EMG signal morphology in essential tremor and Parkinson's disease

The aim of this work was to differentiate patients with essential tremor from patients with Parkinson's disease. The electromyographic signal from the biceps brachii muscle was measured during isometric tension from 17 patients with essential tremor, 35 patients with Parkinson's disease, and 40 healthy controls. The EMG signals were high pass filtered and divided to smaller segments from which histograms were calculated using 200 histogram bins. EMG signal histogram shape was analysed with a feature dimension reduction method, the principal component analysis, and the shape parameters were used to differentiate between different patient groups. The height of the histogram and the side difference between left and right hand were the best discriminators between essential tremor and Parkinson's disease groups. With this method, it was possible to discriminate 13/17 patients with essential tremor from 26/35 patients with Parkinson's disease and 14/17 patients with essential tremor from 29/40 healthy controls.

[1]  J. Jankovic.  Parkinson’s disease: clinical features and diagnosis , 2008, Journal of Neurology, Neurosurgery, and Psychiatry.

[2]  Mika P. Tarvainen,et al.  An advanced detrending method with application to HRV analysis , 2002, IEEE Transactions on Biomedical Engineering.

[3]  R. Benecke,et al.  Value of combined midbrain sonography, olfactory and motor function assessment in the differential diagnosis of early Parkinson's disease , 2012, Journal of Neurology, Neurosurgery & Psychiatry.

[4]  I. Tarkka,et al.  Analysis of surface EMG signal morphology in Parkinson's disease , 2007, Physiological measurement.

[5]  M. Tarvainen,et al.  Novel parameters of surface EMG in patients with Parkinson's disease and healthy young and old controls. , 2009, Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology.

[6]  D. Vaillancourt,et al.  Combined measures of movement and force variability distinguish Parkinson’s disease from essential tremor , 2011, Clinical Neurophysiology.

[7]  Oren Cohen,et al.  Rest tremor in patients with essential tremor: prevalence, clinical correlates, and electrophysiologic characteristics. , 2003, Archives of neurology.

[8]  E. Katunina,et al.  [Epidemiology of Parkinson's disease]. , 2013, Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova.

[9]  V. Demarin,et al.  Distinguishing Parkinson’s disease and essential tremor with transcranial sonography , 2009, Acta neurologica Scandinavica.

[10]  G. Deuschl,et al.  A new diagnostic test to distinguish tremulous Parkinson's disease from advanced essential tremor , 2011, Movement disorders : official journal of the Movement Disorder Society.

[11]  M. L. Fravolini,et al.  Comparison of two neural network classifiers in the differential diagnosis of essential tremor and Parkinson’s disease by 123I-FP-CIT brain SPECT , 2010, European Journal of Nuclear Medicine and Molecular Imaging.

[12]  J. Schulz,et al.  Long-term EMG recordings differentiate between parkinsonian and essential tremor , 2008, Journal of Neurology.

[13]  A. Hossen,et al.  Discrimination of Parkinsonian tremor from essential tremor by implementation of a wavelet-based soft-decision technique on EMG and accelerometer signals , 2010, Biomed. Signal Process. Control..

[14]  E. Louis,et al.  How common is the most common adult movement disorder? Update on the worldwide prevalence of essential tremor , 2010, Movement disorders : official journal of the Movement Disorder Society.

[15]  A. Cherubini,et al.  Synchronous pattern distinguishes resting tremor associated with essential tremor from rest tremor of Parkinson's disease. , 2011, Parkinsonism & related disorders.

[16]  Christian R Baumann,et al.  Epidemiology, diagnosis and differential diagnosis in Parkinson's disease tremor. , 2012, Parkinsonism & related disorders.