Epileptic patients’ willingness to receive cell-phone based medication reminder in Northwest Ethiopia

Poor adherence compromises medication treatment effectiveness which results in suboptimal illness control. This can lead to increased use of healthcare services, reduction in patients’ quality of life and increased healthcare costs. Reminding patients of their medication intake increases their adherence. Therefore, this study aimed to assess the willingness of epileptic patients to receive cell-phone based medication reminders and its associated factors in Northwest Ethiopia. Institution based cross sectional study was conducted in the study period scheduled from March 1 to April 30, 2018 to interview 422 study participants at University of Gondar Comprehensive and Specialized Hospital, Northwest Ethiopia. Systematic random sampling was used to select 422 epileptic patients. A structured interviewer administered questionnaire was used to collect data and analyzed by using SPSS version 21. Binary and multivariate logistic regression analysis was performed to identify the determinant factors for willingness to receive cell-phone based medication reminders. P < 0.05 at 95% confidence interval was considered statistically significant. A total of 394 (93% response rate) respondents were interviewed. The majority of respondents 262 (66.5%) owned a cellphone. Among the participants 271 (68.8%) were willing to receive reminder messages. In the multivariate regression analysis; living in urban areas (AOR = 5.63, 95% CI; 3.18–9.96), experience of forgetting things (AOR = 2.63, 95% CI; 1.44–4.80), forgetting to take Long-term Antiepileptic Drugs (AEDs) (AOR = 2.17, 95% CI; 1.06–4.43) and average monthly income ≥2000 birr (AOR = 2.43, 95% CI; 1.03–5.75) were significantly associated with willingness to receive cell-phone medication reminders. Pertaining to marital status; being married (AOR = 5.75, 95% CI; 1.11–29.70) or divorced (AOR = 5.15, 95% CI; 1.29–20.49) participants were also more willing to receive cell-phone medication reminders as compared to singles. Most respondents have a cellphone and were willing to use it as a medication reminder. Marital status, place of residence, average monthly income, experience of forgetting things since they started AED, forget to take AED are the most notable factors that are associated with the willingness of patients to receive cell phone drug reminder messages.

[1]  Fleur Fritz,et al.  Willingness to receive text message medication reminders among patients on antiretroviral treatment in North West Ethiopia: A cross-sectional study , 2015, BMC Medical Informatics and Decision Making.

[2]  Y. Yazdanpanah,et al.  Tolerability of two different combinations of antiretroviral drugs including tenofovir used in occupational and nonoccupational postexposure prophylaxis for HIV. , 2010, AIDS patient care and STDs.

[3]  Donald L. Schomer,et al.  Project EASE: a study to test a psychosocial model of epilepsy medication management , 2004, Epilepsy & Behavior.

[4]  P. Schraeder,et al.  Forensic antiepileptic drug levels in autopsy cases of epilepsy , 2011, Epilepsy & Behavior.

[5]  Luís Carlos de Souza Ferreira,et al.  Bacillus subtilis Spores as Vaccine Adjuvants: Further Insights into the Mechanisms of Action , 2014, PloS one.

[6]  Quentin Eichbaum,et al.  Exploring the patterns of use and the feasibility of using cellular phones for clinic appointment reminders and adherence messages in an antiretroviral treatment clinic, Durban, South Africa. , 2010, AIDS patient care and STDs.

[7]  E. Kravariti,et al.  Mobile phone text message reminders of antipsychotic medication: is it time and who should receive them? A cross-sectional trust-wide survey of psychiatric inpatients , 2014, BMC Psychiatry.

[8]  Josemir W Sander,et al.  Prevalence and Pattern of Epilepsy Treatment in Different Socioeconomic Classes in Brazil , 2007, Epilepsia.

[9]  K. Meador,et al.  Cognitive side effects of antiepileptic drugs , 2004, Epilepsy & Behavior.

[10]  Hilde van der Togt,et al.  Publisher's Note , 2003, J. Netw. Comput. Appl..

[11]  R Kale,et al.  Bringing epilepsy out of the shadows , 1997, BMJ.

[12]  Dieter Schmidt,et al.  Modern management of epilepsy: A practical approach , 2008, Epilepsy & Behavior.

[13]  Katrina J Serrano,et al.  Willingness to Exchange Health Information via Mobile Devices: Findings From a Population-Based Survey , 2016, The Annals of Family Medicine.

[14]  Sherwin I. DeSouza,et al.  Mobile Phones: The Next Step towards Healthcare Delivery in Rural India? , 2014, PloS one.

[15]  R. Verbrugge,et al.  Impact of Medication Adherence on Hospitalization Risk and Healthcare Cost , 2005, Medical care.

[16]  Abigail L. Wroe,et al.  Intentional and Unintentional Nonadherence: A Study of Decision Making , 2002, Journal of Behavioral Medicine.

[18]  Anuja Roy,et al.  Medication compliance and persistence: terminology and definitions. , 2008, Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research.

[19]  S. Candrilli,et al.  Prevalence and cost of nonadherence with antiepileptic drugs in an adult managed care population , 2008, Epilepsia.

[20]  M Christopher Roebuck,et al.  Medication adherence leads to lower health care use and costs despite increased drug spending. , 2011, Health affairs.

[21]  J. Wheless,et al.  Association of non-adherence to antiepileptic drugs and seizures, quality of life, and productivity: Survey of patients with epilepsy and physicians , 2008, Epilepsy & Behavior.

[22]  Ross T Tsuyuki,et al.  A meta-analysis of the association between adherence to drug therapy and mortality , 2006, BMJ : British Medical Journal.

[23]  R. Letz,et al.  The complexity of treatments for persons with epilepsy , 2005, Epilepsy & Behavior.