Endovascular therapy for acute ischemic stroke.

Publisher Summary This chapter presents an overview of catheter-based strategies for the treatment of acute ischemic stroke. New techniques and recent advances are highlighted such as a mechanical thrombectomy device for restoration of blood flow in the neurovasculature. Endovascular therapy is an effective alternative for recanalization of major vessel occlusion and has become a reality in the armamentarium of stroke treatment. Site-specific intra-arterial delivery of thrombolytic agents has enabled recanalization of anterior and posterior circulation lesions. Mechanical techniques for clot disruption have resulted in increased vessel recanalization rates and reduced hemorrhage rates concomitant with reduced doses of thrombolytic agents. Improvement in patient selection, refinement in technology, and the incorporation of endovascular teams at stroke centers drives the utility of these techniques forward.

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