The cognitive life of mechanical molecular models.

The use of physical models of molecular structures as research tools has been central to the development of biochemistry and molecular biology. Intriguingly, it has received little attention from scholars of science. In this paper, I argue that these physical models are not mere three-dimensional representations but that they are in fact very special research tools: they are cognitive augmentations. Despite the fact that they are external props, these models serve as cognitive tools that augment and extend the modeler's cognitive capacities and performance in molecular modeling tasks. This cognitive enhancement is obtained because of the way the modeler interacts with these models, the models' materiality contributing to the solving of the molecule's structure. Furthermore, I argue that these material models and their component parts were designed, built and used specifically to serve as cognitive facilitators and cognitive augmentations.

[1]  Quentin R. Petersen,et al.  Some Reflections on the Use and Abuse of Molecular Models. , 1970 .

[2]  I. Löwy.  Models: The Third Dimension of Science , 2006 .

[3]  R. Giere,et al.  Representing with Physical Models , 2009 .

[4]  Visual Cognition: Where Cognition and Culture Meet , 2006, Philosophy of Science.

[5]  Mathias Beike,et al.  The path to the double helix , 1975, Medical History.

[6]  L. Pauling,et al.  Configurations of Polypeptide Chains With Favored Orientations Around Single Bonds: Two New Pleated Sheets. , 1951, Proceedings of the National Academy of Sciences of the United States of America.

[7]  Eric Francoeur,et al.  From model kits to interactive computer graphics , 2004 .

[8]  P. Laszlo.  Playing with Molecular Models , 2000 .

[9]  O. Ramsay,et al.  Van't Hoff - Le Bel centennial : a symposium sponsored by the Division of the History of Chemistry at the 168th meeting of the American Chemical Society, Atlantic City, N.J., Sept. 11-12, 1974 , 1975 .

[10]  P. Kleingeld,et al.  The Stanford Encyclopedia of Philosophy , 2013 .

[11]  L. Pauling,et al.  Modern Structural Chemistry. , 1956, Science.

[12]  Linus Pauling,et al.  Molecular Models of Amino Acids, Peptides, and Proteins , 1953 .

[13]  Nancy J. Nersessian,et al.  Creating Scientific Concepts , 2008 .

[14]  Mary Jo Nye,et al.  From Chemical Philosophy to Theoretical Chemistry: Dynamics of Matter and Dynamics of Disciplines, 1800-1950 , 1994 .

[15]  Richard K. Coll,et al.  The Role of Models, Mental Models and Analogies in Chemistry Teaching , 2006 .

[16]  Ursula Klein,et al.  Techniques of modelling and paper tools in classical chemistry , 1999 .

[17]  Eric Francoeur,et al.  Does the materiality of molecular models really matter , 2000 .

[18]  Deane K. Smith.  Bibliography on Molecular and Crystal Structure Models , 1960 .

[19]  Richard Edwards,et al.  Extending ourselves , 2003 .

[20]  W. L. Koltun,et al.  Precision space‐filling atomic models , 1965, Biopolymers.

[21]  R. Harré.  Models in Science. , 1978 .

[22]  David C. Gooding,et al.  Visualizing Scientific Inference , 2010, Top. Cogn. Sci..

[23]  É. Francoeur.  Molecular models and the articulation of structural constraints in chemistry , 2001 .

[24]  M. Nye.  Paper Tools and Molecular Architecture in the Chemistry of Linus Pauling , 2001 .

[25]  The Need for Better Macromolecular Models , 1960, Science.

[26]  Davis Baird,et al.  Thing Knowledge: A Philosophy of Scientific Instruments , 2004 .

[27]  Barbara Baird,et al.  Models and molecules , 1994, Nature.

[28]  Anne Walton.  Molecular and Crystal Structure Models , 1960, Nature.

[29]  D C Richardson,et al.  Looking at proteins: representations, folding, packing, and design. Biophysical Society National Lecture, 1992. , 1992, Biophysical journal.

[30]  O. Ramsay.  van't Hoff-Le Bel Centennial , 1975 .

[31]  Margaret Morrison,et al.  Models as Mediators: Perspectives on Natural and Social Science , 1999 .

[32]  Eric Francoeur,et al.  The Forgotten Tool: The Design and Use of Molecular Models , 1997 .

[33]  Lily E. Kay,et al.  The molecular vision of life : Caltech, the Rockefeller Foundation, and the rise of the new biology , 1994 .