The Alzheimer’s Disease-Associated Presenilins Are Differentially Phosphorylated Proteins Located Predominantly within the Endoplasmic Reticulum
暂无分享,去创建一个
D. Selkoe | P. Fraser | C. Haass | J. Walter | M. Podlisny | R. Prior | A. Capell | P. St. George Hyslop | B. Pesold | A. Schindzielorz | J. Grünberg | Dennis J. Selkoe | Marcia B. Podlisny
[1] C. van Broeckhoven,et al. The presenilin genes: a new gene family involved in Alzheimer disease pathology. , 1996, Human molecular genetics.
[2] C. Haass. Presenile because of presenilin: the presenilin genes and early onset Alzheimer's disease , 1996, Current opinion in neurology.
[3] M. Adams,et al. Complete analysis of the presenilin 1 gene in early onset Alzheimer's disease , 1996, Neuroreport.
[4] Y. Sakaki,et al. Regional and cellular presenilin 1 gene expression in human and rat tissues. , 1996, Biochemical and biophysical research communications.
[5] B. Hyman,et al. Alzheimer–associated presenilins 1 and 2 : Neuronal expression in brain and localization to intracellular membranes in mammalian cells , 1996, Nature Medicine.
[6] J. Gilbert,et al. Mutation analysis of presenilin 1 gene in Alzheimer's disease , 1996, The Lancet.
[7] Brian J Cummings,et al. Image analysis of β-amyloid load in Alzheimer's disease and relation to dementia severity , 1995, The Lancet.
[8] M. Adams,et al. A mutation in Alzheimer's disease destroying a splice acceptor site in the presenilin-1 gene , 1995, Neuroreport.
[9] G. Thomas,et al. Intracellular trafficking of furin is modulated by the phosphorylation state of a casein kinase II site in its cytoplasmic tail. , 1995, The EMBO journal.
[10] B. Dubois,et al. Mutations of the presenilin I gene in families with early-onset Alzheimer's disease. , 1995, Human molecular genetics.
[11] M. Cruts,et al. Molecular genetic analysis of familial early-onset Alzheimer's disease linked to chromosome 14q24.3. , 1995, Human molecular genetics.
[12] T. L. Furminger,et al. Breakpoint characterization of the ret/PTC oncogene in human papillary thyroid carcinoma. , 1995, Human molecular genetics.
[13] D. Selkoe,et al. The Swedish mutation causes early-onset Alzheimer's disease by β-secretase cleavage within the secretory pathway , 1995, Nature Medicine.
[14] Iva Greenwald,et al. Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene , 1995, Nature.
[15] J. Growdon,et al. Familial Alzheimer's chromosome 14 mutations , 1995, Nature Medicine.
[16] J. Rommens,et al. Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene , 1995, Nature.
[17] E M Wijsman,et al. A familial Alzheimer's disease locus on chromosome 1 , 1995, Science.
[18] G. Schellenberg,et al. Candidate gene for the chromosome 1 familial Alzheimer's disease locus , 1995, Science.
[19] D. Price,et al. Amyloid beta amyloidosis in Alzheimer's disease. , 1995, Current opinion in neurology.
[20] D. Pollen,et al. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease , 1995, Nature.
[21] A D Roses,et al. Apolipoprotein E and Alzheimer disease. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[22] M. Adams,et al. The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families , 1995, Nature Genetics.
[23] S. Squazzo,et al. Evidence that production and release of amyloid beta-protein involves the endocytic pathway. , 1994, The Journal of biological chemistry.
[24] D. Selkoe,et al. Mutations associated with a locus for familial Alzheimer's disease result in alternative processing of amyloid beta-protein precursor. , 1994, The Journal of biological chemistry.
[25] Richard L. Huganir,et al. Glutamate receptor phosphorylation and synaptic plasticity , 1994, Current Opinion in Neurobiology.
[26] S. Younkin,et al. An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants. , 1994, Science.
[27] D. Y. Thomas,et al. Calnexin: a membrane-bound chaperone of the endoplasmic reticulum. , 1994, Trends in biochemical sciences.
[28] A. Robitzki,et al. Recombinant human casein kinase II , 1994 .
[29] D. Selkoe,et al. Normal and abnormal biology of the beta-amyloid precursor protein. , 1994, Annual review of neuroscience.
[30] A. Robitzki,et al. Recombinant human casein kinase II. A study with the complete set of subunits (alpha, alpha' and beta), site-directed autophosphorylation mutants and a bicistronically expressed holoenzyme. , 1994, European journal of biochemistry.
[31] D. Selkoe,et al. Cellular processing of β-amyloid precursor protein and the genesis of amyloid β-peptide , 1993, Cell.
[32] J. Growdon,et al. Activation of protein kinase C inhibits cellular production of the amyloid beta-protein. , 1993, The Journal of biological chemistry.
[33] M. Mullan,et al. Genetics and molecular advances in Alzheimer's disease , 1993, Trends in Neurosciences.
[34] P. Greengard,et al. Protein phosphorylation inhibits production of Alzheimer amyloid beta/A4 peptide. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[35] R. Pepperkok,et al. Cell biological studies with monoclonal and polyclonal antibodies against human casein kinase II subunit beta demonstrate participation of the kinase in mitogenic signaling. , 1993, The Journal of biological chemistry.
[36] S. Younkin,et al. Release of excess amyloid beta protein from a mutant amyloid beta protein precursor. , 1993, Science.
[37] F. Crawford,et al. Genetic and molecular advances in Alzheimer's disease. , 1993, Trends in neurosciences.
[38] D. Selkoe,et al. Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide. , 1993, Cell.
[39] O. Issinger,et al. Casein kinases: pleiotropic mediators of cellular regulation. , 1993, Pharmacology & therapeutics.
[40] D. Selkoe,et al. Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-protein production , 1992, Nature.
[41] C. Broeckhoven,et al. Mapping of a gene predisposing to early–onset Alzheimer's disease to chromosome 14q24.3 , 1992, Nature Genetics.
[42] D. Pollen,et al. Genetic evidence for a novel familial Alzheimer's disease locus on chromosome 14 , 1992, Nature Genetics.
[43] J. Weber,et al. Genetic linkage evidence for a familial Alzheimer's disease locus on chromosome 14. , 1992, Science.
[44] J. Growdon,et al. Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors. , 1992, Science.
[45] S. L'Hernault,et al. Mutation of a putative sperm membrane protein in Caenorhabditis elegans prevents sperm differentiation but not its associated meiotic divisions , 1992, The Journal of cell biology.
[46] D. Selkoe,et al. Cellular processing of β-amyloid precursor protein and the genesis of amyloid β-peptide , 1993, Cell.
[47] D. Selkoe,et al. Homology of the amyloid beta protein precursor in monkey and human supports a primate model for beta amyloidosis in Alzheimer's disease. , 1991, The American journal of pathology.
[48] M. Pericak-Vance,et al. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease , 1991, Nature.
[49] T. Hunter,et al. Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates. , 1991, Methods in enzymology.
[50] P. Greengard,et al. Processing of Alzheimer beta/A4 amyloid precursor protein: modulation by agents that regulate protein phosphorylation. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[51] Andreas Weidemann,et al. Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein , 1989, Cell.
[52] K. Grzeschik,et al. The precursor of Alzheimer??s disease amyloid A4 protein resembles a cell-surface receptor , 1987 .
[53] W. Huttner. Protein tyrosine sulfation , 1987 .
[54] P. Vassalli,et al. Lectin-binding sites as markers of Golgi subcompartments: proximal-to- distal maturation of oligosaccharides , 1983, The Journal of cell biology.
[55] G K Gilbert,et al. THE ORIGIN OF HYPOTHESES, ILLUSTRATED BY THE DISCUSSION OF A TOPOGRAPHIC PROBLEM. , 1896, Science.