Toward New Vital Signs: Tools and Methods for Dense Physiologic Data Capture, Analysis, and Decision Support in Critical Care

SIMON (Signal Interpretation and MONitoring) continuously collects, permanently stores, and processes bedside medical device data. Since 1998 SIMON has monitored over 3500 trauma intensive care unit (TICU) patients, representing approximately 250,000 hours of continuous monitoring and two billion data points, and is currently operational on all 14 TICU beds at Vanderbilt University Medical Center. This repository of dense physiologic data (heart rate, arterial, pulmonary, central venous, intracranial, and cerebral perfusion pressures, arterial and venous oxygen saturations, and other parameters sampled second-by-second) supports research to identify “new vital signs” features of patient physiology only observable through dense data capture and analysis more predictive of patient status than current measures. SIMON’s alerting and reporting capabilities, including web-based display, sentinel event notification via alphanumeric pagers, and daily summary reports of vital sign statistics, allow these discoveries to be rapidly tested and implemented in a working clinical environment. This

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