Texture Analysis for Automatic Segmentation of Intervertebral Disks of Scoliotic Spines From MR Images

This paper presents a unified framework for automatic segmentation of intervertebral disks of scoliotic spines from different types of magnetic resonance (MR) image sequences. The method exploits a combination of statistical and spectral texture features to discriminate closed regions representing intervertebral disks from background in MR images of the spine. Specific texture features are evaluated for three types of MR sequences acquired in the sagittal plane: 2-D spin echo, 3-D multiecho data image combination, and 3-D fast imaging with steady state precession. A total of 22 texture features (18 statistical and 4 spectral) are extracted from every closed region obtained from an automatic segmentation procedure based on the watershed approach. The feature selection step based on principal component analysis and clustering process permit to decide among all the extracted features which ones resulted in the highest rate of good classification. The proposed method is validated using a supervised k-nearest-neighbor classifier on 505 MR images coming from three different scoliotic patients and three different MR acquisition protocols. Results suggest that the selected texture features and classification can contribute to solve the problem of oversegmentation inherent to existing automatic segmentation methods by successfully discriminating intervertebral disks from the background on MRI of scoliotic spines.

[1]  F Eckstein,et al.  Computer-aided three dimensional assessment of knee-joint cartilage with magnetic resonance imaging. , 1996, Clinical biomechanics.

[2]  G J Barker,et al.  Quantification of spinal cord atrophy from magnetic resonance images via a B‐spline active surface model , 2002, Magnetic resonance in medicine.

[3]  Serge J. Belongie,et al.  Normalized cuts in 3-D for spinal MRI segmentation , 2004, IEEE Transactions on Medical Imaging.

[4]  Christopher J. Taylor,et al.  Automatic Measurement of Vertebral Shape using Active Shape Models , 1996, BMVC.

[5]  Luc Vincent,et al.  Watersheds in Digital Spaces: An Efficient Algorithm Based on Immersion Simulations , 1991, IEEE Trans. Pattern Anal. Mach. Intell..

[6]  R P Velthuizen,et al.  MRI segmentation: methods and applications. , 1995, Magnetic resonance imaging.

[7]  Jose Luis Patino,et al.  Fuzzy relations applied to minimize over segmentation in watershed algorithms , 2005, Pattern Recognit. Lett..

[8]  M. Modic,et al.  Magnetic resonance imaging of the cervical spine: technical and clinical observations. , 1983, AJR. American journal of roentgenology.

[9]  L. Schad,et al.  MR tissue characterization of intracranial tumors by means of texture analysis. , 1993, Magnetic resonance imaging.

[10]  Bram van Ginneken,et al.  Segmentation of anatomical structures in chest radiographs using supervised methods: a comparative study on a public database , 2006, Medical Image Anal..

[11]  Ross T. Whitaker,et al.  Case study: an evaluation of user-assisted hierarchical watershed segmentation , 2005, Medical Image Anal..

[12]  Farida Cheriet,et al.  Watershed Segmentation of Intervertebral Disk and Spinal Canal from MRI Images , 2007, ICIAR.

[13]  Mary M. Galloway,et al.  Texture analysis using gray level run lengths , 1974 .

[14]  David A. Clausi,et al.  Image segmentation using MRI vertebral cross-sections , 2001, Canadian Conference on Electrical and Computer Engineering 2001. Conference Proceedings (Cat. No.01TH8555).

[15]  R P Velthuizen,et al.  MRI: stability of three supervised segmentation techniques. , 1993, Magnetic resonance imaging.

[16]  Shigeo Abe DrEng Pattern Classification , 2001, Springer London.

[17]  Isabelle Bloch,et al.  opologically controlled segmentation of 3D magnetic resonance images of the head by using morphological operators , 2003, Pattern Recognit..

[18]  H. Levine Medical Imaging , 2010, Annals of Biomedical Engineering.

[19]  Christos Davatzikos,et al.  PROBABILISTIC SEGMENTATION OF BRAIN TUMORS BASED ON MULTI-MODALITY MAGNETIC RESONANCE IMAGES , 2007, 2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro.

[20]  Anil K. Jain,et al.  Statistical Pattern Recognition: A Review , 2000, IEEE Trans. Pattern Anal. Mach. Intell..

[21]  Mariano Alcañiz Raya,et al.  Hierarchical image segmentation using a correspondence with a tree model , 2004, Pattern Recognit..

[22]  Fakhri Karray,et al.  Fuzzy integral based region merging for watershed image segmentation , 2001, 10th IEEE International Conference on Fuzzy Systems. (Cat. No.01CH37297).

[23]  Andrew G. Dempster,et al.  Noise sensitivity of watershed segmentation for different connectivity: experimental study , 2004 .

[24]  Say Wei Foo,et al.  Watershed-presegmented snake for boundary detection and tracking of left ventricle in echocardiographic images , 2006, IEEE Transactions on Information Technology in Biomedicine.

[25]  Paul Suetens,et al.  Minimal Shape and Intensity Cost Path Segmentation , 2007, IEEE Transactions on Medical Imaging.

[26]  W. Eric L. Grimson,et al.  Adaptive Segmentation of MRI Data , 1995, CVRMed.

[27]  Rafael C. González,et al.  Digital image processing using MATLAB , 2006 .

[28]  A L Martel,et al.  A 3D MRI sequence for computer assisted surgery of the lumbar spine , 2001, Physics in medicine and biology.

[29]  R Kerslake,et al.  Assessment of 3-dimensional magnetic resonance imaging fast low angle shot images for computer assisted spinal surgery. , 1998, Computer aided surgery : official journal of the International Society for Computer Aided Surgery.

[30]  Damien Galanaud,et al.  Noninvasive diagnostic assessment of brain tumors using combined in vivo MR imaging and spectroscopy , 2006, Magnetic resonance in medicine.

[31]  Stanley C. Fralick,et al.  Nonparametric Bayes-risk estimation , 1971, IEEE Trans. Inf. Theory.

[32]  J R Hesselink,et al.  MR imaging of the spine: recent advances in pulse sequences and special techniques. , 1994, AJR. American journal of roentgenology.

[33]  Bram van Ginneken,et al.  Detection of coronary calcifications from computed tomography scans for automated risk assessment of coronary artery disease. , 2007, Medical physics.

[34]  Valerie Duay,et al.  Relative anatomical location for statistical non-parametric brain tissue classification in MR images , 2001, Proceedings 2001 International Conference on Image Processing (Cat. No.01CH37205).

[35]  Petra Perner,et al.  Data Mining - Concepts and Techniques , 2002, Künstliche Intell..

[36]  Christian W A Pfirrmann,et al.  Imaging of patellar cartilage with a 2D multiple-echo data image combination sequence. , 2005, AJR. American journal of roentgenology.

[37]  Milan Sonka,et al.  "Handbook of Medical Imaging, Volume 2. Medical Image Processing and Analysis " , 2000 .

[38]  Robert M. Haralick,et al.  Textural Features for Image Classification , 1973, IEEE Trans. Syst. Man Cybern..

[39]  N. Otsu A threshold selection method from gray level histograms , 1979 .

[40]  Zhigang Peng,et al.  Automated Vertebra Detection and Segmentation from the Whole Spine MR Images , 2005, 2005 IEEE Engineering in Medicine and Biology 27th Annual Conference.

[41]  Robert Marti,et al.  A Novel Breast Tissue Density Classification Methodology , 2008, IEEE Transactions on Information Technology in Biomedicine.

[42]  R. Grebe,et al.  Quantitative evaluation of trabecular bone structure by calcaneus MR images texture analysis of healthy volunteers and osteoporotic subjects , 2001, 2001 Conference Proceedings of the 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[43]  George C. Kagadis,et al.  Improving brain tumor characterization on MRI by probabilistic neural networks and non-linear transformation of textural features , 2008, Comput. Methods Programs Biomed..

[44]  L O Hall,et al.  Review of MR image segmentation techniques using pattern recognition. , 1993, Medical physics.

[45]  Peter E. Hart,et al.  Nearest neighbor pattern classification , 1967, IEEE Trans. Inf. Theory.

[46]  Arvid Lundervold,et al.  Multispectral analysis of the brain using magnetic resonance imaging , 1994, IEEE Trans. Medical Imaging.

[47]  Tingting Mu,et al.  Classification of Breast Masses Using Selected Shape, Edge-sharpness, and Texture Features with Linear and Kernel-based Classifiers , 2008, Journal of Digital Imaging.

[48]  Farida Cheriet,et al.  Automatic Closed Edge Detection Using Level Lines Selection , 2007, ICIAR.

[49]  Alejandro F. Frangi,et al.  Active shape model segmentation with optimal features , 2002, IEEE Transactions on Medical Imaging.