Differences in the angiogenesis of benign and malignant ovarian tumors, demonstrated by analyses of color doppler ultrasound, immunohistochemistry, and microvessel density

To clarify the differences in angiogenesis between benign and malignant ovarian tumors, the authors examined the immunohistochemical characteristics and the density of tumor vessels in both tumor groups. Intratumoral vascularization was observed preoperatively by transvaginal color Doppler ultrasound.

[1]  D. Pickens,et al.  Quantification of tumor vascularity and flow with amplitude color Doppler sonography in an experimental model: preliminary results. , 1996, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

[2]  A. Tekay,et al.  Controversies in Assessment of Ovarian Tumors with Transvaginal Color Doppler Ultrasound , 1996, Acta obstetricia et gynecologica Scandinavica.

[3]  Y. Chung,et al.  Tumour angiogenesis and tumour cell proliferation as prognostic indicators in gastric carcinoma. , 1995, British Journal of Cancer.

[4]  R. Bahado-Singh,et al.  Effects of external radiotherapy on uterine blood flow in patients with advanced cervical carcinoma assessed by Color Doppler ultrasonography , 1995, Cancer.

[5]  S. Steinberg,et al.  Tumor angiogenesis in advanced stage ovarian carcinoma. , 1995, The American journal of pathology.

[6]  P. V. van Diest,et al.  Prognostic value of microvessel quantitation in cisplatin treated FIGO 3 and 4 ovarian cancer patients. , 1995, Pathology, research and practice.

[7]  F. Hsieh,et al.  Vascular patterns of gestational trophoblastic tumors by color doppler ultrasound , 1994, Cancer.

[8]  S. Abe,et al.  Tumor angiogenesis in human lung adenocarcinoma , 1994, Cancer.

[9]  T. Bourne,et al.  Association of ovarian malignancy with expression of platelet-derived endothelial cell growth factor. , 1994, Journal of the National Cancer Institute.

[10]  N. Weidner,et al.  Correlation of intratumoral endothelial cell proliferation with microvessel density (tumor angiogenesis) and tumor cell proliferation in breast carcinoma. , 1994, The American journal of pathology.

[11]  A. Kurjak,et al.  An attempt to screen asymptomatic women for ovarian and endometrial cancer with transvaginal color and pulsed Doppler sonography. , 1994, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

[12]  L. Valentin,et al.  Limited Contribution of Doppler Velocimetry to the Differential Diagnosis of Extrauterine Pelvic Tumors , 1994, Obstetrics and gynecology.

[13]  N. Weidner,et al.  Tumor microvessel density, p53 expression, tumor size, and peritumoral lymphatic vessel invasion are relevant prognostic markers in node-negative breast carcinoma. , 1994, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[14]  N. Weidner,et al.  Tumor angiogenesis: review of current applications in tumor prognostication. , 1993, Seminars in diagnostic pathology.

[15]  J B Davey,et al.  Breast diseases: color Doppler US in differential diagnosis. , 1993, Radiology.

[16]  E. McDermott,et al.  Color Doppler sonography in the evaluation of palpable breast masses. , 1993, AJR. American journal of roentgenology.

[17]  W Blumenfeld,et al.  Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma. , 1993, The American journal of pathology.

[18]  A. Fleischer,et al.  Color Doppler Sonography of Ovarian Masses: A Multiparameter Analysis , 1993, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

[19]  F Pozza,et al.  Tumor angiogenesis: a new significant and independent prognostic indicator in early-stage breast carcinoma. , 1992, Journal of the National Cancer Institute.

[20]  A. Kurjak,et al.  New scoring system for prediction of ovarian malignancy based on transvaginal color Doppler sonography , 1992 .

[21]  A. Harris,et al.  Angiogenesis, assessed by platelet/endothelial cell adhesion molecule antibodies, as indicator of node metastases and survival in breast cancer , 1992, The Lancet.

[22]  A. Tekay,et al.  Validity of Pulsatility and Resistance Indices in Classification of Adnexal Tumors with Transvaginal Color Doppler Ultrasound , 1992, Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology.

[23]  C. Angeletti,et al.  Relation of neovascularisation to metastasis of non-small-cell lung cancer , 1992, The Lancet.

[24]  A. Lee,et al.  Microvessel quantitation and prognosis in invasive breast carcinoma. , 1992, Human pathology.

[25]  P. Burns.  Measuring volume flow with Doppler ultrasound—an old nut , 1992, Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology.

[26]  R Bicknell,et al.  Heterogeneity of vascular endothelial cells with relevance to diagnosis of vascular tumours. , 1992, Journal of clinical pathology.

[27]  A. Fleischer,et al.  Assessment of ovarian tumor vascularity with transvaginal color Doppler sonography. , 1991, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

[28]  A. Kurjak,et al.  Evaluation of adnexal masses with transvaginal color ultrasound. , 1991, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

[29]  A. Harris,et al.  Novel growth regulatory factors and tumour angiogenesis. , 1991, European journal of cancer.

[30]  K. Taylor,et al.  Renal masses: characterization with Doppler US. , 1990, Radiology.

[31]  D. Mason,et al.  JC70: a new monoclonal antibody that detects vascular endothelium associated antigen on routinely processed tissue sections. , 1990, Journal of clinical pathology.

[32]  M. Greaves,et al.  Leukocyte antigen CD34 is expressed by a subset of cultured endothelial cells and on endothelial abluminal microprocesses in the tumor stroma. , 1990, Laboratory investigation; a journal of technical methods and pathology.

[33]  Tohru Takahashi,et al.  Encasement and other deformations of tumor‐embedded host arteries due to loss of medial smooth muscles. Morphometric and three‐dimensional reconstruction studies on some human carcinomas , 1990, Cancer.

[34]  J. Folkman.  What is the evidence that tumors are angiogenesis dependent? , 1990, Journal of the National Cancer Institute.

[35]  T. Bourne,et al.  Transvaginal colour flow imaging: a possible new screening technique for ovarian cancer. , 1989, BMJ.

[36]  J. Elias,et al.  Sensitivity and detection efficiency of the peroxidase antiperoxidase (PAP), avidin-biotin peroxidase complex (ABC), and peroxidase-labeled avidin-biotin (LAB) methods. , 1989, American journal of clinical pathology.

[37]  D. Hanahan,et al.  Induction of angiogenesis during the transition from hyperplasia to neoplasia , 1989, Nature.

[38]  B. Trudinger,et al.  Doppler ultrasound waveform indices: A/B ratio, pulsatility index and Pourcelot ratio , 1988, British journal of obstetrics and gynaecology.

[39]  K. Kozlowski.  Ovarian masses. , 1999, Adolescent medicine.

[40]  E. van Marck,et al.  Microvessel density, endothelial cell proliferation and tumour cell proliferation in human colorectal adenocarcinomas. , 1995, Annals of oncology : official journal of the European Society for Medical Oncology.

[41]  D. Carter,et al.  Correlation of Doppler US tumor signals with neovascular morphologic features. , 1988, Radiology.

[42]  J. Folkman,et al.  Angiogenic factors. , 1987, Science.