Common and specific gait patterns in people with varying anatomical levels of lower limb amputation and different prosthetic components.

The present study's aim was to identify the kinematic and kinetic gait patterns and to measure the energy consumption in people with amputation according to both the anatomical level of amputation and the type of prosthetic components in comparison with a control group matched for the gait speed. Fifteen subjects with unilateral transtibial amputation (TTA), forty with unilateral transfemoral amputation (TFA) (9 with mechanical, 17 with CLeg and 14 with Genium prosthesis) and forty healthy subjects were recruited. We computed the time-distance gait parameters; the range of angular motion (RoM) at hip, knee and ankle joints, and at the trunk and pelvis; the values of the 2 peaks of vertical force curve; the full width at half maximum (FWHM) and center of activity (CoA) of vertical force; the mechanical behavior in terms of energy recovery (R-step) and energy consumption. The main results were: i) both TTA and TFA show a common gait pattern characterized by a symmetric increase of step length, step width, double support duration, pelvic obliquity, trunk lateral bending and trunk rotation RoMs compared to control groups. They show also an asymmetric increase of stance duration and of Peak1 in non-amputated side and a decrease of ankle RoM in amputated side; ii) only TFA show a specific gait pattern, depending on the level of amputation, characterized by a symmetric reduction of R-step and an asymmetric decrease of stance duration, CoA and FWHM and an increase of Peak1 in the amputated side and of hip and knee RoM, CoA and FWHM in the non-amputated side; iii) people with amputation with Genium prosthesis show a longer step length and increased hip and knee RoMs compared to people with amputation with mechanical prosthesis who conversely show an increased pelvic obliquity: these are specific gait patterns depending of the type of prosthesis. In conclusion, we identified both common and specific gait patterns in people with amputation, either regardless of, or according to their level of amputation and the type of prosthetic component.

[1]  Sandra J. Olney,et al.  Kinematic and Kinetic Variations of Below-Knee Amputee Gait , 2002 .

[2]  Hartmut Witte,et al.  ISB recommendation on definitions of joint coordinate system of various joints for the reporting of human joint motion--part I: ankle, hip, and spine. International Society of Biomechanics. , 2002, Journal of biomechanics.

[3]  Marco Iosa,et al.  Assessment of gait stability, harmony, and symmetry in subjects with lower-limb amputation evaluated by trunk accelerations. , 2014, Journal of rehabilitation research and development.

[4]  D. Gates,et al.  Assessing preparative gait adaptations in persons with transtibial amputation in response to repeated medial-lateral perturbations. , 2014, Gait & posture.

[5]  T. Lejeune,et al.  Effect of speed on kinematic, kinetic, electromyographic and energetic reference values during treadmill walking , 2008, Neurophysiologie Clinique/Clinical Neurophysiology.

[6]  Bryan Buchholz,et al.  ISB recommendation on definitions of joint coordinate systems of various joints for the reporting of human joint motion--Part II: shoulder, elbow, wrist and hand. , 2005, Journal of biomechanics.

[7]  M Rinaldi,et al.  Global lower limb muscle coactivation during walking at different speeds: Relationship between spatio-temporal, kinematic, kinetic, and energetic parameters. , 2018, Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology.

[8]  Silvia Conforto,et al.  Modular motor control of the sound limb in gait of people with trans-femoral amputation , 2019, Journal of NeuroEngineering and Rehabilitation.

[9]  J. Sanders,et al.  Effects of alignment changes on stance phase pressures and shear stresses on transtibial amputees: measurements from 13 transducer sites. , 1998, IEEE transactions on rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society.

[10]  Martin Seyr,et al.  Activities of Daily Living: Genium Bionic Prosthetic Knee Compared with C-Leg , 2013 .

[11]  C. Detrembleur,et al.  Energy cost, mechanical work, and efficiency of hemiparetic walking. , 2003, Gait & posture.

[12]  Courtney E. Shell,et al.  The effects of prosthetic foot stiffness on transtibial amputee walking mechanics and balance control during turning , 2017, Clinical biomechanics.

[13]  M Jason Highsmith,et al.  Functional performance differences between the Genium and C-Leg prosthetic knees and intact knees. , 2016, Journal of rehabilitation research and development.

[14]  P. Leva Adjustments to Zatsiorsky-Seluyanov's segment inertia parameters. , 1996 .

[15]  G. Cavagna,et al.  Pendular energy transduction within the step in human walking. , 2002, The Journal of experimental biology.

[16]  S. Wolf,et al.  Biomechanical analysis of ramp ambulation of transtibial amputees with an adaptive ankle foot system. , 2010, Gait & posture.

[17]  R. B. Davis,et al.  A gait analysis data collection and reduction technique , 1991 .

[18]  Francesco Lacquaniti,et al.  Gait Patterns in Patients with Hereditary Spastic Paraparesis , 2016, PloS one.

[19]  J. Perry,et al.  A personalised exercise programme for individuals with lower limb amputation reduces falls and improves gait biomechanics: A block randomised controlled trial. , 2018, Gait & posture.

[20]  Alberto Esquenazi,et al.  Gait analysis in lower-limb amputation and prosthetic rehabilitation. , 2014, Physical medicine and rehabilitation clinics of North America.

[21]  A. Hof,et al.  Gait initiation in lower limb amputees. , 2008, Gait & posture.

[22]  Jacqueline S. Hebert,et al.  Maintaining stable transfemoral amputee gait on level, sloped and simulated uneven conditions in a virtual environment , 2019, Disability and rehabilitation. Assistive technology.

[23]  A. Lees,et al.  Adjustments in gait symmetry with walking speed in trans-femoral and trans-tibial amputees. , 2003, Gait & posture.

[24]  M Jason Highsmith,et al.  Kinetic asymmetry in transfemoral amputees while performing sit to stand and stand to sit movements. , 2011, Gait & posture.

[25]  Mariano Serrao,et al.  Foot drop and plantar flexion failure determine different gait strategies in Charcot-Marie-Tooth patients. , 2007, Clinical biomechanics.

[26]  Laura Rocchi,et al.  Recommended number of strides for automatic assessment of gait symmetry and regularity in above-knee amputees by means of accelerometry and autocorrelation analysis , 2012, Journal of NeuroEngineering and Rehabilitation.

[27]  Edward D Lemaire,et al.  Understanding dynamic stability from pelvis accelerometer data and the relationship to balance and mobility in transtibial amputees. , 2015, Gait & posture.

[28]  Silvia Conforto,et al.  Global Muscle Coactivation of the Sound Limb in Gait of People with Transfemoral and Transtibial Amputation , 2020, Sensors.

[29]  Jason A. Schoen,et al.  Comparison of transtibial amputee and non-amputee biomechanics during a common turning task. , 2011, Gait & posture.

[30]  G. Cavagna,et al.  The sources of external work in level walking and running. , 1976, The Journal of physiology.

[31]  Warren S. Grundfest,et al.  A Prototype Haptic Feedback System for Lower-Limb Prostheses and Sensory Neuropathy , 2008, MMVR.

[32]  P. Blume,et al.  Prosthetic options available for the diabetic lower limb amputee. , 2014, Clinics in podiatric medicine and surgery.

[33]  H. Skinner,et al.  Gait initiation of persons with below-knee amputation: the characterization and comparison of force profiles. , 1995, Journal of rehabilitation research and development.

[34]  Richard R Neptune,et al.  Compensatory mechanisms of transtibial amputees during circular turning. , 2011, Gait & posture.

[35]  F. Lacquaniti,et al.  Locomotor body scheme. , 2011, Human movement science.

[36]  Felix Kluge,et al.  Speed dependent effects of laterally wedged insoles on gait biomechanics in healthy subjects. , 2017, Gait & posture.

[37]  Gary L. Smidt,et al.  Gait in Rehabilitation , 1990 .

[38]  S. Conforto,et al.  Mechanical lifting energy consumption in work activities designed by means of the “revised NIOSH lifting equation” , 2017, Industrial health.

[39]  G. Holmes,et al.  Sensory disturbances from cerebral lesions , 1911 .

[40]  Cristina Masella,et al.  Stratified cost-utility analysis of C-Leg versus mechanical knees: Findings from an Italian sample of transfemoral amputees , 2017, Prosthetics and orthotics international.