The Central Role of CD4+ T Cells in the Antitumor Immune Response
暂无分享,去创建一个
C. Lowenstein | D. Pardoll | H. Levitsky | Drew Pardoll | R. Hayashi | Kenneth Hung | Robert Hayashi | Anne Lafond-Walker | Charles Lowenstein | Hyam Levitsky | A. Lafond-Walker | Kenneth Hung
[1] A. Sher,et al. IL-10 synergizes with IL-4 and transforming growth factor-beta to inhibit macrophage cytotoxic activity. , 1992, Journal of immunology.
[2] E. Jaffee,et al. Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[3] I. Fidler,et al. Role of nitric oxide in lysis of tumor cells by cytokine-activated endothelial cells. , 1991, Cancer research.
[4] P. Robbins,et al. Human tumor antigens recognized by T cells. , 1996, Current opinion in immunology.
[5] P. Greenberg,et al. Therapy of disseminated murine leukemia with cyclophosphamide and immune Lyt-1+,2- T cells. Tumor eradication does not require participation of cytotoxic T cells , 1985, The Journal of experimental medicine.
[6] S. Ostrand-Rosenberg,et al. Abrogation of tumorigenicity by MHC class II antigen expression requires the cytoplasmic domain of the class II molecule. , 1991, Journal of immunology.
[7] A. Sher,et al. The microbicidal activity of interferon‐γ‐treated macrophages against Trypanosoma cruzi involves an L‐arginine‐dependent, nitrogen oxide‐mediated mechanism inhibitable by interleukin‐10 and transforming growth factor‐β , 1992, European journal of immunology.
[8] T. Mosmann,et al. Two types of murine helper T cell clone. II. Delayed-type hypersensitivity is mediated by TH1 clones. , 1987, Journal of immunology.
[9] F. Liew,et al. Tumour necrosis factor (TNF-α) in leishmaniasis. II, TNF-α-induced macrophage leishmanicidal activity is mediated by nitric oxide from L-arginine , 1990 .
[10] F. Marshall,et al. Bioactivity of autologous irradiated renal cell carcinoma vaccines generated by ex vivo granulocyte-macrophage colony-stimulating factor gene transfer. , 1997, Cancer research.
[11] S. Moncada,et al. Macrophage killing of Leishmania parasite in vivo is mediated by nitric oxide from L-arginine. , 1990, Journal of immunology.
[12] R. Fernandez-Botran,et al. Lymphokine-mediated regulation of the proliferative response of clones of T helper 1 and T helper 2 cells , 1988, The Journal of experimental medicine.
[13] R. Locksley,et al. Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets , 1989, The Journal of experimental medicine.
[14] D. Pardoll. A new look for the 1990s , 1994, Nature.
[15] C. Lowenstein,et al. Nitric oxide inhibits viral replication in murine myocarditis. , 1996, The Journal of clinical investigation.
[16] P. Greenberg,et al. Requirement for recognition of class II molecules and processed tumor antigen for optimal generation of syngeneic tumor-specific class I-restricted CTL. , 1986, Journal of immunology.
[17] J. Mcgregor,et al. Nitric oxide synthesis contributes to IL-2-induced antitumor responses against intraperitoneal Meth A tumor. , 1995, Journal of immunology.
[18] D. Longo,et al. Immunization with granulocyte-macrophage colony-stimulating factor-transduced, but not B7-1-transduced, lymphoma cells primes idiotype-specific T cells and generates potent systemic antitumor immunity. , 1996, Journal of immunology.
[19] A. Sher,et al. Downregulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni , 1991, The Journal of experimental medicine.
[20] R. Coffman,et al. Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens , 1988, The Journal of experimental medicine.
[21] C. Nathan,et al. Nitric oxide. A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells , 1989, The Journal of experimental medicine.
[22] I. Fidler,et al. Direct correlation between expression of endogenous inducible nitric oxide synthase and regression of M5076 reticulum cell sarcoma hepatic metastases in mice treated with liposomes containing lipopeptide CGP 31362. , 1995, Cancer research.
[23] R. Locksley,et al. Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism , 1990, The Journal of experimental medicine.
[24] F. Finkelman,et al. Effects of interleukin 12 on immune responses and host protection in mice infected with intestinal nematode parasites , 1994, The Journal of experimental medicine.
[25] E. Goldwasser,et al. Anti-proliferative effect of IFN-gamma in immune regulation. II. IFN-gamma inhibits the proliferation of murine bone marrow cells stimulated with IL-3, IL-4, or granulocyte-macrophage colony-stimulating factor. , 1988, Journal of immunology.
[26] W. Samlowski,et al. Macrophage nitric oxide synthesis delays progression of ultraviolet light-induced murine skin cancers. , 1993, Cancer research.
[27] W. Paul,et al. Interleukin 4 is important in protective immunity to a gastrointestinal nematode infection in mice. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[28] S. Rosenberg,et al. Identification of Tyrosinase-related Protein 2 as a Tumor Rejection Antigen for the B16 Melanoma , 1997, The Journal of experimental medicine.
[29] I. Charles,et al. Altered immune responses in mice lacking inducible nitric oxide synthase , 1995, Nature.
[30] R. Locksley,et al. CD4+ effector cells default to the Th2 pathway in interferon gamma- deficient mice infected with Leishmania major , 1994, The Journal of experimental medicine.
[31] R. Locksley,et al. Production of interferon gamma, interleukin 2, interleukin 4, and interleukin 10 by CD4+ lymphocytes in vivo during healing and progressive murine leishmaniasis. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[32] Kathleen R. Cho,et al. Engineering an intracellular pathway for major histocompatibility complex class II presentation of antigens. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[33] R. Coffman,et al. Two types of mouse helper T-cell clone Implications for immune regulation. , 1987, Immunology today.
[34] T. Mosmann,et al. Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones , 1989, The Journal of experimental medicine.
[35] M. Dinauer,et al. Absence of Respiratory Burst in X-linked Chronic Granulomatous Disease Mice Leads to Abnormalities in Both Host Defense and Inflammatory Response to Aspergillus fumigatus , 1997, The Journal of experimental medicine.
[36] T. Mak,et al. CD8 is needed for development of cytotoxic T but not helper T cells , 1991, Cell.
[37] T. Evans,et al. Effect of in vivo inhibition of nitric oxide production in murine leishmaniasis. , 1993, Journal of immunology.
[38] P. Hodgkin,et al. IL-5-deficient mice have a developmental defect in CD5+ B-1 cells and lack eosinophilia but have normal antibody and cytotoxic T cell responses. , 1996, Immunity.
[39] C. Cross,et al. Formation of Reactive Nitrogen Species during Peroxidase-catalyzed Oxidation of Nitrite , 1997, The Journal of Biological Chemistry.
[40] T. Eisenstein,et al. Immunosuppression induced by nitric oxide and its inhibition by interleukin‐4 , 1992, European journal of immunology.
[41] C. Nathan,et al. Inhibition of tumor cell ribonucleotide reductase by macrophage-derived nitric oxide , 1991, The Journal of experimental medicine.
[42] I. Fidler,et al. Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates metastasis by K-1735 murine melanoma cells , 1995, The Journal of experimental medicine.
[43] T. Gajewski,et al. Anti-proliferative effect of IFN-gamma in immune regulation. I. IFN-gamma inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones. , 1988, Journal of immunology.
[44] W. Chan,et al. Macrophage activation by interferon‐γ from host‐protective T cells is inhibited by interleukin (IL) 3 and IL 4 produced by disease‐promoting T cells in leishmaniasis , 1989, European journal of immunology.
[45] Martin Bachmann,et al. Disruption of the murine IL-4 gene blocks Th2 cytokine responses , 1993, Nature.
[46] T. Mosmann,et al. Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies , 1987, The Journal of experimental medicine.
[47] F. Finkelman,et al. Anti-cytokine antibodies as carrier proteins. Prolongation of in vivo effects of exogenous cytokines by injection of cytokine-anti-cytokine antibody complexes. , 1993, Journal of immunology.
[48] F. Finkelman,et al. The Importance of Th2 Cytokines in Protective Immunity to Nematodes , 1992, Immunological reviews.
[49] P. Leder,et al. An eosinophil-dependent mechanism for the antitumor effect of interleukin-4. , 1992, Science.
[50] F. Liew,et al. Tumor necrosis factor-alpha synergizes with IFN-gamma in mediating killing of Leishmania major through the induction of nitric oxide. , 1990, Journal of immunology.
[51] I. Fidler. Biological behavior of malignant melanoma cells correlated to their survival in vivo. , 1975, Cancer research.
[52] P. Bruggen,et al. Human tumor antigens recognized by T lymphocytes , 1996, The Journal of experimental medicine.
[53] R. Locksley,et al. Murine cutaneous leishmaniasis: susceptibility correlates with differential expansion of helper T-cell subsets. , 1987, Annales de l'Institut Pasteur. Immunology.
[54] M. Salter,et al. A possible novel pathway of regulation by murine T helper type‐2 (Th2) cells of a Th1 cell activity via the modulation of the induction of nitric oxide synthase on macrophages , 1991, European journal of immunology.
[55] M. Schilham,et al. Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4 , 1991, Nature.
[56] A. Bradley,et al. Multiple defects of immune cell function in mice with disrupted interferon-gamma genes. , 1993, Science.
[57] T. Mosmann,et al. IL-10 inhibits cytokine production by activated macrophages. , 1991, Journal of immunology.
[58] G. Freeman,et al. Constitutive expression of B7 restores immunogenicity of tumor cells expressing truncated major histocompatibility complex class II molecules. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[59] S. Reed,et al. T-cell and cytokine responses in leishmaniasis. , 1993, Current opinion in immunology.
[60] I. G. Young,et al. Molecular cloning, nucleotide sequence, and expression of the gene encoding human eosinophil differentiation factor (interleukin 5). , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[61] A. Kelso,et al. Interleukin-4 but not gamma interferon production correlates with the severity of murine cutaneous leishmaniasis , 1993, Infection and immunity.
[62] Richard A. Flavell,et al. Help for cytotoxic-T-cell responses is mediated by CD40 signalling , 1998, Nature.
[63] Polly Matzinger,et al. A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell , 1998, Nature.
[64] H. Kita,et al. Ligation of the beta2 integrin triggers activation and degranulation of human eosinophils. , 1998, American journal of respiratory cell and molecular biology.
[65] J. Albina,et al. Activated murine macrophages induce apoptosis in tumor cells through nitric oxide-dependent or -independent mechanisms. , 1994, Cancer research.
[66] M. Belosevic,et al. Administration of monoclonal anti-IFN-gamma antibodies in vivo abrogates natural resistance of C3H/HeN mice to infection with Leishmania major. , 1989, Journal of immunology.
[67] Y. Buchmüller‐Rouiller,et al. Journal of Leukocyte Biology 49:73-82 (1991) Killing of Leishmania Parasites in Activated Murine Macrophages is Based on an L-Arginine-Dependent Process That Produces Nitrogen Derivatives , 2022 .
[68] R. Locksley,et al. Leishmania promastigotes evade interleukin 12 (IL-12) induction by macrophages and stimulate a broad range of cytokines from CD4+ T cells during initiation of infection , 1994, The Journal of experimental medicine.
[69] D. Pardoll,et al. Treatment of established renal cancer by tumor cells engineered to secrete interleukin-4. , 1991, Science.
[70] F. Luscinskas,et al. IL-4 induces adherence of human eosinophils and basophils but not neutrophils to endothelium. Association with expression of VCAM-1. , 1992, Journal of immunology.
[71] S. Galli,et al. Ultrastructural immunogold localization of tumor necrosis factor-alpha to the matrix compartment of eosinophil secondary granules in patients with idiopathic hypereosinophilic syndrome. , 1993, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
[72] D. Wong,et al. Human eosinophils can express the cytokines tumor necrosis factor-alpha and macrophage inflammatory protein-1 alpha. , 1993, The Journal of clinical investigation.
[73] C. Bucana,et al. In vivo modulation of macrophage tumoricidal activity by oral administration of the liposome-encapsulated macrophage activator CGP 19835A. , 1994, Cancer research.
[74] T. Mosmann,et al. IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells. , 1991, Journal of immunology.
[75] S. Moncada,et al. Resistance to Leishmania major infection correlates with the induction of nitric oxide synthase in murine macrophages , 1991, European journal of immunology.
[76] C. Bogdan,et al. Tissue expression of inducible nitric oxide synthase is closely associated with resistance to Leishmania major , 1994, The Journal of experimental medicine.
[77] Stephen P. Schoenberger,et al. T-cell help for cytotoxic T lymphocytes is mediated by CD40–CD40L interactions , 1998, Nature.
[78] D. Pardoll. Tumour antigens. A new look for the 1990s. , 1994, Nature.
[79] R. Steinman,et al. Identification of proliferating dendritic cell precursors in mouse blood , 1992, The Journal of experimental medicine.
[80] E. Jaffee,et al. Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens. , 1994, Science.
[81] R. Coffman,et al. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. , 1986, Journal of immunology.
[82] P. Dri,et al. Human eosinophil peroxidase enhances tumor necrosis factor and hydrogen peroxide release by human monocyte‐derived macrophages , 1995, European journal of immunology.
[83] D. Pardoll,et al. In vivo priming of two distinct antitumor effector populations: the role of MHC class I expression , 1994, The Journal of experimental medicine.
[84] T. Mak,et al. CD8 is needed for development of cytotoxic T cells but not helper T cells. , 1991, Cell.
[85] T. Mosmann,et al. Heterogeneity of mouse helper T cells. Evidence from bulk cultures and limiting dilution cloning for precursors of Th1 and Th2 cells. , 1990, Journal of immunology.
[86] P. Linsley,et al. IL-10 inhibits macrophage costimulatory activity by selectively inhibiting the up-regulation of B7 expression. , 1993, Journal of immunology.
[87] A. Sher,et al. IL-10 inhibits parasite killing and nitrogen oxide production by IFN-gamma-activated macrophages. , 1992, Journal of immunology.
[88] T. Fahey,et al. Macrophage inflammatory protein 1 modulates macrophage function. , 1992, Journal of immunology.
[89] Y. Vodovotz,et al. Mechanism of suppression of nitric oxide synthase expression by interleukin‐4 in primary mouse macrophages , 1994, Journal of leukocyte biology.
[90] M. Meltzer,et al. Activated macrophages destroy intracellular Leishmania major amastigotes by an L-arginine-dependent killing mechanism. , 1990, Journal of immunology.
[91] W. Samlowski,et al. Induction of iron-derived EPR signals in murine cancers by nitric oxide. Evidence for multiple intracellular targets. , 1994, The Journal of biological chemistry.
[92] H. Chapman,et al. Macrophage tumor killing: influence of the local environment. , 1977, Science.
[93] R. Steinman,et al. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor , 1992, The Journal of experimental medicine.
[94] S. Klebanoff,et al. Augmentation of spontaneous macrophage-mediated cytolysis by eosinophil peroxidase , 1982, The Journal of experimental medicine.
[95] A. Sher,et al. Interleukin 10 inhibits macrophage microbicidal activity by blocking the endogenous production of tumor necrosis factor alpha required as a costimulatory factor for interferon gamma-induced activation. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[96] I. Fidler,et al. Inverse correlation between expression of inducible nitric oxide synthase activity and production of metastasis in K-1735 murine melanoma cells. , 1994, Cancer research.
[97] S. Moncada,et al. Production of nitric oxide and superoxide by activated macrophages and killing of Leishmania major , 1994, European journal of immunology.
[98] J. Tschopp,et al. Melanoma Cell Expression of Fas(Apo-1/CD95) Ligand: Implications for Tumor Immune Escape , 1996, Science.
[99] R. Coffman,et al. IL-4 induces a Th2 response in Leishmania major-infected mice. , 1992, Journal of immunology.
[100] S. Ostrand-Rosenberg,et al. Invariant chain alters the malignant phenotype of MHC class II+ tumor cells. , 1992, Journal of immunology.