Forward-viewing resonant fiber-optic scanning endoscope of appropriate scanning speed for 3D OCT imaging

A forward-viewing resonant fiber-optic endoscope of a scanning speed appropriate for a high-speed Fourier-domain optical coherence tomography (FD-OCT) system was developed to enable real-time, three-dimensional endoscopic OCT imaging. A new method was explored to conveniently tune the scanning frequency of a resonant fiber-optic scanner, by properly selecting the fiber-optic cantilever length, partially changing the mechanical property of the cantilever, and adding a weight to the cantilever tip. Systematic analyses indicated the resonant scanning frequency can be tuned over two orders of magnitude spanning from ~10Hz to ~kHz. Such a flexible scanning frequency range makes it possible to set an appropriate scanning speed of the endoscope to match the different A-scan rates of a variety of FD-OCT systems. A 2.4-mm diameter, 62.5-Hz scanning endoscope appropriate to work with a 40-kHz swept-source OCT (SS-OCT) system was developed and demonstrated for 3D OCT imaging of biological tissues.

[1]  J. Fujimoto,et al.  Imaging needle for optical coherence tomography. , 2000, Optics letters.

[2]  Thomas de Quincey.  [C] , 2000, The Works of Thomas De Quincey, Vol. 1: Writings, 1799–1820.

[3]  Xingde Li,et al.  Rapid-scanning forward-imaging miniature endoscope for real-time optical coherence tomography. , 2004, Optics letters.

[4]  Changhuei Yang,et al.  Sensitivity advantage of swept source and Fourier domain optical coherence tomography. , 2003, Optics express.

[5]  J. Fujimoto,et al.  Ultrahigh speed spectral / Fourier domain OCT ophthalmic imaging at 70,000 to 312,500 axial scans per second. , 2008, Optics express.

[6]  B. Bouma,et al.  Improved signal-to-noise ratio in spectral-domain compared with time-domain optical coherence tomography. , 2003, Optics letters.

[7]  A. Fercher,et al.  Measurement of intraocular distances by backscattering spectral interferometry , 1995 .

[8]  J. Fujimoto,et al.  Buffered Fourier domain mode locking: Unidirectional swept laser sources for optical coherence tomography imaging at 370,000 lines/s. , 2006, Optics letters.

[9]  Bart Johnson,et al.  Compact ultrafast reflective Fabry-Perot tunable lasers for OCT imaging applications , 2010, BiOS.

[10]  Guann-Pyng Li,et al.  Low-voltage polymer-based scanning cantilever for in vivo optical coherence tomography. , 2005, Optics letters.

[11]  J. Fujimoto,et al.  Optical coherence tomography using a frequency-tunable optical source. , 1997, Optics letters.

[12]  Xingde Li,et al.  High-resolution OCT balloon imaging catheter with astigmatism correction. , 2009, Optics letters.

[13]  Zahid Yaqoob,et al.  Paired-angle-rotation scanning optical coherence tomography forward-imaging probe. , 2006, Optics letters.

[14]  S Yazdanfar,et al.  Electrostatic micromachine scanning mirror for optical coherence tomography. , 2003, Optics letters.

[15]  A. Fercher,et al.  Performance of fourier domain vs. time domain optical coherence tomography. , 2003, Optics express.

[16]  G. Fedder,et al.  Endoscopic optical coherence tomography based on a microelectromechanical mirror. , 2001, Optics letters.

[17]  B. B. Bauer,et al.  Fundamentals of acoustics , 1963 .

[18]  Xingde Li,et al.  Fiber-optic scanning two-photon fluorescence endoscope. , 2006, Optics letters.

[19]  Xingde Li,et al.  Super-Achromatic Rapid Scanning Microendoscope for Ultrahigh-Resolution OCT Imaging , 2007, IEEE Journal of Selected Topics in Quantum Electronics.