Atherosclerosis of the ascending aorta is an independent predictor of long-term neurologic events and mortality.

[1]  C. M. Flory,et al.  Arterial Occlusions Produced by Emboli from Eroded Aortic Atheromatous Plaques. , 1945, The American journal of pathology.

[2]  C. Duyckaerts,et al.  The prevalence of ulcerated plaques in the aortic arch in patients with stroke. , 1992, The New England journal of medicine.

[3]  L D Fisher,et al.  Clinical and Angiographic Predictors of Operative Mortality from the Collaborative Study in Coronary Artery Surgery (CASS) , 1981, Circulation.

[4]  M. Smith,et al.  The clinical spectrum of renal cholesterol embolization. , 1981, The American journal of medicine.

[5]  G. Plotnick,et al.  Intraaortic debris as a potential source of embolic stroke. , 1992, The American journal of cardiology.

[6]  P. Greenland,et al.  Echocardiography in Diagnostic Assessment of Stroke , 1981 .

[7]  S. Adler,et al.  Control of cholesterol embolization by discontinuation of anticoagulant therapy. , 1978, The American journal of the medical sciences.

[8]  Ruth Bonita,et al.  Epidemiology of stroke , 1992, The Lancet.

[9]  G. Sutherland,et al.  Transesophageal echocardiography in the detection of intracardiac embolic sources in patients with transient ischemic attacks. , 1990, Stroke.

[10]  D. Miller,et al.  Mural thrombi in myocardial infarctions. Prospective evaluation by two-dimensional echocardiography. , 1983, The American journal of medicine.

[11]  M. Hennerici,et al.  Carotid artery disease assessed by color Doppler flow imaging: correlation with standard Doppler sonography and angiography. , 1990, AJR. American journal of roentgenology.

[12]  V. Fuster,et al.  Thrombosis and embolism from cardiac chambers and infected valves. , 1986, Journal of the American College of Cardiology.

[13]  P. Wolf,et al.  Epidemiologic assessment of chronic atrial fibrillation and risk of stroke , 1978, Neurology.

[14]  Daniel B Hier,et al.  Infarcts of undetermined cause: The NINCDS stroke data bank , 1989, Annals of neurology.

[15]  Winter Wj Atheromatous emboli; a cause of cerebral infarction; report of two cases. , 1957 .

[16]  D. Levy,et al.  Mitral annular calcification and the risk of stroke in an elderly cohort. , 1992, The New England journal of medicine.

[17]  D. Reich,et al.  The Ascending Aorta: How Much Does Transesophageal Echocardiography See? , 1994, Anesthesia and analgesia.

[18]  C. Doherty,et al.  Vascular events during follow-up in patients with aortic arch atherosclerosis. , 1997, Stroke.

[19]  I. Kronzon,et al.  Protruding atheromas in the thoracic aorta and systemic embolization. , 1991, Annals of internal medicine.

[20]  A. Rodgers,et al.  Blood pressure, antihypertensive treatment and stroke risk. , 1994, Journal of hypertension. Supplement : official journal of the International Society of Hypertension.

[21]  J. Gold,et al.  Severity of Aortic Atheromatous Disease Diagnosed by Transesophageal Echocardiography Predicts Stroke and Other Outcomes Associated with Coronary Artery Surgery: A Prospective Study , 1996, Anesthesia and analgesia.

[22]  D L McGee,et al.  Duration of atrial fibrillation and imminence of stroke: the Framingham study. , 1983, Stroke.

[23]  H. Barnett,et al.  Cerebral ischemic events associated with prolapsing mitral valve. , 1976, Archives of neurology.

[24]  W. Daniel,et al.  Left atrial spontaneous echo contrast in mitral valve disease: an indicator for an increased thromboembolic risk. , 1988, Journal of the American College of Cardiology.

[25]  N. Kouchoukos,et al.  Intraoperative transesophageal echocardiography and epiaortic ultrasound for assessment of atherosclerosis of the thoracic aorta. , 1996, Journal of the American College of Cardiology.

[26]  N. Lassen Epidemiologic assessment of the role of blood pressure in stroke. , 1996, JAMA.

[27]  N. Kouchoukos,et al.  Management of the severely atherosclerotic ascending aorta during cardiac operations. A strategy for detection and treatment. , 1992, The Journal of thoracic and cardiovascular surgery.

[28]  A. Davies,et al.  Endarterectomy for asymptomatic carotid artery stenosis , 1995, BMJ.

[29]  R. Collins,et al.  Blood pressure, stroke, and coronary heart disease Part 2, short-term reductions in blood pressure: overview of randomised drug trials in their epidemiological context , 1990, The Lancet.

[30]  C. Helmers,et al.  The natural history of stroke in diabetic patients. , 2009, Acta medica Scandinavica.

[31]  J. Ross,et al.  Recognition and embolic potential of intraaortic atherosclerotic debris. , 1991, Journal of the American College of Cardiology.

[32]  M. Verani,et al.  Coronary artery disease in patients with cerebrovascular disease: A prospective study , 1984, Annals of neurology.

[33]  I. Gore,et al.  Spontaneous atheromatous embolization. Review of the literature and a report of 16 additional cases. , 1960, American journal of clinical pathology.

[34]  D. Sackett,et al.  Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. , 1991, The New England journal of medicine.

[35]  A. Labovitz,et al.  Mobile aortic atheroma and systemic emboli: efficacy of anticoagulation and influence of plaque morphology on recurrent stroke. , 1998, Journal of the American College of Cardiology.

[36]  F. Loop,et al.  Atheroembolism from the ascending aorta. An emerging problem in cardiac surgery. , 1992, The Journal of thoracic and cardiovascular surgery.

[37]  P. Wolf,et al.  Epidemiologic assessment of the role of blood pressure in stroke. The Framingham study. , 1970, JAMA.

[38]  T. Itoh,et al.  Intraoperative ultrasonic imaging of the ascending aorta in ischemic heart disease. , 1990, The Annals of thoracic surgery.

[39]  C. Helgason Blood glucose and stroke. , 1988, Stroke.

[40]  N. Kouchoukos,et al.  Atherosclerosis of the ascending aorta is a predictor of renal dysfunction after cardiac operations. , 1999, The Journal of thoracic and cardiovascular surgery.

[41]  M. Beal,et al.  Cholesterol embolism as a cause of transient ischemic attacks and cerebral infarction , 1981, Neurology.

[42]  R. Sacco,et al.  Atherosclerotic disease of the aortic arch as a risk factor for recurrent ischemic stroke. , 1996, The New England journal of medicine.

[43]  J. Kassirer,et al.  Atheromatous emboli with progressive renal failure. Renal arteriography as the probable inciting factor. , 1968, Annals of internal medicine.

[44]  J. Weinberger,et al.  Factors contributing to stroke in patients with atherosclerotic disease of the great vessels: the role of diabetes. , 1983, Stroke.

[45]  D. Skorton,et al.  Cardiac evaluation of the patient with stroke. , 1990, Stroke.

[46]  A. Buchan,et al.  *North American Symptomatic Carotid Endarterectomy Trial (NASCET) Steering Committee. Beneficial Effect of Carotid Endarterectomy in Symptomatic Patients with High-Grade Carotid Stenosis. , 1991 .

[47]  N. Kouchoukos,et al.  Strategy for the reduction of stroke incidence in cardiac surgical patients. , 1993, The Annals of thoracic surgery.

[48]  G. Sicard,et al.  Transesophageal echocardiography in the detection of cardiovascular sources of peripheral vascular embolism , 1995, Annals of vascular surgery.

[49]  Sturgill Bc,et al.  CEREBRAL INFARCTION BY ATHEROMATOUS EMBOLI. REPORT OF CASE AND REVIEW OF LITERATURE. , 1963 .

[50]  S. Teitelbaum,et al.  Atheromatous embolization; a factor in peripheral gangrene. , 1959, The New England journal of medicine.

[51]  R. Auerbach,et al.  "Purple toes": an uncommon sequela of oral coumarin drug therapy. , 1961, Annals of internal medicine.

[52]  N. Kouchoukos,et al.  Atherosclerosis of the Ascending Aorta: Prevalence and Role as an Independent Predictor of Cerebrovascular Events in Cardiac Patients , 1994, Stroke.

[53]  R. Sacco,et al.  Prophylactic Neuroprotection for Cerebral Ischemia , 1994, Stroke.

[54]  N. Kouchoukos,et al.  Preoperative carotid artery screening in elderly patients undergoing cardiac surgery. , 1992, Journal of vascular surgery.

[55]  I. Kronzon,et al.  High Risk for Vascular Events in Patients with Protruding Aortic Atheromas: A Prospective Study , 1994, Journal of the American College of Cardiology.

[56]  N. Kouchoukos,et al.  Intraoperative ultrasonographic evaluation of the ascending aorta in 100 consecutive patients undergoing cardiac surgery. , 1991, Circulation.

[57]  J. C. Merriam,et al.  Cholesterol Embolization: From Pathological Curiosity to Clinical Entity , 1967, Circulation.

[58]  P. Wolf,et al.  Manifestations of coronary disease predisposing to stroke. The Framingham study. , 1983, JAMA.

[59]  Y. Hosoda,et al.  Significance of atherosclerotic changes of the ascending aorta during coronary bypass surgery with intraoperative detection by echography. , 1991, The Journal of cardiovascular surgery.

[60]  J. Whisnant Epidemiology of stroke: emphasis on transient cerebral ischemia attacks and hypertension. , 1974, Stroke.