Burden of syphilis infections in Shenzhen, China: a preliminary estimation

Information on the prevalence and incidence of sexually transmitted infections is important for developing prevention and control strategies and allocating human and financial resources. However, there are no available estimates of such information for many areas in China. In this study, we used the existing data to make a preliminary estimation of syphilis infections in Shenzhen city, in south-eastern China. Data on prevalence rates of syphilis infections among different populations were obtained from the local HIV/sexually transmitted disease second-generation surveillance programme, and the sizes of different populations were estimated based on the most recently available figures. It was estimated that 83,760 (range 77,490–90,020) people are currently infected with syphilis, giving a prevalence of 0.71–0.82% (0.76% on average) in Shenzhen. Around 18% of these syphilis infections occur among men who have sex with men and another 15.8% and 8.7% occur among female sex workers and their clients, respectively. These estimates suggest that a combination of unprotected paid sex and sex between men may be sustaining the epidemic of syphilis in the study area. The preliminary estimates will assist the government in planning and improving its comprehensive intervention programmes for the future control and prevention of syphilis.

[1]  R. Peeling,et al.  Risk factors for syphilis infection among pregnant women: results of a case-control study in Shenzhen, China , 2007, Sexually Transmitted Infections.

[2]  Jinquan Cheng,et al.  Syphilis screening and intervention in 500 000 pregnant women in Shenzhen, the People’s Republic of China , 2007, Sexually Transmitted Infections.

[3]  Myron S. Cohen,et al.  Syphilis in China: results of a national surveillance programme , 2007, The Lancet.

[4]  Myron S. Cohen,et al.  China’s Syphilis Epidemic: A Systematic Review of Seroprevalence Studies , 2006, Sexually transmitted diseases.

[5]  X. Sun,et al.  Estimating the number of people at risk for and living with HIV in China in 2005: methods and results , 2006, Sexually Transmitted Infections.

[6]  R. Bollinger,et al.  High rates of syphilis among STI patients are contributing to the spread of HIV-1 in India , 2006, Sexually Transmitted Infections.

[7]  Z. Qian,et al.  Risk of HIV/AIDS in China: subpopulations of special importance , 2005, Sexually Transmitted Infections.

[8]  E. Laumann,et al.  Population-based study of chlamydial infection in China: a hidden epidemic. , 2003, JAMA.

[9]  G. Liang,et al.  Epidemiologic Trends of Sexually Transmitted Diseases in China , 2000, Sexually transmitted diseases.

[10]  D. Fleming,et al.  From epidemiological synergy to public health policy and practice: the contribution of other sexually transmitted diseases to sexual transmission of HIV infection. , 1999, Sexually transmitted infections.

[11]  Chen Qing-shan Analysis on the Epidemiololgy of Syphilis from 1984 to 2003 in Shenzhen , 2005 .

[12]  Chen Lin,et al.  Multiplier method to estimate the number of commercial sex workers and drug users in Shenzhen , 2004 .