A Secreted Tyrosine Kinase Acts in the Extracellular Environment

[1]  Weiguo Feng,et al.  A morpholino‐based screen to identify novel genes involved in craniofacial morphogenesis , 2013, Developmental dynamics : an official publication of the American Association of Anatomists.

[2]  K. Pawłowski,et al.  A Novel Predicted Calcium-Regulated Kinase Family Implicated in Neurological Disorders , 2012, PloS one.

[3]  J. Dixon,et al.  Crystal structure of the Golgi casein kinase , 2013, Proceedings of the National Academy of Sciences.

[4]  R. Zeller,et al.  The hedgehog target Vlk genetically interacts with Gli3 to regulate chondrocyte differentiation during mouse long bone development. , 2013, Differentiation; research in biological diversity.

[5]  J. Dixon,et al.  Secreted protein kinases. , 2013, Trends in biochemical sciences.

[6]  G. Lenz,et al.  Purinergic signaling in glioma progression. , 2013, Advances in experimental medicine and biology.

[7]  V. Vogel,et al.  Extracellular Phosphorylation and Phosphorylated Proteins: Not Just Curiosities But Physiologically Important , 2012, Science Signaling.

[8]  D. Kiel,et al.  Clinical review: Genome-wide association studies of skeletal phenotypes: what we have learned and where we are headed. , 2012, The Journal of clinical endocrinology and metabolism.

[9]  Lisa N Kinch,et al.  Secreted Kinase Phosphorylates Extracellular Proteins That Regulate Biomineralization , 2012, Science.

[10]  S. Eschrich,et al.  Phosphoproteomics identifies driver tyrosine kinases in sarcoma cell lines and tumors. , 2012, Cancer research.

[11]  Y. Liu,et al.  Inactivation of a Novel FGF23 Regulator, FAM20C, Leads to Hypophosphatemic Rickets in Mice , 2012, PLoS genetics.

[12]  J. Asara,et al.  Determining In Vivo Phosphorylation Sites Using Mass Spectrometry , 2012, Current protocols in molecular biology.

[13]  A. Mogilner,et al.  Microtubule and cortical forces determine platelet size during vascular platelet production , 2012, Nature Communications.

[14]  Bin Zhang,et al.  PhosphoSitePlus: a comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouse , 2011, Nucleic Acids Res..

[15]  Alexandra Naba,et al.  Overview of the matrisome--an inventory of extracellular matrix constituents and functions. , 2012, Cold Spring Harbor perspectives in biology.

[16]  M. Tamura,et al.  Acidic bone matrix proteins and their roles in calcification. , 2012, Frontiers in bioscience.

[17]  Z. Werb,et al.  Extracellular matrix degradation and remodeling in development and disease. , 2011, Cold Spring Harbor perspectives in biology.

[18]  S. Brunak,et al.  SignalP 4.0: discriminating signal peptides from transmembrane regions , 2011, Nature Methods.

[19]  Li Li,et al.  Global defects in collagen secretion in a Mia3/TANGO1 knockout mouse , 2011, The Journal of cell biology.

[20]  J. Becker,et al.  Identification and functional analysis of novel genes expressed in the Anterior Visceral Endoderm. , 2011, The International journal of developmental biology.

[21]  B. Snel,et al.  Tyrosine Phosphorylation Profiling in FGF-2 Stimulated Human Embryonic Stem Cells , 2011, PloS one.

[22]  G. Bu,et al.  Two structural and functional domains of MESD required for proper folding and trafficking of LRP5/6. , 2011, Structure.

[23]  Jian Yu,et al.  Survey of Tyrosine Kinase Signaling Reveals ROS Kinase Fusions in Human Cholangiocarcinoma , 2011, PloS one.

[24]  M. Smyth,et al.  Extracellular adenosine triphosphate and adenosine in cancer , 2010, Oncogene.

[25]  G. Bu,et al.  NMR structure note: solution structure of the core domain of MESD that is essential for proper folding of LRP5/6 , 2010, Journal of biomolecular NMR.

[26]  Markus M. Rinschen,et al.  Quantitative phosphoproteomic analysis reveals vasopressin V2-receptor–dependent signaling pathways in renal collecting duct cells , 2010, Proceedings of the National Academy of Sciences.

[27]  S. Mohammed,et al.  Exploring the human leukocyte phosphoproteome using a microfluidic reversed-phase-TiO2-reversed-phase high-performance liquid chromatography phosphochip coupled to a quadrupole time-of-flight mass spectrometer. , 2010, Analytical chemistry.

[28]  R. Flaumenhaft,et al.  Platelet alpha-granules: basic biology and clinical correlates. , 2009, Blood reviews.

[29]  Jens Leipziger,et al.  ATP release from non-excitable cells , 2009, Purinergic Signalling.

[30]  P. Neumann,et al.  Crystal structure and functional analysis of the protein disulfide isomerase-related protein ERp29. , 2009, Journal of molecular biology.

[31]  H. Kiyonari,et al.  Short limbs, cleft palate, and delayed formation of flat proliferative chondrocytes in mice with targeted disruption of a putative protein kinase gene, Pkdcc (AW548124) , 2009, Developmental dynamics : an official publication of the American Association of Anatomists.

[32]  木下 将樹 The novel protein kinase Vlk is essential for stromal function of mesenchymal cells , 2009 .

[33]  F. Di Virgilio,et al.  Increased Level of Extracellular ATP at Tumor Sites: In Vivo Imaging with Plasma Membrane Luciferase , 2008, PloS one.

[34]  Steven P Gygi,et al.  Signaling networks assembled by oncogenic EGFR and c-Met , 2008, Proceedings of the National Academy of Sciences.

[35]  J. Raffetto,et al.  Matrix metalloproteinases and their inhibitors in vascular remodeling and vascular disease. , 2008, Biochemical pharmacology.

[36]  S. Gygi,et al.  Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain. , 2008, Journal of proteome research.

[37]  P. Jurasz,et al.  Role of metalloproteinases in platelet function. , 2008, Thrombosis research.

[38]  Laura A. Sullivan,et al.  Global Survey of Phosphotyrosine Signaling Identifies Oncogenic Kinases in Lung Cancer , 2007, Cell.

[39]  Paul Horton,et al.  Nucleic Acids Research Advance Access published May 21, 2007 WoLF PSORT: protein localization predictor , 2007 .

[40]  W. Bode,et al.  X-ray Structure of Human proMMP-1 NEW INSIGHTS INTO PROCOLLAGENASE ACTIVATION AND COLLAGEN BINDING* , 2005 .

[41]  Z. Werb,et al.  Altered endochondral bone development in matrix metalloproteinase 13-deficient mice , 2004, Development.

[42]  G. Sheldrick,et al.  Mapping of a Substrate Binding Site in the Protein Disulfide Isomerase-related Chaperone Wind Based on Protein Function and Crystal Structure* , 2004, Journal of Biological Chemistry.

[43]  Ping Chen,et al.  Overriding Imatinib Resistance with a Novel ABL Kinase Inhibitor , 2004, Science.

[44]  J. Kornhauser,et al.  PhosphoSite: A bioinformatics resource dedicated to physiological protein phosphorylation , 2004, Proteomics.

[45]  Jie J. Zheng,et al.  The LRP5 High-Bone-Mass G171V Mutation Disrupts LRP5 Interaction with Mesd , 2004, Molecular and Cellular Biology.

[46]  S. Hanks,et al.  Genomic analysis of the eukaryotic protein kinase superfamily: a perspective , 2003, Genome Biology.

[47]  R. Flaumenhaft,et al.  Protein kinase C Mediates Translocation of Type II Phosphatidylinositol 5-Phosphate 4-Kinase Required for Platelet α-Granule Secretion* , 2003, The Journal of Biological Chemistry.

[48]  J. Hsieh,et al.  Mesd Encodes an LRP5/6 Chaperone Essential for Specification of Mouse Embryonic Polarity , 2003, Cell.

[49]  R. Flaumenhaft,et al.  Protein kinase C mediates translocation of type II phosphatidylinositol 5-phosphate 4-kinase required for platelet alpha-granule secretion. , 2003, The Journal of biological chemistry.

[50]  D. Sheppard,et al.  Mapping of the cryptic integrin-binding site in osteopontin suggests a new mechanism by which thrombin can regulate inflammation and tissue repair. , 2000, Trends in cardiovascular medicine.

[51]  J. Hartwig,et al.  Blood Platelets Are Assembled Principally at the Ends of Proplatelet Processes Produced by Differentiated Megakaryocytes , 1999, The Journal of cell biology.

[52]  S. Israels,et al.  Platelet dense granules: structure, function and implications for haemostasis. , 1999, Thrombosis research.

[53]  C. Foster,et al.  Binding of a thrombin receptor tethered ligand analogue to human platelet thrombin receptor. , 1997, Molecular pharmacology.

[54]  C. López-Otín,et al.  The helping hand of collagenase-3 (MMP-13): 2.7 A crystal structure of its C-terminal haemopexin-like domain. , 1996, Journal of molecular biology.

[55]  D. Greenspan,et al.  Bone Morphogenetic Protein-1: The Type I Procollagen C-Proteinase , 1996, Science.

[56]  H. R. Faber,et al.  1.8 A crystal structure of the C-terminal domain of rabbit serum haemopexin. , 1995, Structure.

[57]  T. Hunter,et al.  The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification 1 , 1995, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[58]  Peter Harrison,et al.  Platelet a-granules , 1993 .

[59]  Paul J. Harrison,et al.  Platelet alpha-granules. , 1993, Blood reviews.

[60]  W. Fantl,et al.  Signalling by receptor tyrosine kinases. , 1993, Annual review of biochemistry.

[61]  R. Swank,et al.  Lumenal location of the microsomal beta-glucuronidase-egasyn complex , 1987, The Journal of cell biology.

[62]  J. L. Gordon Extracellular ATP: effects, sources and fate. , 1986, The Biochemical journal.

[63]  D. Prockop Mutations in collagen genes. Consequences for rare and common diseases. , 1985, The Journal of clinical investigation.

[64]  M. M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. , 1976, Analytical biochemistry.