Intraoperative ultrasound guided breast surgery: paving the way for personalized surgery.

Since the first publication in 1988 about intraoperative ultrasound (IOUS) guided surgery, where Schwartz and colleagues (1) found that ultrasound (US) was an accurate and effective tool for localizing breast masses visualized by US and thus facilitating the surgical excision, multiple manuscripts have reported the use of IOUS to guide BCS in non-palpable breast cancer (2-4).

[1]  I. Rubio,et al.  Margins in breast conserving surgery: A practice-changing process. , 2016, European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.

[2]  S. Meijer,et al.  Intraoperative Ultrasound Guidance in Breast-Conserving Surgery Improves Cosmetic Outcomes and Patient Satisfaction: Results of a Multicenter Randomized Controlled Trial (COBALT) , 2015, Annals of Surgical Oncology.

[3]  Juan Pablo Salazar,et al.  Intraoperative Ultrasound-Guided Lumpectomy Versus Mammographic Wire Localization for Breast Cancer Patients After Neoadjuvant Treatment , 2015, Annals of Surgical Oncology.

[4]  Seema A. Khan,et al.  Society of Surgical Oncology–American Society for Radiation Oncology Consensus Guideline on Margins for Breast-Conserving Surgery With Whole-Breast Irradiation in Stages I and II Invasive Breast Cancer , 2014, Annals of Surgical Oncology.

[5]  J. Dai,et al.  Intraoperative Ultrasound Guidance Is Associated with Clear Lumpectomy Margins for Breast Cancer: A Systematic Review and Meta-Analysis , 2013, PloS one.

[6]  M. Ramos,et al.  Ultrasound-guided excision combined with intraoperative assessment of gross macroscopic margins decreases the rate of reoperations for non-palpable invasive breast cancer. , 2013, Breast.

[7]  M. Ahmed,et al.  Intra-operative ultrasound versus wire-guided localization in the surgical management of non-palpable breast cancers: systematic review and meta-analysis , 2013, Breast Cancer Research and Treatment.

[8]  S. Meijer,et al.  Intraoperative ultrasound guidance for palpable breast cancer excision (COBALT trial): a multicentre, randomised controlled trial. , 2013, The Lancet. Oncology.

[9]  S. Meijer,et al.  Excessive Resections in Breast‐Conserving Surgery: A Retrospective Multicentre Study , 2011, The breast journal.

[10]  I. Ashkenazi,et al.  Resection Margins in Ultrasound-Guided Breast-Conserving Surgery , 2011, Annals of Surgical Oncology.

[11]  Kent Westbrook,et al.  Ten-Year Experience with Hematoma-Directed Ultrasound-Guided (HUG) Breast Lumpectomy , 2010, Annals of Surgical Oncology.

[12]  D. Krag,et al.  Intraoperative Ultrasound Versus Mammographic Needle Localization for Ductal Carcinoma In Situ , 2009, Annals of Surgical Oncology.

[13]  Peter A Ubel,et al.  Effect of esthetic outcome after breast-conserving surgery on psychosocial functioning and quality of life. , 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[14]  S. Meijer,et al.  Ultrasound-guided lumpectomy of nonpalpable breast cancer versus wire-guided resection: A randomized clinical trial , 2002, Annals of Surgical Oncology.

[15]  C. Kaufman,et al.  Intraoperative ultrasound facilitates surgery for early breast cancer , 2002, Annals of Surgical Oncology.

[16]  I. Rubio,et al.  Surgical use of breast ultrasound. , 2003, The Surgical clinics of North America.

[17]  B. Goldberg,et al.  Ultrasonography: an alternative to x-ray-guided needle localization of nonpalpable breast masses. , 1988, Surgery.