Experimental estimation of the structure of endothely of parodont vesselsin the dynamics of the inflammatory process

The results of the evaluation of the endothelium structure of the periodontal vessels of the upper and lower jaw of rats in norm and in the modeling of periodontitis were presented. From the first day, changes in the cytostructure of cells affect the length, thickness of endotheliocytes and pericytes, the number of mitochondria, the Golgi complex, the reticulum of the endothelium, and the amount of heterochromatin in the nucleus. Complex structural changes trigger the reactions of the microcirculatory bed of periodontal tissues with a violation of the rheological properties of the blood, the formation of exudate and an inflammatory cellular infiltrate. Beginning from the 14th day, proliferative changes appear more pronounced in the vessels of the upper jaw, which ensure, by the 30th day of parodontitis mo- deling, the preservation of the regulation of the tone of blood vessels, the emigration of blood cells and the activation of local proliferation processes.

[1]  О О Мартышин Метаболический синдром и ожирение: нужна ли биопсия печени? , 2017 .

[2]  А. Г. Сирак,et al.  Особенности васкуляризации пульпы зуба у больных пародонтитом , 2017 .

[3]  Степанов Роман Иванович,et al.  Восприятие читателем угрозы в информационном пространстве: результаты экспериментального исследования , 2017 .

[4]  Yali Hou,et al.  Human gingival fibroblasts induced and differentiated into vascular endothelial‐like cells , 2016, Development, Growth and Differentiation.

[5]  В. А. Жулинский,et al.  Внедрение интерактивной формы обучения для студентов кафедры патологической физиологии , 2016 .

[6]  Шабанов Петр Дмитриевич,et al.  Кисспептины в физиологии и патологии полового развития - новые диагностические и терапевтические возможности , 2014 .

[7]  Е. Л. Золотухина Стволовые клетки и перспективы их применения в стоматологии и челюстно-лицевой хирургии , 2014 .

[8]  Д. К. Гайнуллина,et al.  Оксид азота в эндотелии сосудов: регуляция продукции и механизмы действия , 2013 .

[9]  H. Goodis,et al.  Dental clinics of North America. , 2012, Dental clinics of North America.

[10]  P. Vanhoutte,et al.  Endothelium‐mediated control of vascular tone: COX‐1 and COX‐2 products , 2011, British journal of pharmacology.

[11]  M. Makuuchi,et al.  A mouse model of vascular injury that induces rapid onset of medial cell apoptosis followed by reproducible neointimal hyperplasia. , 2000, Journal of molecular and cellular cardiology.

[12]  D. Celermajer,et al.  Endothelial dysfunction: does it matter? Is it reversible? , 1997, Journal of the American College of Cardiology.