N-Acetyltransferase-2 (NAT2) phenotype is influenced by genotype-environment interaction in Ethiopians
暂无分享,去创建一个
[1] A. Hoeflich,et al. Partial phenotype conversion and differential trait response to conditions of husbandry in mice , 2017, Journal of Comparative Physiology B.
[2] B. Ali,et al. Studies on N‐Acetyltransferase (NAT2) Genotype Relationships in Emiratis: Confirmation of the Existence of Phenotype Variation among Slow Acetylators , 2017, Annals of human genetics.
[3] M. Lhermitte,et al. Prevention of isoniazid toxicity by NAT2 genotyping in Senegalese tuberculosis patients , 2016, Toxicology reports.
[4] M. Lee,et al. Genome-wide association and replication study of anti-tuberculosis drugs-induced liver toxicity , 2016, BMC Genomics.
[5] W. Amogne,et al. SLCO1B1 Gene Variations Among Tanzanians, Ethiopians, and Europeans: Relevance for African and Worldwide Precision Medicine. , 2016, Omics : a journal of integrative biology.
[6] P. Anzenbacher,et al. Human gut microbiota plays a role in the metabolism of drugs. , 2016, Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia.
[7] A. Sanchez‐Mazas,et al. Variation in NAT2 acetylation phenotypes is associated with differences in food-producing subsistence modes and ecoregions in Africa , 2015, BMC Evolutionary Biology.
[8] Jing Shi,et al. Susceptibility of N-acetyltransferase 2 slow acetylators to antituberculosis drug-induced liver injury: a meta-analysis. , 2015, Pharmacogenomics.
[9] M. Bortolini,et al. NAT2 gene diversity and its evolutionary trajectory in the Americas , 2015, The Pharmacogenomics Journal.
[10] C. Capelli,et al. Exploring the relationship between lifestyles, diets and genetic adaptations in humans , 2015, BMC Genetics.
[11] R. Altman,et al. PharmGKB summary: very important pharmacogene information for N-acetyltransferase 2. , 2014, Pharmacogenetics and genomics.
[12] M. Ingelman-Sundberg,et al. High CYP2A6 enzyme activity as measured by a caffeine test and unique distribution of CYP2A6 variant alleles in Ethiopian population. , 2014, Omics : a journal of integrative biology.
[13] E. Sim,et al. Arylamine N-acetyltransferases: from drug metabolism and pharmacogenetics to drug discovery , 2014, British journal of pharmacology.
[14] Lawrence A. David,et al. Diet rapidly and reproducibly alters the human gut microbiome , 2013, Nature.
[15] H. McIlleron,et al. Serum drug concentrations predictive of pulmonary tuberculosis outcomes. , 2013, The Journal of infectious diseases.
[16] I. Kawase,et al. NAT2 genotype guided regimen reduces isoniazid-induced liver injury and early treatment failure in the 6-month four-drug standard treatment of tuberculosis: A randomized controlled trial for pharmacogenetics-based therapy , 2012, European Journal of Clinical Pharmacology.
[17] L. Bertilsson,et al. Pharmacogenetic and pharmacokinetic aspects of CYP3A induction by efavirenz in HIV patients , 2012, The Pharmacogenomics Journal.
[18] Shakir Ali,et al. Prevalence of poor and rapid metabolizers of drugs metabolized by CYP2B6 in North Indian population residing in Indian national capital territory , 2012, SpringerPlus.
[19] L. Bertilsson,et al. Comparison of N‐Acetyltransferase‐2 Enzyme Genotype‐Phenotype and Xanthine Oxidase Enzyme Activity Between Swedes and Koreans , 2012, Journal of clinical pharmacology.
[20] M. Hutz,et al. Accuracy of NAT2 SNP genotyping panels to infer acetylator phenotypes in African, Asian, Amerindian and admixed populations. , 2012, Pharmacogenomics.
[21] S. Xie,et al. NAT2 polymorphisms and susceptibility to anti-tuberculosis drug-induced liver injury: a meta-analysis [Review article]. , 2012, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.
[22] L. Lindquist,et al. Pharmacogenetic & Pharmacokinetic Biomarker for Efavirenz Based ARV and Rifampicin Based Anti-TB Drug Induced Liver Injury in TB-HIV Infected Patients , 2011, PloS one.
[23] S. Janković,et al. N‐acetyltransferase‐2 (NAT2) Gene Polymorphisms and Enzyme Activity in Serbs: Unprecedented High Prevalence of Rapid Acetylators in a White Population , 2011, Journal of clinical pharmacology.
[24] A. Sabbagh,et al. Arylamine N-Acetyltransferase 2 (NAT2) Genetic Diversity and Traditional Subsistence: A Worldwide Population Survey , 2011, PloS one.
[25] U. Diczfalusy,et al. Sex and CYP3A5 genotype influence total CYP3A activity: high CYP3A activity and a unique distribution of CYP3A5 variant alleles in Ethiopians , 2011, The Pharmacogenomics Journal.
[26] G. Perry,et al. Evolutionary adaptations to dietary changes. , 2010, Annual review of nutrition.
[27] J. Muscat,et al. Comparison of CYP1A2 and NAT2 phenotypes between black and white smokers. , 2008, Biochemical Pharmacology.
[28] A. Novelletto,et al. Multiple Advantageous Amino Acid Variants in the NAT2 Gene in Human Populations , 2008, PloS one.
[29] E. García-Martín. Interethnic and intraethnic variability of NAT2 single nucleotide polymorphisms. , 2008, Current drug metabolism.
[30] H. Halkin,et al. VKORC1 Asp36Tyr warfarin resistance marker is common in Ethiopian individuals. , 2008, Blood.
[31] A. Aseffa,et al. Anti-Tuberculosis Therapy-Induced Hepatotoxicity among Ethiopian HIV-Positive and Negative Patients , 2008, PloS one.
[32] A. Langaney,et al. Worldwide distribution of NAT2 diversity: Implications for NAT2 evolutionary history , 2008, BMC Genetics.
[33] E. Heyer,et al. Population genetic diversity of the NAT2 gene supports a role of acetylation in human adaptation to farming in Central Asia , 2008, European Journal of Human Genetics.
[34] P. V. Helden,et al. The influence of dose and N-acetyltransferase-2 (NAT2) genotype and phenotype on the pharmacokinetics and pharmacodynamics of isoniazid , 2007, European Journal of Clinical Pharmacology.
[35] T. Brüning,et al. Concordance between the deduced acetylation status generated by high-speed: real-time PCR based NAT2 genotyping of seven single nucleotide polymorphisms and human NAT2 phenotypes determined by a caffeine assay. , 2007, Clinica chimica acta; international journal of clinical chemistry.
[36] R. Straka,et al. Discordance Between N‐acetyltransferase 2 Phenotype and Genotype in a Population of Hmong Subjects , 2006, Journal of clinical pharmacology.
[37] U. Fuhr,et al. Should We Use N-Acetyltransferase Type 2 Genotyping To Personalize Isoniazid Doses? , 2005, Antimicrobial Agents and Chemotherapy.
[38] S. Selinski,et al. Re-investigation of the concordance of human NAT2 phenotypes and genotypes , 2005, Archives of Toxicology.
[39] M. Ingelman-Sundberg,et al. Genetic polymorphism of CYP1A2 in Ethiopians affecting induction and expression: characterization of novel haplotypes with single-nucleotide polymorphisms in intron 1. , 2003, Molecular pharmacology.
[40] M. Ingelman-Sundberg,et al. Xanthine oxidase activity is influenced by environmental factors in Ethiopians , 2003, European Journal of Clinical Pharmacology.
[41] M. Ingelman-Sundberg,et al. Evidence for environmental influence on CYP2D6-catalysed debrisoquine hydroxylation as demonstrated by phenotyping and genotyping of Ethiopians living in Ethiopia or in Sweden. , 2002, Pharmacogenetics.
[42] R. MacArthur,et al. Acetylator Phenotype and Genotype in HIV‐Infected Patients with and without Sulfonamide Hypersensitivity , 2002, Journal of clinical pharmacology.
[43] B. Leyland-Jones,et al. Stability of 5-acetamido-6-formylamino-3-methyluracil in buffers and urine. , 2002, Journal of pharmaceutical and biomedical analysis.
[44] A. Seow,et al. Correlation between acetylation phenotype and genotype in Chinese women , 2000, European Journal of Clinical Pharmacology.
[45] C. Alm,et al. Evaluation of caffeine as an in vivo probe for CYP1A2 using measurements in plasma, saliva, and urine. , 2000, Therapeutic drug monitoring.
[46] P. Beaune,et al. Evaluation of caffeine as a test drug for CYP1A2, NAT2 and CYP2E1 phenotyping in man by in vivo versus in vitro correlations. , 1996, Pharmacogenetics (London).
[47] G. Tucker,et al. Testing for bimodality in frequency distributions of data suggesting polymorphisms of drug metabolism--hypothesis testing. , 1989, British journal of clinical pharmacology.
[48] Jeremy K Nicholson,et al. Gut microbiome interactions with drug metabolism, efficacy, and toxicity. , 2017, Translational research : the journal of laboratory and clinical medicine.
[49] M. Doll,et al. Accuracy of various human NAT2 SNP genotyping panels to infer rapid, intermediate and slow acetylator phenotypes. , 2012, Pharmacogenomics.
[50] M. Banerjee,et al. Arylamine N-acetyltransferase 2 polymorphism in the ethnic populations of South India. , 2003, International journal of molecular medicine.
[51] T. Buclin,et al. NAT2 and CYP1A2 phenotyping with caffeine: head-to-head comparison of AFMU vs. AAMU in the urine metabolite ratios. , 2003, British journal of clinical pharmacology.