High resolution ion chamber array delivery quality assurance for robotic radiosurgery: Commissioning and validation.

PURPOSE High precision radiosurgery demands comprehensive delivery-quality-assurance techniques. The use of a liquid-filled ion-chamber-array for robotic-radiosurgery delivery-quality-assurance was investigated and validated using several test scenarios and routine patient plans. METHODS AND MATERIAL Preliminary evaluation consisted of beam profile validation and analysis of source-detector-distance and beam-incidence-angle response dependence. The delivery-quality-assurance analysis is performed in four steps: (1) Array-to-plan registration, (2) Evaluation with standard Gamma-Index criteria (local-dose-difference⩽2%, distance-to-agreement⩽2mm, pass-rate⩾90%), (3) Dose profile alignment and dose distribution shift until maximum pass-rate is found, and (4) Final evaluation with 1mm distance-to-agreement criterion. Test scenarios consisted of intended phantom misalignments, dose miscalibrations, and undelivered Monitor Units. Preliminary method validation was performed on 55 clinical plans in five institutions. RESULTS The 1000SRS profile measurements showed sufficient agreement compared with a microDiamond detector for all collimator sizes. The relative response changes can be up to 2.2% per 10cm source-detector-distance change, but remains within 1% for the clinically relevant source-detector-distance range. Planned and measured dose under different beam-incidence-angles showed deviations below 1% for angles between 0° and 80°. Small-intended errors were detected by 1mm distance-to-agreement criterion while 2mm criteria failed to reveal some of these deviations. All analyzed delivery-quality-assurance clinical patient plans were within our tight tolerance criteria. CONCLUSION We demonstrated that a high-resolution liquid-filled ion-chamber-array can be suitable for robotic radiosurgery delivery-quality-assurance and that small errors can be detected with tight distance-to-agreement criterion. Further improvement may come from beam specific correction for incidence angle and source-detector-distance response.

[1]  Subhash C. Sharma,et al.  Commissioning and acceptance testing of a CyberKnife linear accelerator , 2007, Journal of applied clinical medical physics.

[2]  Benjamin E Nelms,et al.  Moving from gamma passing rates to patient DVH-based QA metrics in pretreatment dose QA. , 2011, Medical physics.

[3]  P Francescon,et al.  Quality assurance of volumetric modulated arc therapy: evaluation and comparison of different dosimetric systems. , 2011, Medical physics.

[4]  Panayiotis Mavroidis,et al.  Characterization of a two-dimensional liquid-filled ion chamber detector array used for verification of the treatments in radiotherapy. , 2014, Medical physics.

[5]  Oliver Blanck,et al.  Film-based delivery quality assurance for robotic radiosurgery: Commissioning and validation. , 2015, Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics.

[6]  Guanghua Yan,et al.  On the sensitivity of patient‐specific IMRT QA to MLC positioning errors , 2009, Journal of applied clinical medical physics.

[7]  S Cora,et al.  Monte Carlo simulated correction factors for machine specific reference field dose calibration and output factor measurement using fixed and iris collimators on the CyberKnife system , 2012, Physics in medicine and biology.

[8]  M J Murphy,et al.  The Cyberknife: a frameless robotic system for radiosurgery. , 1997, Stereotactic and functional neurosurgery.

[9]  D Harder,et al.  Performance parameters of a liquid filled ionization chamber array. , 2013, Medical physics.

[10]  Todd Pawlicki,et al.  Cyberknife image-guided delivery and quality assurance. , 2008, International journal of radiation oncology, biology, physics.

[11]  J. Mechalakos,et al.  IMRT commissioning: multiple institution planning and dosimetry comparisons, a report from AAPM Task Group 119. , 2009, Medical physics.

[12]  Timothy C Zhu,et al.  Determination of correction factors for a 2D diode array device in MV photon beams. , 2009, Medical physics.

[13]  Weigang Hu,et al.  A spatially encoded dose difference maximal intensity projection map for patient dose evaluation: a new first line patient quality assurance tool. , 2011, Medical physics.

[14]  C. Maurer,et al.  The CyberKnife® Robotic Radiosurgery System in 2010 , 2010, Technology in cancer research & treatment.

[15]  A. Quinn CyberKnife: a robotic radiosurgery system. , 2002, Clinical journal of oncology nursing.

[16]  Charlie Ma,et al.  Robotic radiosurgery system patient‐specific QA for extracranial treatments using the planar ion chamber array and the cylindrical diode array , 2015, Journal of applied clinical medical physics.

[17]  K Poels,et al.  Real time tracking in liver SBRT: comparison of CyberKnife and Vero by planning structure-based γ-evaluation and dose-area-histograms , 2016, Physics in medicine and biology.

[18]  Fujio Araki,et al.  Angular dependence correction of MatriXX and its application to composite dose verification , 2012, Journal of applied clinical medical physics.

[19]  Yolande Lievens,et al.  Time and motion study of radiotherapy delivery: Economic burden of increased quality assurance and IMRT. , 2009, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[20]  A. Chalkley,et al.  Evaluation of a synthetic single-crystal diamond detector for relative dosimetry measurements on a CyberKnife. , 2014, The British journal of radiology.

[21]  Thomas Lacornerie,et al.  Characterization of Recombination Effects in a Liquid Ionization Chamber Used for the Dosimetry of a Radiosurgical Accelerator , 2014, Journal of visualized experiments : JoVE.

[22]  Christos Antypas,et al.  Performance evaluation of a CyberKnife® G4 image-guided robotic stereotactic radiosurgery system , 2008, Physics in medicine and biology.

[23]  Xiaodong Wu,et al.  Report of AAPM TG 135: quality assurance for robotic radiosurgery. , 2011, Medical physics.

[24]  B Poppe,et al.  On the sensitivity of common gamma-index evaluation methods to MLC misalignments in Rapidarc quality assurance. , 2013, Medical physics.