Simvastatin and rosuvastatin mobilize Endothelial Progenitor Cells but do not prevent their acute decrease during systemic inflammation.

[1]  M. Wolzt,et al.  In-vivo effects of simvastatin and rosuvastatin on global gene expression in peripheral blood leucocytes in a human inflammation model , 2008, Pharmacogenetics and genomics.

[2]  J. Leitner,et al.  Effects of low dose endotoxemia on endothelial progenitor cells in humans. , 2007, Atherosclerosis.

[3]  J. Ablin,et al.  Effect of anti-TNFalpha treatment on circulating endothelial progenitor cells (EPCs) in rheumatoid arthritis. , 2006, Life sciences.

[4]  B. Jilma,et al.  Coagulation interventions in experimental human endotoxemia. , 2006, Translational research : the journal of laboratory and clinical medicine.

[5]  A. Quyyumi,et al.  Increased circulating endothelial progenitor cells are associated with survival in acute lung injury. , 2005, American journal of respiratory and critical care medicine.

[6]  H. Kubo,et al.  Increased circulating endothelial progenitor cells in patients with bacterial pneumonia: evidence that bone marrow derived cells contribute to lung repair , 2005, Thorax.

[7]  M. Wolzt,et al.  Simvastatin Blunts Endotoxin-Induced Tissue Factor In Vivo , 2005, Circulation.

[8]  J. Smolen,et al.  Depletion of Endothelial Progenitor Cells in the Peripheral Blood of Patients With Rheumatoid Arthritis , 2005, Circulation.

[9]  M. Wolzt,et al.  Simvastatin Prevents Vascular Hyporeactivity During Inflammation , 2004, Circulation.

[10]  M. Tendera,et al.  Mobilization of CD34/CXCR4+, CD34/CD117+, c-met+ Stem Cells, and Mononuclear Cells Expressing Early Cardiac, Muscle, and Endothelial Markers Into Peripheral Blood in Patients With Acute Myocardial Infarction , 2004, Circulation.

[11]  F. Emmrich,et al.  Increase of Circulating Endothelial Progenitor Cells in Patients with Coronary Artery Disease After Exercise-Induced Ischemia , 2004, Arteriosclerosis, thrombosis, and vascular biology.

[12]  B. Jilma,et al.  Recombinant human activated protein C (rhAPC; drotrecogin alfa [activated]) has minimal effect on markers of coagulation, fibrinolysis, and inflammation in acute human endotoxemia. , 2003, Blood.

[13]  M. Wolzt,et al.  Marked increase in vascular endothelial growth factor concentrations during Escherichia coli endotoxin‐induced acute inflammation in humans , 2003, European journal of clinical investigation.

[14]  A. Quyyumi,et al.  Circulating endothelial progenitor cells, vascular function, and cardiovascular risk. , 2003, The New England journal of medicine.

[15]  Shahin Rafii,et al.  Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration , 2003, Nature Medicine.

[16]  H. Eichler,et al.  Pharmacodynamics of active site‐inhibited factor VIIa in endotoxin‐induced coagulation in humans , 2002, Clinical pharmacology and therapeutics.

[17]  A. Suffredini,et al.  Human models of innate immunity: local and systemic inflammatory responses , 2001, Journal of endotoxin research.

[18]  J. Isner,et al.  HMG-CoA reductase inhibitor mobilizes bone marrow--derived endothelial progenitor cells. , 2001, The Journal of clinical investigation.

[19]  A M Zeiher,et al.  HMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI 3-kinase/Akt pathway. , 2001, The Journal of clinical investigation.

[20]  S. Fichtlscherer,et al.  Increase in Circulating Endothelial Progenitor Cells by Statin Therapy in Patients With Stable Coronary Artery Disease , 2001, Circulation.

[21]  T. Murohara,et al.  Mobilization of Endothelial Progenitor Cells in Patients With Acute Myocardial Infarction , 2001, Circulation.

[22]  J. Isner,et al.  VEGF gene transfer mobilizes endothelial progenitor cells in patients with inoperable coronary disease. , 2000, The Annals of thoracic surgery.

[23]  T. Awata,et al.  Lipophilic HMG-CoA reductase inhibitor has an anti-inflammatory effect: reduction of MRNA levels for interleukin-1beta, interleukin-6, cyclooxygenase-2, and p22phox by regulation of peroxisome proliferator-activated receptor alpha (PPARalpha) in primary endothelial cells. , 2000, Life sciences.

[24]  H. Eichler,et al.  Regulation of adhesion molecules during human endotoxemia. No acute effects of aspirin. , 1999, American journal of respiratory and critical care medicine.

[25]  Takayuki Asahara,et al.  Isolation of Putative Progenitor Endothelial Cells for Angiogenesis , 1997, Science.

[26]  T. Luther,et al.  Validation of a novel tissue factor assay in experimental human endotoxemia. , 2003, Thrombosis research.

[27]  M. Wolzt,et al.  Similar Effects of Atorvastatin, Simvastatin and Pravastatin on Thrombogenic and Inflammatory Parameters in Patients with Hypercholesterolemia , 2001, Thrombosis and Haemostasis.

[28]  N. Rifai,et al.  Current recommendations of the Adult Treatment Panel and the Children and Adolescents Treatment Panel of the National Cholesterol Education , 2004 .