki.  Flp recombinase promotes site-specific DNA recombination in embryonic stem cells and transgenic mice. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[40]  Dieter Langosch,et al.  Identification of a gephyrin binding motif on the glycine receptor β subunit , 1995, Neuron.

[41]  J. Fritschy,et al.  GABAA‐receptor heterogeneity in the adult rat brain: Differential regional and cellular distribution of seven major subunits , 1995, The Journal of comparative neurology.

[42]  J. Henley,et al.  Receptor and Ion channel Trafficking , 2002 .

[43]  David A. Williams,et al.  Mutant GABAA receptor γ2-subunit in childhood absence epilepsy and febrile seizures , 2001, Nature Genetics.

[44]  K. Baer.  Postsynaptic clustering of GABAA receptors by the γ3 subunit in vivo , 1999 .