Preparation of Garlic Powder with High Allicin Content

Abstract Garlic powder with high allicin content was prepared using microwave-vacuum and vacuum drying as well as microencapsulation to protect alliinase activity throughout the stomach and improve the ratio of alliin transforming into allicin. The results showed that the optimal drying condition was 376.1 W for 3 min, 282.1 W for 3 min, 188 W for 9 min, and 94 W for 3 min. The thiosulfinates retention after drying was 90.2%. Following drying, the garlic powder was microencapsulated by modified fluidized bed technique. Scanning electron microscope revealed good integrity and core materials that were embedded in the microcapsules. Studies on the release kinetics of microencapsulated garlic granulates in vitro using simulated intestinal fluid indicated that release of garlic powder could be controlled in the intestine by passing stomach conditions.

[1]  Haw‐Wen Chen,et al.  Effect of garlic oil on hepatic arachidonic acid content and immune response in rats , 1998 .

[2]  M. Keusgen,et al.  Cysteine Sulfoxides and Alliinase Activity of Some Allium Species , 2000 .

[3]  Sun Min Kim,et al.  Antioxidative Activity of Sulfur-containing Flavor Compounds in Garlic , 1997 .

[4]  G. Han,et al.  A spectrophotometric method for quantitative determination of allicin and total garlic thiosulfinates. , 1995, Analytical biochemistry.

[5]  M. Kim,et al.  Alliinase‐independent Inhibition of Staphylococcus aureus B33 by Heated Garlic , 2002 .

[6]  M. Connock,et al.  Gender may affect the action of garlic oil on plasma cholesterol and glucose levels of normal subjects. , 2001, The Journal of nutrition.

[7]  C. Lii,et al.  Effects of organosulfur compounds from garlic oil on the antioxidation system in rat liver and red blood cells. , 2001, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[8]  E. Block.  The Organosulfur Chemistry of the Genus Allium – Implications for the Organic Chemistry of Sulfur , 1992 .

[9]  Saleem Ahmad,et al.  The chemistry of alkyl thiosulfinate esters. 9. Antithrombotic organosulfur compounds from garlic: structural, mechanistic, and synthetic studies , 1986 .

[10]  M. Wilchek,et al.  The mode of action of allicin: trapping of radicals and interaction with thiol containing proteins. , 1998, Biochimica et biophysica acta.

[11]  Da-Wen Sun,et al.  Dehydration of Garlic Slices by Combined Microwave-Vacuum and Air Drying , 2003 .

[12]  M. Farid,et al.  MICROWAVE VACUUM DRYING OF BANANA SLICES , 2002 .

[13]  M. Ali,,et al.  Effect of allicin from garlic powder on serum lipids and blood pressure in rats fed with a high cholesterol diet. , 2000, Prostaglandins, leukotrienes, and essential fatty acids.

[14]  T. Durance,et al.  Texture of Vacuum Microwave Dehydrated Apple Chips as Affected by Calcium Pretreatment, Vacuum Level, and Apple Variety , 2001 .

[15]  S. Pyo,et al.  Immunomodulating effect of garlic component, allicin, on murine peritoneal macrophages , 2001 .

[16]  T. Grune,et al.  Influence of Allium sativum on oxidative stress status - a clinical investigation. , 1996, Phytomedicine : international journal of phytotherapy and phytopharmacology.

[17]  Wen Cheng,et al.  Antioxidant Activity of Several Allium Members , 1998 .

[18]  M. Wilchek,et al.  Effect of Purified Allicin, the Major Ingredient ofFreshly Crushed Garlic, on Cancer Cell Proliferation , 2000, Nutrition and cancer.

[19]  D. Papadimitriou,et al.  Allicin Release under Simulated Gastrointestinal Conditions from Garlic Powder Tablets Employed in Clinical Trials on Serum Cholesterol , 2001, Planta medica.

[20]  K. Prasad,et al.  Evaluation of hydroxyl radical-scavenging property of garlic , 1996, Molecular and Cellular Biochemistry.

[21]  H. Schubert,et al.  Combined osmotic and microwave-vacuum dehydration of apples and strawberries ☆ , 2001 .