Obesity and head and neck cancer risk: a mendelian randomization study

[1]  G. Davey Smith,et al.  Evaluating the effect of metabolic traits on oral and oropharyngeal cancer risk using Mendelian randomization , 2023, eLife.

[2]  S. Larsson,et al.  Causal role of high body mass index in multiple chronic diseases: a systematic review and meta-analysis of Mendelian randomization studies , 2021, BMC Medicine.

[3]  E. Giovannucci,et al.  The Role of Mendelian Randomization Studies in Deciphering the Effect of Obesity on Cancer. , 2021, Journal of the National Cancer Institute.

[4]  A. Jemal,et al.  Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries , 2021, CA: a cancer journal for clinicians.

[5]  J. Tyrrell,et al.  Does Obesity Cause Thyroid Cancer? A Mendelian Randomization Study , 2020, The Journal of clinical endocrinology and metabolism.

[6]  Xin-hua Liang,et al.  Obesity: An emerging driver of head and neck cancer. , 2019, Life sciences.

[7]  Hongbing Shen,et al.  Body mass index and the risk of head and neck cancer in the Chinese population. , 2019, Cancer epidemiology.

[8]  S. Siddharth,et al.  Adiponectin, Obesity, and Cancer: Clash of the Bigwigs in Health and Disease , 2019, International journal of molecular sciences.

[9]  F. Greten,et al.  Modulating inflammation for cancer therapy , 2019, The Journal of experimental medicine.

[10]  C. Mantzoros,et al.  Obesity and cancer risk: Emerging biological mechanisms and perspectives. , 2019, Metabolism: clinical and experimental.

[11]  Gheyath K Nasrallah,et al.  Adipose tissue dysfunction in cancer cachexia , 2018, Journal of cellular physiology.

[12]  Amy Y. Chen,et al.  Epidemiology and Demographics of the Head and Neck Cancer Population. , 2018, Oral and maxillofacial surgery clinics of North America.

[13]  G. Frühbeck,et al.  Adipokine dysregulation and adipose tissue inflammation in human obesity , 2018, European journal of clinical investigation.

[14]  G. Davey Smith,et al.  Reading Mendelian randomisation studies: a guide, glossary, and checklist for clinicians , 2018, British Medical Journal.

[15]  B. Neale,et al.  Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases , 2018, Nature Genetics.

[16]  F. Greten,et al.  Cell plasticity in epithelial homeostasis and tumorigenesis , 2017, Nature Cell Biology.

[17]  Pantelis G Bagos,et al.  Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus , 2017, Nature Communications.

[18]  Andrew D. Johnson,et al.  Edinburgh Research Explorer Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits , 2022 .

[19]  Fernando Pires Hartwig,et al.  Robust inference in summary data Mendelian randomization via the zero modal pleiotropy assumption , 2017, bioRxiv.

[20]  G. Davey Smith,et al.  Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator , 2016, Genetic epidemiology.

[21]  E. Riboli,et al.  Anthropometry and head and neck cancer:a pooled analysis of cohort data. , 2015, International journal of epidemiology.

[22]  G. Davey Smith,et al.  Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression , 2015, International journal of epidemiology.

[23]  Ross M. Fraser,et al.  Genetic studies of body mass index yield new insights for obesity biology , 2015, Nature.

[24]  Y. Tong,et al.  Obesity and Risk of Thyroid Cancer: Evidence from a Meta-Analysis of 21 Observational Studies , 2015, Medical science monitor : international medical journal of experimental and clinical research.

[25]  C. Abnet,et al.  A Prospective Cohort Study of Body Size and Risk of Head and Neck Cancers in the NIH–AARP Diet and Health Study , 2014, Cancer Epidemiology, Biomarkers & Prevention.

[26]  A. Butterworth,et al.  Mendelian Randomization Analysis With Multiple Genetic Variants Using Summarized Data , 2013, Genetic epidemiology.

[27]  S. Buys,et al.  Tobacco, alcohol, body mass index, physical activity, and the risk of head and neck cancer in the prostate, lung, colorectal, and ovarian (PLCO) cohort , 2013, Head & neck.

[28]  Amy Y. Chen,et al.  Prospective Studies of Body Mass Index with Head and Neck Cancer Incidence and Mortality , 2012, Cancer Epidemiology, Biomarkers & Prevention.

[29]  Rudolph L. Leibel,et al.  Obesity and leptin resistance: distinguishing cause from effect , 2010, Trends in Endocrinology & Metabolism.

[30]  S. Ebrahim,et al.  'Mendelian randomization': can genetic epidemiology contribute to understanding environmental determinants of disease? , 2003, International journal of epidemiology.

[31]  Q. Wei,et al.  Association of pretreatment body mass index with risk of head and neck cancer: a large single-center study. , 2021, American journal of cancer research.

[32]  S. Theocharis,et al.  The role of adipokines in the establishment and progression of head and neck neoplasms. , 2018, Current medicinal chemistry.

[33]  D. Croteau-Chonka,et al.  New genetic loci link adipose and insulin biology to body fat distribution , 2015 .

[34]  Scott M Langevin,et al.  Obesity and head and neck cancer risk and survival by human papillomavirus serology , 2014, Cancer Causes & Control.

[35]  R. N. Mody,et al.  Estimation of serum leptin in oral squamous cell carcinoma. , 2010, Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology.

[36]  George Davey Smith,et al.  Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology , 2008, Statistics in medicine.

[37]  Hilde van der Togt,et al.  Publisher's Note , 2003, J. Netw. Comput. Appl..

[38]  S. Taylor Head and neck cancer. , 1991, Cancer chemotherapy and biological response modifiers.