Paired-like Homeodomain Transcription factor 2 expression by breast cancer bone marrow disseminated tumor cells is associated with early recurrent disease development
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M. Watson | R. Aft | K. Trinkaus | T. Fleming | Nupur Dasgupta | S. G. Pillai | Chidananda M. Siddappa | S. Pillai
[1] Diane Angonin,et al. Nkd1 Functions as a Passive Antagonist of Wnt Signaling , 2013, PloS one.
[2] A. Cheung,et al. Increased Expression of PITX2 Transcription Factor Contributes to Ovarian Cancer Progression , 2012, PloS one.
[3] M. Broggini,et al. Interaction between human-breast cancer metastasis and bone microenvironment through activated hepatocyte growth factor/Met and beta-catenin/Wnt pathways. , 2010, European journal of cancer.
[4] Jianhui Guo,et al. Mutations in the Human naked cuticle Homolog NKD1 Found in Colorectal Cancer Alter Wnt/Dvl/β-Catenin Signaling , 2009, PloS one.
[5] Shinichi Takano,et al. DICKKOPF‐4 and ‐2 genes are upregulated in human colorectal cancer , 2009, Cancer science.
[6] E. Peña,et al. A gene expression classifier of node-positive colorectal cancer. , 2009, Neoplasia.
[7] Marc Ladanyi,et al. WNT/TCF Signaling through LEF1 and HOXB9 Mediates Lung Adenocarcinoma Metastasis , 2009, Cell.
[8] G. Kristiansen,et al. DNA methylation of the PITX2 gene promoter region is a strong independent prognostic marker of biochemical recurrence in patients with prostate cancer after radical prostatectomy. , 2009, The Journal of urology.
[9] M. Anver,et al. Smad ubiquitination regulatory factor 2 promotes metastasis of breast cancer cells by enhancing migration and invasiveness. , 2009, Cancer research.
[10] John W. M. Martens,et al. DNA hypermethylation of PITX2 is a marker of poor prognosis in untreated lymph node-negative hormone receptor-positive breast cancer patients , 2008, Breast Cancer Research and Treatment.
[11] C. Carlberg,et al. DICKKOPF-4 is induced by TCF/β-catenin and upregulated in human colon cancer, promotes tumour cell invasion and angiogenesis and is repressed by 1α,25-dihydroxyvitamin D3 , 2008, Oncogene.
[12] R. Maestro,et al. Induction of EMT by twist proteins as a collateral effect of tumor-promoting inactivation of premature senescence. , 2008, Cancer cell.
[13] B. Amendt,et al. PITX2 and β-Catenin Interactions Regulate Lef-1 Isoform Expression , 2007, Molecular and Cellular Biology.
[14] L. Ylagan,et al. Isolation and Molecular Profiling of Bone Marrow Micrometastases Identifies TWIST1 as a Marker of Early Tumor Relapse in Breast Cancer Patients , 2007, Clinical Cancer Research.
[15] J. Foekens,et al. DNA-methylation of the homeodomain transcription factor PITX2 reliably predicts risk of distant disease recurrence in tamoxifen-treated, node-negative breast cancer patients--Technical and clinical validation in a multi-centre setting in collaboration with the European Organisation for Research and , 2007, European journal of cancer.
[16] H. Bazzi,et al. The Wnt inhibitor, Dickkopf 4, is induced by canonical Wnt signaling during ectodermal appendage morphogenesis. , 2007, Developmental biology.
[17] R. Grosschedl,et al. Lef1 is required for the transition of Wnt signaling from mesenchymal to epithelial cells in the mouse embryonic mammary gland. , 2006, Developmental biology.
[18] M. Gessler,et al. Target genes of the WNT/β‐catenin pathway in Wilms tumors , 2006 .
[19] Xianquan Zhan,et al. Novel molecular signaling and classification of human clinically nonfunctional pituitary adenomas identified by gene expression profiling and proteomic analyses. , 2005, Cancer research.
[20] R. Holcombe,et al. Wnt pathway component LEF1 mediates tumor cell invasion and is expressed in human and murine breast cancers lacking ErbB2 (her-2/neu) overexpression. , 2005, International journal of oncology.
[21] K. Pantel,et al. Detection and molecular characterisation of disseminated tumour cells: implications for anti-cancer therapy. , 2005, Biochimica et biophysica acta.
[22] T. Fehm,et al. A pooled analysis of bone marrow micrometastasis in breast cancer. , 2005, The New England journal of medicine.
[23] Paola Briata,et al. Identification of a Wnt/Dvl/β-Catenin → Pitx2 Pathway Mediating Cell-Type-Specific Proliferation during Development , 2002, Cell.
[24] I. Macdonald,et al. Metastasis: Dissemination and growth of cancer cells in metastatic sites , 2002, Nature Reviews Cancer.
[25] M. Wiesmann,et al. Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/β-catenin signaling is activated in human colon tumors , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[26] S. Braun,et al. The fate and prognostic value of occult metastatic cells in the bone marrow of patients with breast carcinoma between primary treatment and recurrence , 2001, Cancer.
[27] G. Naumov,et al. Critical steps in hematogenous metastasis: an overview. , 2001, Surgical oncology clinics of North America.
[28] H. Steinbeisser,et al. Pitx2 isoforms: involvement of Pitx2c but not Pitx2a or Pitx2b in vertebrate left–right asymmetry , 2000, Mechanisms of Development.
[29] S. Miyagawa-Tomita,et al. Mouse Pitx2 deficiency leads to anomalies of the ventral body wall, heart, extra- and periocular mesoderm and right pulmonary isomerism. , 1999, Development.
[30] C. Tabin,et al. The Transcription Factor Pitx2 Mediates Situs-Specific Morphogenesis in Response to Left-Right Asymmetric Signals , 1998, Cell.
[31] C. Croce,et al. Identification and characterization of the ARP1 gene, a target for the human acute leukemia ALL1 gene. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[32] L. Liotta,et al. General mechanisms of metastasis , 1997, Cancer.
[33] J. Carey,et al. Cloning and characterization of a novel bicoid-related homeobox transcription factor gene, RIEG, involved in Rieger syndrome , 1996, Nature Genetics.
[34] J. Folkman,et al. The role of angiogenesis in tumor growth. , 1992, Seminars in cancer biology.
[35] B. Amendt,et al. PITX2 and beta-catenin interactions regulate Lef-1 isoform expression. , 2007, Molecular and cellular biology.
[36] Norbert Graf,et al. Target genes of the WNT/beta-catenin pathway in Wilms tumors. , 2006, Genes, chromosomes & cancer.
[37] Christopher W. Wong,et al. Apoptosis: an early event in metastatic inefficiency. , 2001, Cancer research.
[38] Y. Saijoh,et al. Two-step regulation of left-right asymmetric expression of Pitx2: initiation by nodal signaling and maintenance by Nkx2. , 2001, Molecular cell.
[39] H Sommer,et al. Lack of effect of adjuvant chemotherapy on the elimination of single dormant tumor cells in bone marrow of high-risk breast cancer patients. , 2000, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[40] I. Fidler,et al. Critical determinants of cancer metastasis: rationale for therapy , 1999, Cancer Chemotherapy and Pharmacology.
[41] L. Weiss,et al. Metastatic inefficiency. , 1990, Advances in cancer research.