Autogeneous elbow fistulas: the effect of diabetes mellitus on maturation, patency, and complication rates.

OBJECTIVES diabetes mellitus is an increasingly common cause of end stage renal failure (ESRF) and the establishment of adequate permanent vascular access for dialysis is a major cause of morbidity and mortality in these patients. The aim of this study was to compare the availability of suitable vein, maturation rates, patency and complication rates of autogeneous elbow fistulas in diabetics and non-diabetics at a single centre where an autogeneous vein only policy is employed. DESIGN retrospective series. PATIENTS AND METHODS two hundred and ninety-three elbow fistulas were attempted in 232 patients over a seven year period, [median age 60 years (range 14-94 years)], of which 210 were in non-diabetic and 83 were in diabetic patients. The diabetic group had a significantly higher proportion of male patients (p < 0.05), peripheral vascular disease and established ESRF. RESULTS there was a trend towards a higher technical success rate in the non-diabetic group (98% versus 93% p = 0.057). There was no significant difference between the primary failure rate, fistula maturation rate, revision rate or incidence of complications between the two groups. Diabetes had no effect on cumulative secondary fistula patency even when stratified for Type 1/Type 2 diabetes, female sex, old age or primary versus subsequent procedures. CONCLUSION diabetes mellitus has no significant detrimental effect on outcome following formation of autogeneous elbow fistulas for haemodialysis.

[1]  C. Stehman-Breen,et al.  Determinants of type and timing of initial permanent hemodialysis vascular access. , 2000, Kidney international.

[2]  P. Kalman,et al.  A practical approach to vascular access for hemodialysis and predictors of success. , 1999, Journal of vascular surgery.

[3]  M. Clèries,et al.  Vascular access for haemodialysis--an epidemiological study of the Catalan Renal Registry. , 1999, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[4]  D. Fliser,et al.  How can we improve prognosis in diabetic patients with end-stage renal disease? , 1999, Diabetes Care.

[5]  F. Torella,et al.  Arteriovenous fistula using transposed basilic vein. , 1998, The British journal of surgery.

[6]  J. Himmelfarb,et al.  Hemodialysis access failure: a call to action. , 1998, Kidney international.

[7]  C. Yen,et al.  Effects of Age and Diabetes on Blood Flow Rate and Primary Outcome of Newly Created Hemodialysis Arteriovenous Fistulas , 1998, American Journal of Nephrology.

[8]  M. Lachat,et al.  Long-term function of vascular access for hemodialysis. , 1996, Clinical transplantation.

[9]  D. Taube,et al.  Elbow arteriovenous fistulas for chronic haemodialysis , 1994, The British journal of surgery.

[10]  J. Berlin,et al.  Hemodialysis vascular access morbidity in the United States. , 1993, Kidney international.

[11]  D. Windus Permanent vascular access: a nephrologist's view. , 1993, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[12]  J. Delmez,et al.  Prosthetic fistula survival and complications in hemodialysis patients: effects of diabetes and age. , 1992, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[13]  L. R. King,et al.  Comparison of autogenous fistula versus expanded polytetrafluoroethylene graft fistula for angioaccess in hemodialysis. , 1986, American journal of surgery.

[14]  P. Bell,et al.  Prospective study of dialysis fistulas: Problem patients and their treatment , 1982, The British journal of surgery.

[15]  A. Hingorani,et al.  Changes in the practice of angioaccess surgery: impact of dialysis outcome and quality initiative recommendations. , 2000, Journal of vascular surgery.

[16]  A. Hakaim,et al.  Superior maturation and patency of primary brachiocephalic and transposed basilic vein arteriovenous fistulae in patients with diabetes. , 1998, Journal of vascular surgery.

[17]  J. Chazan,et al.  Long-term survival of vascular accesses in a large chronic hemodialysis population. , 1995, Nephron.