Targeting autophagy in atherosclerosis: Advances and therapeutic potential of natural bioactive compounds from herbal medicines and natural products.
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Tao Wang | Yi Zhang | Jing-ya Ruan | Sijian Wang | Jiayan Shen | Bona Jia | Mengyang Liu | J. Ruan | Yiwen Zhang | Ruolan Yuan | Miao Liu
[1] W. Gillanders,et al. Use of acidic nanoparticles to rescue macrophage lysosomal dysfunction in atherosclerosis , 2022, Autophagy.
[2] A. Cuervo,et al. Chaperone-mediated autophagy protects against atherosclerosis , 2022, Autophagy.
[3] G. Pasterkamp,et al. Protective role of chaperone-mediated autophagy against atherosclerosis , 2022, Proceedings of the National Academy of Sciences of the United States of America.
[4] Renzheng Chen,et al. Pitavastatin activates mitophagy to protect EPC proliferation through a calcium-dependent CAMK1-PINK1 pathway in atherosclerotic mice , 2022, Communications Biology.
[5] K. Rayner,et al. Autophagy Is Differentially Regulated in Leukocyte and Nonleukocyte Foam Cells During Atherosclerosis , 2022, Circulation research.
[6] Hongshan Chen,et al. Curcumin ameliorates inflammation in atherogenesis by enhancing autophagy via the TFEB–p300–BRD4 axis , 2021, Acta Pharmaceutica Sinica B.
[7] Yun Zhang,et al. Deficient Chaperone-Mediated Autophagy Promotes Inflammation and Atherosclerosis , 2021, Circulation research.
[8] Zhiyong Wu,et al. Baicalin alleviates Mycoplasma gallisepticum-induced oxidative stress and inflammation via modulating NLRP3 inflammasome-autophagy pathway. , 2021, International immunopharmacology.
[9] P. Libby,et al. Targeting inflammation in atherosclerosis — from experimental insights to the clinic , 2021, Nature Reviews Drug Discovery.
[10] Shanshan Liu,et al. Smooth muscle-specific HuR knockout induces defective autophagy and atherosclerosis , 2021, Cell Death & Disease.
[11] F. Bosco,et al. Oxidative Stress Triggers Defective Autophagy in Endothelial Cells: Role in Atherothrombosis Development , 2021, Antioxidants.
[12] XiuTeng Zhou,et al. Puerarin Attenuates LPS-Induced Inflammatory Responses and Oxidative Stress Injury in Human Umbilical Vein Endothelial Cells through Mitochondrial Quality Control , 2021, Oxidative medicine and cellular longevity.
[13] P. Libby,et al. New Insights Into Plaque Erosion as a Mechanism of Acute Coronary Syndromes. , 2021, JAMA.
[14] Yan Zhang,et al. Naringenin promotes cell autophagy to improve high-fat-diet-induced atherosclerosis in ApoE-/- mice , 2021, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.
[15] Sathish Kumar Jayapal,et al. Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019 , 2020, Journal of the American College of Cardiology.
[16] H. Kwon,et al. Extract of high hydrostatic pressure-treated danshen (Salvia miltiorrhiza) ameliorates atherosclerosis via autophagy induction , 2020, BMB reports.
[17] Chengzhi Lu,et al. Oxidized LDL Causes Endothelial Apoptosis by Inhibiting Mitochondrial Fusion and Mitochondria Autophagy , 2020, Frontiers in Cell and Developmental Biology.
[18] M. Dai,et al. Paeonol inhibits apoptosis of vascular smooth muscle cells via up-regulation of autophagy by activating class III PI3K/Beclin-1 signaling pathway. , 2020, Life sciences.
[19] K. Gao,et al. Bazedoxifene inhibits PDGF-BB induced VSMC phenotypic switch via regulating the autophagy level. , 2020, Life sciences.
[20] D. Liao,et al. Celastrol suppresses lipid accumulation through LXRα/ABCA1 signaling pathway and autophagy in vascular smooth muscle cells. , 2020, Biochemical and biophysical research communications.
[21] Xiaoyan Zhu,et al. Fucoidan Inhibits NLRP3 Inflammasome Activation by Enhancing p62/SQSTM1-Dependent Selective Autophagy to Alleviate Atherosclerosis , 2020, Oxidative medicine and cellular longevity.
[22] Si Jin,et al. Salidroside-Mediated Autophagic Targeting of Active Src and Caveolin-1 Suppresses Low-Density Lipoprotein Transcytosis across Endothelial Cells , 2020, Oxidative medicine and cellular longevity.
[23] Zhicong Zeng,et al. Berberine Attenuates Arterial Plaque Formation in Atherosclerotic Rats with Damp-Heat Syndrome via Regulating Autophagy , 2020, Drug design, development and therapy.
[24] Z. Yue,et al. The P2RY12 receptor promotes VSMC-derived foam cell formation by inhibiting autophagy in advanced atherosclerosis , 2020, Autophagy.
[25] Ye Gao,et al. Araloside C attenuates atherosclerosis by modulating macrophage polarization via Sirt1-mediated autophagy , 2020, Aging.
[26] Chaodong Wu,et al. Ginsenoside Rb1 alleviates ox-LDL-induced vascular endothelium senescence via the SIRT1/Beclin-1/autophagy axis. , 2020, Journal of cardiovascular pharmacology.
[27] Yu-yu Yao,et al. Insulin secretion impairment induced by rosuvastatin partly though autophagy in INS‐1E cells , 2020 .
[28] Xiaodong Li,et al. Artemisinin attenuated atherosclerosis in high-fat diet-fed ApoE-/- mice by promoting macrophage autophagy via AMPK/mTOR/ULK1 pathway. , 2019, Journal of cardiovascular pharmacology.
[29] Sanli Xing,et al. Quercetin Suppresses the Progression of Atherosclerosis by Regulating MST1-Mediated Autophagy in ox-LDL-Induced RAW264.7 Macrophage Foam Cells , 2019, International journal of molecular sciences.
[30] Dexin Yin,et al. Curcumin ameliorates atherosclerosis through upregulation of miR‐126 , 2019, Journal of cellular physiology.
[31] Yinglong Hou,et al. Dihydroartemisinin Induces Endothelial Cell Autophagy through Suppression of the Akt/mTOR Pathway , 2019, Journal of Cancer.
[32] A. Atanasov,et al. Targeting Foam Cell Formation in Atherosclerosis: Therapeutic Potential of Natural Products , 2019, Pharmacological Reviews.
[33] S. Jamuna,et al. Oligomeric proanthocyanidins and epigallocatechin gallate aggravate autophagy of foam cells through the activation of Class III PI3K/Beclin1-complex mediated cholesterol efflux. , 2019, BioFactors.
[34] Sanli Xing,et al. Quercetin has a protective effect on atherosclerosis via enhancement of autophagy in ApoE−/− mice , 2019, Experimental and therapeutic medicine.
[35] Jin Liu,et al. Paeonol induces cytoprotective autophagy via blocking the Akt/mTOR pathway in ovarian cancer cells , 2019, Cell Death & Disease.
[36] Yan Sun,et al. p62/mTOR/LXRα pathway inhibits cholesterol efflux mediated by ABCA1 and ABCG1 during autophagy blockage. , 2019, Biochemical and biophysical research communications.
[37] S. Sarkar,et al. Chemical Screening Approaches Enabling Drug Discovery of Autophagy Modulators for Biomedical Applications in Human Diseases , 2019, Front. Cell Dev. Biol..
[38] Yue Liu,et al. Ginkgo Biloba Leaf Extract Attenuates Atherosclerosis in Streptozotocin-Induced Diabetic ApoE-/- Mice by Inhibiting Endoplasmic Reticulum Stress via Restoration of Autophagy through the mTOR Signaling Pathway , 2019, Oxidative medicine and cellular longevity.
[39] Shengnan Guo,et al. Tanshinone IIA harmonizes the crosstalk of autophagy and polarization in macrophages via miR‐375/KLF4 pathway to attenuate atherosclerosis , 2019, International immunopharmacology.
[40] Qidi Ai,et al. SIRT1/AMPK and Akt/eNOS signaling pathways are involved in endothelial protection of total aralosides of Aralia elata (Miq) Seem against high‐fat diet‐induced atherosclerosis in ApoE−/− mice , 2019, Phytotherapy research : PTR.
[41] W. Martinet,et al. Altered mitochondrial quality control in Atg7-deficient VSMCs promotes enhanced apoptosis and is linked to unstable atherosclerotic plaque phenotype , 2019, Cell Death & Disease.
[42] H. Neels,et al. Everolimus depletes plaque macrophages, abolishes intraplaque neovascularization and improves survival in mice with advanced atherosclerosis. , 2019, Vascular pharmacology.
[43] Yufeng Ding,et al. Effects of puerarin on the pharmacokinetics of triptolide in rats , 2019, Pharmaceutical biology.
[44] Baomei Xia,et al. Anti-Depressive Effectiveness of Baicalin In Vitro and In Vivo , 2019, Molecules.
[45] Xi-Long Zheng,et al. Cholesterol transport system: An integrated cholesterol transport model involved in atherosclerosis. , 2019, Progress in lipid research.
[46] Guibo Sun,et al. Inhibitory Effects of Ginsenoside Rb1 on Early Atherosclerosis in ApoE-/- Mice via Inhibition of Apoptosis and Enhancing Autophagy , 2018, Molecules.
[47] G. Zhu,et al. Luteolin Induces Apoptosis and Autophagy in Mouse Macrophage ANA-1 Cells via the Bcl-2 Pathway , 2018, Journal of immunology research.
[48] Sanli Xing,et al. Quercetin protects against ox-LDL-induced injury via regulation of ABCAl, LXR-α and PCSK9 in RAW264.7 macrophages , 2018, Molecular medicine reports.
[49] Ying Tang,et al. Celosins inhibit atherosclerosis in ApoE-/- mice and promote autophagy flow. , 2018, Journal of ethnopharmacology.
[50] M. Bennett,et al. Vascular smooth muscle cell death, autophagy and senescence in atherosclerosis , 2018, Cardiovascular research.
[51] Li Yang,et al. Paeonol Inhibits Oxidized Low-Density Lipoprotein-Induced Vascular Endothelial Cells Autophagy by Upregulating the Expression of miRNA-30a , 2018, Front. Pharmacol..
[52] Xuesong Yang,et al. Baicalin administration attenuates hyperglycemia-induced malformation of cardiovascular system , 2018, Cell Death & Disease.
[53] M. Dai,et al. The Anti-atherosclerotic Effect of Paeonol against Vascular Smooth Muscle Cell Proliferation by Up-regulation of Autophagy via the AMPK/mTOR Signaling Pathway , 2018, Front. Pharmacol..
[54] A. Barakat,et al. Endothelial autophagic flux hampers atherosclerotic lesion development , 2017, Autophagy.
[55] Feng-Jie Tang,et al. MicroRNA-126 alleviates endothelial cells injury in atherosclerosis by restoring autophagic flux via inhibiting of PI3K/Akt/mTOR pathway. , 2018, Biochemical and biophysical research communications.
[56] Hua-fei Deng,et al. Puerarin inhibits expression of tissue factor induced by oxidative low‐density lipoprotein through activating the PI3K/Akt/eNOS pathway and inhibiting activation of ERK1/2 and NF‐&kgr;B , 2017, Life sciences.
[57] Qingwen Zhang,et al. Antimycobacterial and Anti-inflammatory Mechanisms of Baicalin via Induced Autophagy in Macrophages Infected with Mycobacterium tuberculosis , 2017, Front. Microbiol..
[58] Yuan Zhang,et al. Kaempferol alleviates ox-LDL-induced apoptosis by up-regulation of autophagy via inhibiting PI3K/Akt/mTOR pathway in human endothelial cells. , 2017, Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology.
[59] B. Ni,et al. Celastrol alleviates angiotensin II‑mediated vascular smooth muscle cell senescence via induction of autophagy. , 2017, Molecular medicine reports.
[60] Huixia Lu,et al. Ginsenoside Rb1 Enhances Atherosclerotic Plaque Stability by Improving Autophagy and Lipid Metabolism in Macrophage Foam Cells , 2017, Front. Pharmacol..
[61] A. Barakat,et al. Autophagy is required for endothelial cell alignment and atheroprotection under physiological blood flow , 2017, Proceedings of the National Academy of Sciences.
[62] Shibin Ding,et al. Green tea polyphenol treatment attenuates atherosclerosis in high-fat diet-fed apolipoprotein E-knockout mice via alleviating dyslipidemia and up-regulating autophagy , 2017, PloS one.
[63] K. Lesch,et al. T-cadherin promotes autophagy and survival in vascular smooth muscle cells through MEK1/2/Erk1/2 axis activation. , 2017, Cellular signalling.
[64] F. Cao,et al. Moderate Autophagy Inhibits Vascular Smooth Muscle Cell Senescence to Stabilize Progressed Atherosclerotic Plaque via the mTORC1/ULK1/ATG13 Signal Pathway , 2017, Oxidative medicine and cellular longevity.
[65] Qiang Xu,et al. Berberine inhibits palmitate-induced NLRP3 inflammasome activation by triggering autophagy in macrophages: A new mechanism linking berberine to insulin resistance improvement. , 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
[66] Shih-Ming Huang,et al. Epigallocatechin-3-gallate Reduces Scavenger Receptor A Expression and Foam Cell Formation in Human Macrophages. , 2017, Journal of agricultural and food chemistry.
[67] M. Fornage,et al. Heart Disease and Stroke Statistics—2017 Update: A Report From the American Heart Association , 2017, Circulation.
[68] J. Jukema,et al. Pathophysiology and treatment of atherosclerosis , 2017, Netherlands Heart Journal.
[69] Y. Li,et al. Berberine-sonodynamic therapy induces autophagy and lipid unloading in macrophage , 2017, Cell Death & Disease.
[70] Jincai Lu,et al. Chemical and bioactive comparison of flowers of Panax ginseng Meyer, Panax quinquefolius L., and Panax notoginseng Burk. , 2016, Journal of ginseng research.
[71] De-feng Pan,et al. Luteolin Attenuates Foam Cell Formation and Apoptosis in Ox-LDL-Stimulated Macrophages by Enhancing Autophagy , 2016, Cellular Physiology and Biochemistry.
[72] P. Liu,et al. Anti-atherosclerotic potential of baicalin mediated by promoting cholesterol efflux from macrophages via the PPARγ-LXRα-ABCA1/ABCG1 pathway. , 2016, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
[73] Yaping Zhang,et al. Endothelium-dependent and-independent relaxation induced by resveratrol in rat superior mesenteric arteries. , 2016, Experimental and therapeutic medicine.
[74] A. Pandolfi,et al. Physiology and pathophysiology of oxLDL uptake by vascular wall cells in atherosclerosis. , 2016, Vascular pharmacology.
[75] Chunbo Wang,et al. SIRT1/Atg5/autophagy are involved in the antiatherosclerosis effects of ursolic acid , 2016, Molecular and Cellular Biochemistry.
[76] G. D. De Meyer,et al. Spermidine reduces lipid accumulation and necrotic core formation in atherosclerotic plaques via induction of autophagy. , 2016, Atherosclerosis.
[77] Yongchun Cui,et al. Autophagy is associated with cell fate in the process of macrophage-derived foam cells formation and progress , 2016, Journal of Biomedical Science.
[78] Feifei Xuan,et al. Epigallocatechin gallate exerts protective effects against myocardial ischemia/reperfusion injury through the PI3K/Akt pathway-mediated inhibition of apoptosis and the restoration of the autophagic flux. , 2016, International journal of molecular medicine.
[79] Xi-Long Zheng,et al. Nicotinate-Curcumin Impedes Foam Cell Formation from THP-1 Cells through Restoring Autophagy Flux , 2016, PloS one.
[80] B. Razani,et al. Ursolic acid enhances macrophage autophagy and attenuates atherogenesis[S] , 2016, Journal of Lipid Research.
[81] Maoquan Li,et al. Quercitrin treatment protects endothelial progenitor cells from oxidative damage via inducing autophagy through extracellular signal-regulated kinase , 2016, Angiogenesis.
[82] Wawa Zhu,et al. Resveratrol Enhances Autophagic Flux and Promotes Ox-LDL Degradation in HUVECs via Upregulation of SIRT1 , 2016, Oxidative medicine and cellular longevity.
[83] Yong-jun Cao,et al. Rapamycin Inhibits Oxidized Low Density Lipoprotein Uptake in Human Umbilical Vein Endothelial Cells via mTOR/NF-κB/LOX-1 Pathway , 2016, PloS one.
[84] L. Ye,et al. Induction of autophagy by salidroside through the AMPK-mTOR pathway protects vascular endothelial cells from oxidative stress-induced apoptosis , 2016, Molecular and Cellular Biochemistry.
[85] Lifang Hu,et al. Rapamycin Promotes the Autophagic Degradation of Oxidized Low-Density Lipoprotein in Human Umbilical Vein Endothelial Cells , 2015, Journal of Vascular Research.
[86] He-da Zhang,et al. Luteolin Inhibits Breast Cancer Development and Progression In Vitro and In Vivo by Suppressing Notch Signaling and Regulating MiRNAs , 2015, Cellular Physiology and Biochemistry.
[87] Fumiaki Sato,et al. 7‐Ketocholesterol‐induced lysosomal dysfunction exacerbates vascular smooth muscle cell calcification via oxidative stress , 2015, Genes to cells : devoted to molecular & cellular mechanisms.
[88] M. Grootaert,et al. Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis , 2015, Autophagy.
[89] E. Kang,et al. Chronic HMGCR/HMG-CoA reductase inhibitor treatment contributes to dysglycemia by upregulating hepatic gluconeogenesis through autophagy induction , 2015, Autophagy.
[90] Chunguang Qiu,et al. Quercetin increases macrophage cholesterol efflux to inhibit foam cell formation through activating PPARγ-ABCA1 pathway. , 2015, International journal of clinical and experimental pathology.
[91] K. Kawabata,et al. Quercetin and related polyphenols: new insights and implications for their bioactivity and bioavailability. , 2015, Food & function.
[92] C. Vindis. Autophagy: an emerging therapeutic target in vascular diseases , 2015, British journal of pharmacology.
[93] A. Orekhov,et al. Vascular smooth muscle cell in atherosclerosis , 2015, Acta physiologica.
[94] Ira Tabas,et al. Recent insights into the cellular biology of atherosclerosis , 2015, The Journal of cell biology.
[95] Jun Wang,et al. Berberine alleviates ox-LDL induced inflammatory factors by up-regulation of autophagy via AMPK/mTOR signaling pathway , 2015, Journal of Translational Medicine.
[96] Hui-Hsuan Lin. In Vitro and in Vivo Atheroprotective Effects of Gossypetin against Endothelial Cell Injury by Induction of Autophagy. , 2015, Chemical research in toxicology.
[97] B. Friguet,et al. Anti-Inflammatory and Antiatherogenic Effects of the NLRP3 Inflammasome Inhibitor Arglabin in ApoE2.Ki Mice Fed a High-Fat Diet , 2015, Circulation.
[98] K. Vandenbroeck,et al. Autophagic Marker MAP1LC3B Expression Levels Are Associated with Carotid Atherosclerosis Symptomatology , 2014, PloS one.
[99] M. Mi,et al. Delphinidin-3-glucoside protects human umbilical vein endothelial cells against oxidized low-density lipoprotein-induced injury by autophagy upregulation via the AMPK/SIRT1 signaling pathway. , 2014, Molecular nutrition & food research.
[100] T. Graham,et al. Impairment of autophagy in endothelial cells prevents shear-stress-induced increases in nitric oxide bioavailability. , 2014, Canadian journal of physiology and pharmacology.
[101] Ping Li,et al. mTOR enhances foam cell formation by suppressing the autophagy pathway. , 2014, DNA and cell biology.
[102] J. Pang,et al. The anti-atherosclerotic effect of tanshinone IIA is associated with the inhibition of TNF-α-induced VCAM-1, ICAM-1 and CX3CL1 expression. , 2014, Phytomedicine : international journal of phytotherapy and phytopharmacology.
[103] P. Little,et al. Tanshinone IIA suppresses cholesterol accumulation in human macrophages: role of heme oxygenase-1[S] , 2014, Journal of Lipid Research.
[104] Yawei Xu,et al. Enhancement in efferocytosis of oxidized low-density lipoprotein-induced apoptotic RAW264.7 cells through Sirt1-mediated autophagy , 2013, International journal of molecular medicine.
[105] B. Hill,et al. Implications of autophagy for vascular smooth muscle cell function and plasticity. , 2013, Free radical biology & medicine.
[106] Xiaoping Zhou,et al. Resveratrol attenuates vascular endothelial inflammation by inducing autophagy through the cAMP signaling pathway , 2013, Autophagy.
[107] I. Perrotta. The use of electron microscopy for the detection of autophagy in human atherosclerosis. , 2013, Micron.
[108] P. Hopkins,et al. Molecular biology of atherosclerosis. , 2013, Physiological reviews.
[109] N. Pallet,et al. Adverse events associated with mTOR inhibitors , 2013, Expert opinion on drug safety.
[110] J. Chen,et al. Resveratrol Attenuates Oxidative Stress Induced by Balloon Injury in the Rat Carotid Artery Through Actions on the ERK1/2 and NF-Kappa B Pathway , 2013, Cellular Physiology and Biochemistry.
[111] In vitro interaction of artemisinin derivatives or the fully synthetic peroxidic anti-malarial OZ277 with thapsigargin in Plasmodium falciparum strains , 2013, Malaria Journal.
[112] S. Shyue,et al. Molecular mechanism of curcumin on the suppression of cholesterol accumulation in macrophage foam cells and atherosclerosis. , 2012, Molecular nutrition & food research.
[113] M. Kastan,et al. Autophagy links inflammasomes to atherosclerotic progression. , 2012, Cell metabolism.
[114] Jennifer Martinez,et al. Macrophage autophagy plays a protective role in advanced atherosclerosis. , 2012, Cell metabolism.
[115] A. Landar,et al. Hemin causes mitochondrial dysfunction in endothelial cells through promoting lipid peroxidation: the protective role of autophagy. , 2012, American journal of physiology. Heart and circulatory physiology.
[116] Shilin Chen,et al. Genome-wide identification and characterization of novel genes involved in terpenoid biosynthesis in Salvia miltiorrhiza , 2022 .
[117] D. Schrijvers,et al. Autophagy in Atherosclerosis: A Potential Drug Target for Plaque Stabilization , 2011, Arteriosclerosis, thrombosis, and vascular biology.
[118] Ira Tabas,et al. Autophagy regulates cholesterol efflux from macrophage foam cells via lysosomal acid lipase. , 2011, Cell metabolism.
[119] M. Czaja,et al. Autophagy regulates lipid metabolism , 2009, Nature.
[120] M. López-Lázaro. Distribution and biological activities of the flavonoid luteolin. , 2009, Mini reviews in medicinal chemistry.
[121] D. Liao,et al. Curcumin inhibits cellular cholesterol accumulation by regulating SREBP-1/caveolin-1 signaling pathway in vascular smooth muscle cells , 2008, Acta Pharmacologica Sinica.
[122] Zhi-Hong Jiang,et al. Quantification of two polyacetylenes in Radix Ginseng and roots of related Panax species using a gas chromatography-mass spectrometric method. , 2007, Journal of agricultural and food chemistry.
[123] M. Ali,et al. Ursolic acid: a potent Inhibitor of superoxides produced in the cellular system , 2007, Phytotherapy research : PTR.
[124] G. D. De Meyer,et al. Selective depletion of macrophages in atherosclerotic plaques via macrophage-specific initiation of cell death. , 2007, Trends in cardiovascular medicine.
[125] G. D. De Meyer,et al. Everolimus-Induced mTOR Inhibition Selectively Depletes Macrophages in Atherosclerotic Plaques by Autophagy , 2007, Autophagy.
[126] D. Agrawal,et al. Autophagy of Vascular Smooth Muscle Cells in Atherosclerotic Lesions , 2007, Autophagy.
[127] Junying Yuan,et al. Autophagy in cell death: an innocent convict? , 2005, The Journal of clinical investigation.
[128] F. Shode,et al. Cardiovascular, antihyperlipidemic and antioxidant effects of oleanolic and ursolic acids in experimental hypertension. , 2003, Phytomedicine : international journal of phytotherapy and phytopharmacology.
[129] Christopher K. Glass,et al. Atherosclerosis The Road Ahead , 2001, Cell.