A Genome-wide CRISPR Screen Identifies ZCCHC14 as a Host Factor Required for Hepatitis B Surface Antigen Production.
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Meghan M. Holdorf | P. Feucht | D. Ganem | G. Hoffman | Alicia Lindeman | Carsten Russ | Tiffany Tsang | Scott Clarkson | K. Uehara | Frederic D. Sigoillot | Lili Xie | Darlene Chen | Anastasia Hyrina | Christopher Jones | Nadire R. Cochran
[1] J. Young,et al. PAPD5/7 Are Host Factors That Are Required for Hepatitis B Virus RNA Stabilization , 2019, Hepatology.
[2] Xingchun Han,et al. Discovery of RG7834: The First-in-Class Selective and Orally Available Small Molecule Hepatitis B Virus Expression Inhibitor with Novel Mechanism of Action. , 2018, Journal of medicinal chemistry.
[3] V. Kim,et al. Mixed tailing by TENT4A and TENT4B shields mRNA from rapid deadenylation , 2018, Science.
[4] George-Lucian Moldovan,et al. PARP10 promotes cellular proliferation and tumorigenesis by alleviating replication stress , 2018, bioRxiv.
[5] F. Nigsch,et al. Genome-wide CRISPR screen for PARKIN regulators reveals transcriptional repression as a determinant of mitophagy , 2017, Proceedings of the National Academy of Sciences.
[6] Wenzhe Lu,et al. A novel orally available small molecule that inhibits hepatitis B virus expression. , 2017, Journal of hepatology.
[7] F. Zoulim,et al. Intrahepatic innate immune response pathways are downregulated in untreated chronic hepatitis B. , 2017, Journal of hepatology.
[8] D. Durantel,et al. Interplay between the Hepatitis B Virus and Innate Immunity: From an Understanding to the Development of Therapeutic Concepts , 2017, Viruses.
[9] J. Carette,et al. A CRISPR toolbox to study virus–host interactions , 2017, Nature Reviews Microbiology.
[10] Gregory McAllister,et al. Identification of a novel NAMPT inhibitor by CRISPR/Cas9 chemogenomic profiling in mammalian cells , 2017, Scientific Reports.
[11] Craig M. Crews,et al. Induced protein degradation: an emerging drug discovery paradigm , 2016, Nature Reviews Drug Discovery.
[12] T. Pihlajaniemi,et al. Small-Molecule Chemical Probe Rescues Cells from Mono-ADP-Ribosyltransferase ARTD10/PARP10-Induced Apoptosis and Sensitizes Cancer Cells to DNA Damage. , 2016, Cell chemical biology.
[13] John A. Tallarico,et al. Functional CRISPR screening identifies the ufmylation pathway as a regulator of SQSTM1/p62 , 2016, eLife.
[14] C. Kuny,et al. Virus–Host Interactions and the ARTD/PARP Family of Enzymes , 2016, PLoS pathogens.
[15] Meghan M. Holdorf,et al. Mapping of histone modifications in episomal HBV cccDNA uncovers an unusual chromatin organization amenable to epigenetic manipulation , 2015, Proceedings of the National Academy of Sciences.
[16] O. Hofmann,et al. VarDict: a novel and versatile variant caller for next-generation sequencing in cancer research , 2016, Nucleic acids research.
[17] M. Nassal. HBV cccDNA: viral persistence reservoir and key obstacle for a cure of chronic hepatitis B , 2015, Gut.
[18] F. Zoulim,et al. Antiviral therapies and prospects for a cure of chronic hepatitis B. , 2015, Cold Spring Harbor perspectives in medicine.
[19] H. Chan,et al. Hepatitis B virus infection , 2014, The Lancet.
[20] W. Huber,et al. Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2 , 2014, Genome Biology.
[21] Piero Carninci,et al. PAPD5-mediated 3′ adenylation and subsequent degradation of miR-21 is disrupted in proliferative disease , 2014, Proceedings of the National Academy of Sciences.
[22] C. Semenkovich,et al. Peroxisomes: a nexus for lipid metabolism and cellular signaling. , 2014, Cell metabolism.
[23] A. Bertoletti,et al. Innate and adaptive immune responses in chronic hepatitis B virus infections: towards restoration of immune control of viral infection , 2011, Gut.
[24] Megha K. Purohit,et al. Air1 Zinc Knuckles 4 and 5 and a Conserved IWRXY Motif Are Critical for the Function and Integrity of the Trf4/5-Air1/2-Mtr4 Polyadenylation (TRAMP) RNA Quality Control Complex* , 2011, The Journal of Biological Chemistry.
[25] K. Borroto-Esoda,et al. HBV DNA replication mediated by cloned patient HBV reverse transcriptase genes from HBV genotypes A-H and its use in antiviral phenotyping assays. , 2011, Journal of virological methods.
[26] S. Hamill,et al. Structure and function of the polymerase core of TRAMP, a RNA surveillance complex , 2010, Proceedings of the National Academy of Sciences.
[27] R. Brodsky. How I treat paroxysmal nocturnal hemoglobinuria. , 2009, Blood.
[28] Cole Trapnell,et al. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome , 2009, Genome Biology.
[29] D. Tollervey,et al. The Many Pathways of RNA Degradation , 2009, Cell.
[30] J. Hagman,et al. The 'zinc knuckle' motif of Early B cell Factor is required for transcriptional activation of B cell-specific genes. , 2008, Molecular immunology.
[31] S. Häfner,et al. Solution structure of stem-loop α of the hepatitis B virus post-transcriptional regulatory element , 2008, Nucleic acids research.
[32] R. König,et al. A probability-based approach for the analysis of large-scale RNAi screens , 2007, Nature Methods.
[33] Keith Bowman,et al. Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs , 2005, Nature Biotechnology.
[34] E. Petfalski,et al. RNA Degradation by the Exosome Is Promoted by a Nuclear Polyadenylation Complex , 2005, Cell.
[35] W. Keller,et al. A New Yeast Poly(A) Polymerase Complex Involved in RNA Quality Control , 2005, PLoS biology.
[36] S. Goff,et al. Inhibition of Retroviral RNA Production by ZAP, a CCCH-Type Zinc Finger Protein , 2002, Science.
[37] Alexander Bürkle,et al. Increase in de novo HBV DNA integrations in response to oxidative DNA damage or inhibition of poly(ADP‐ribosyl)ation , 2002, Hepatology.
[38] H. Tang,et al. Transcriptional regulation of hepatitis B virus by nuclear hormone receptors is a critical determinant of viral tropism. , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[39] J. Peters,et al. In Vivo Regulation of Hepatitis B Virus Replication by Peroxisome Proliferators , 1999, Journal of Virology.
[40] T. Yen,et al. Hepatitis B virus RNA element that facilitates accumulation of surface gene transcripts in the cytoplasm , 1994, Journal of virology.
[41] T. Liang,et al. A novel hepatitis B virus (HBV) genetic element with Rev response element-like properties that is essential for expression of HBV gene products , 1993, Molecular and cellular biology.
[42] S. Fuller,et al. Hepatitis B surface antigen assembles in a post-ER, pre-Golgi compartment , 1992, The Journal of cell biology.
[43] M. Umeda,et al. Lipid composition of hepatitis B virus surface antigen particles and the particle-producing human hepatoma cell lines. , 1990, Journal of lipid research.
[44] D. Ganem,et al. Sequences 5' to the polyadenylation signal mediate differential poly(A) site use in hepatitis B viruses. , 1990, Genes & development.
[45] V. Lingappa,et al. Secreted hepatitis B surface antigen polypeptides are derived from a transmembrane precursor , 1988, The Journal of cell biology.
[46] A. Levinson,et al. Analysis of processing and polyadenylation signals of the hepatitis B virus surface antigen gene by using simian virus 40-hepatitis B virus chimeric plasmids , 1983, Molecular and cellular biology.
[47] A. Lee,et al. HBsAg mRNA degradation induced by a dihydroquinolizinone compound depends on the HBV posttranscriptional regulatory element , 2018, Antiviral research.
[48] Jeremy L Jenkins,et al. Identifying compound efficacy targets in phenotypic drug discovery. , 2016, Drug discovery today.