Heating under high-frequency inductive conditions: application to the continuous synthesis of the neurolepticum olanzapine (Zyprexa).

[1]  Jun-ichi Yoshida,et al.  Green and sustainable chemical synthesis using flow microreactors. , 2011, ChemSusChem.

[2]  Steven J. Broadwater,et al.  The continuous-flow synthesis of Ibuprofen. , 2009, Angewandte Chemie.

[3]  J. Wegner,et al.  Flow Chemistry – A Key Enabling Technology for (Multistep) Organic Synthesis , 2012 .

[4]  Christopher G. Frost,et al.  Heterogeneous catalytic synthesis using microreactor technology , 2010 .

[5]  Andreas Kirschning,et al.  Inductive heating with magnetic materials inside flow reactors. , 2011, Chemistry.

[6]  J. Jackson,et al.  Design of potent thiophene inhibitors of polo-like kinase 1 with improved solubility and reduced protein binding. , 2009, Bioorganic & medicinal chemistry letters.

[7]  Andreas Kirschning,et al.  Ten key issues in modern flow chemistry. , 2011, Chemical communications.

[8]  Peter H Seeberger,et al.  Asymmetric reactions in continuous flow , 2009, Beilstein journal of organic chemistry.

[9]  A. Loupy,et al.  Application of Microwave Irradiation to Phase-Transfer Catalyzed Reactions , 2008 .

[10]  A. Lu,et al.  Magnetic nanoparticles: synthesis, protection, functionalization, and application. , 2007, Angewandte Chemie.

[11]  Christian Lammel,et al.  Induktives Heizen in der organischen Synthese durch Verwendung funktionalisierter magnetischer Nanopartikel in Mikroreaktoren , 2008 .

[12]  T. Turek,et al.  Flow through reactors for organic chemistry: directly electrically heated tubular mini reactors as an enabling technology for organic synthesis , 2009, Beilstein journal of organic chemistry.

[13]  Jun-ichi Yoshida,et al.  Flash chemistry: flow microreactor synthesis based on high-resolution reaction time control. , 2010, Chemical record.

[14]  F. Schüth,et al.  Magnetische Nanopartikel: Synthese, Stabilisierung, Funktionalisierung und Anwendung , 2007 .

[15]  J. McMurray,et al.  Pd-C-induced catalytic transfer hydrogenation with triethylsilane. , 2007, The Journal of organic chemistry.

[16]  A. Hallberg,et al.  Microwave-assisted high-speed chemistry: a new technique in drug discovery. , 2001, Drug discovery today.

[17]  Andreas Kirschning,et al.  Inductive heating for organic synthesis by using functionalized magnetic nanoparticles inside microreactors. , 2008, Angewandte Chemie.

[18]  J Gerlach,et al.  New antipsychotics: the present status , 1995, International clinical psychopharmacology.

[19]  A. Gagnoud,et al.  Three-dimensional integral method for modeling electromagnetic inductive processes , 2004, IEEE Transactions on Magnetics.

[20]  T. Turek,et al.  Continuous preparation of carbon-nanotube-supported platinum catalysts in a flow reactor directly heated by electric current , 2011, Beilstein journal of organic chemistry.

[21]  Andreas Kirschning,et al.  Combining enabling techniques in organic synthesis: continuous flow processes with heterogenized catalysts. , 2006, Chemistry.

[22]  C. Kappe.  Microwave dielectric heating in synthetic organic chemistry , 2008 .

[23]  C. Oliver Kappe,et al.  Continuous flow organic synthesis under high-temperature/pressure conditions. , 2010, Chemistry, an Asian journal.

[24]  M. Cheung,et al.  Regioselective synthesis of benzimidazole thiophene inhibitors of polo-like kinase 1 , 2008 .

[25]  G. Reynolds.  Receptor Mechanisms in the treatment of Schizophrenia , 2004, Journal of psychopharmacology.

[26]  Steven V Ley,et al.  A flow-based synthesis of imatinib: the API of Gleevec. , 2010, Chemical communications.

[27]  K. Jensen,et al.  Synthesis of micro and nanostructures in microfluidic systems. , 2010, Chemical Society reviews.

[28]  V. Hessel,et al.  Flow chemistry using milli- and microstructured reactors-from conventional to novel process windows. , 2010, Bioorganic & medicinal chemistry.

[29]  J. Wegner,et al.  Multistep flow synthesis of vinyl azides and their use in the copper-catalyzed Huisgen-type cycloaddition under inductive-heating conditions , 2011, Beilstein journal of organic chemistry.

[30]  Andreas Liese,et al.  Coupled chemo(enzymatic) reactions in continuous flow , 2011, Beilstein journal of organic chemistry.

[31]  G. Plosker,et al.  Olanzapine: an updated review of its use in the management of schizophrenia. , 2001, Drugs.

[32]  A. Kirschning,et al.  New Synthetic Opportunities in Miniaturized Flow Reactors with Inductive Heating , 2012 .

[33]  Klavs F Jensen,et al.  Integrated microreactors for reaction automation: new approaches to reaction development. , 2010, Annual review of analytical chemistry.

[34]  Jinwoo Cheon,et al.  Heterostructured magnetic nanoparticles: their versatility and high performance capabilities. , 2007, Chemical communications.

[35]  Young-wook Jun,et al.  The President and Society for Analytical Chemistry Gold Medallist , 1973 .

[36]  Timothy F. Jamison,et al.  Continuous flow multi-step organic synthesis , 2010 .