Acetylcholine deficit causes dysfunctional inhibitory control in an aging-dependent manner

[1]  Jaeuk U. Kim,et al.  Inhibitory Control of Saccadic Eye Movements and Cognitive Impairment in Mild Cognitive Impairment , 2022, Frontiers in Aging Neuroscience.

[2]  K. Keleman,et al.  A neural circuit linking learning and sleep in Drosophila long-term memory , 2022, Nature communications.

[3]  Nobuhiro Yamagata,et al.  Mushroom body output differentiates memory processes and distinct memory-guided behaviors , 2021, Current Biology.

[4]  Phani Garapati,et al.  FlyBase: updates to the Drosophila melanogaster knowledge base , 2020, Nucleic Acids Res..

[5]  A. Sehgal,et al.  Availability of food determines the need for sleep in memory consolidation , 2020, Nature.

[6]  B. Dubois,et al.  Cognitive and behavioural inhibition deficits in neurodegenerative dementias , 2020, Cortex.

[7]  T. Kitamoto,et al.  Deficits in the vesicular acetylcholine transporter alter lifespan and behavior in adult Drosophila melanogaster , 2020, Neurochemistry International.

[8]  Mehrab N Modi,et al.  The Drosophila Mushroom Body: From Architecture to Algorithm in a Learning Circuit. , 2020, Annual review of neuroscience.

[9]  K. Han,et al.  Concerted Actions of Octopamine and Dopamine Receptors Drive Olfactory Learning , 2020, The Journal of Neuroscience.

[10]  S. Boppana,et al.  Overexpression of the vesicular acetylcholine transporter disrupts cognitive performance and causes age-dependent locomotion decline in Drosophila , 2020, Molecular and Cellular Neuroscience.

[11]  Kristin Scott,et al.  Activation of specific mushroom body output neurons inhibits proboscis extension and sucrose consumption , 2020, PloS one.

[12]  S. Tomchik,et al.  Cellular and circuit mechanisms of olfactory associative learning in Drosophila , 2020, Journal of neurogenetics.

[13]  K. Holloway,et al.  Therapeutic approaches to cholinergic deficiency in Lewy body diseases , 2020, Expert review of neurotherapeutics.

[14]  E. Albuquerque,et al.  Evidence for positive allosteric modulation of cognitive-enhancing effects of nicotine in healthy human subjects , 2019, Psychopharmacology.

[15]  R. Khoury,et al.  Use of Cholinesterase Inhibitors in Non-Alzheimer’s Dementias , 2019, Drugs & Aging.

[16]  A. Martyr,et al.  Assessing inhibitory control in early‐stage Alzheimer's and Parkinson's disease using the Hayling Sentence Completion Test , 2019, Journal of neuropsychology.

[17]  S. Beaudin,et al.  Cholinergic and dopaminergic interactions alter attention and response inhibition in Long-Evans rats performing the 5-choice serial reaction time task , 2018, Pharmacology Biochemistry and Behavior.

[18]  Ronald L. Davis,et al.  Dopamine Neurons Mediate Learning and Forgetting through Bidirectional Modulation of a Memory Trace. , 2018, Cell reports.

[19]  M. Gade,et al.  Inhibition in aging: What is preserved? What declines? A meta-analysis , 2017, Psychonomic Bulletin & Review.

[20]  B. Al-Anzi,et al.  Identification and characterization of mushroom body neurons that regulate fat storage in Drosophila , 2018, Neural Development.

[21]  J. Wess,et al.  Muscarinic M4 Receptors on Cholinergic and Dopamine D1 Receptor-Expressing Neurons Have Opposing Functionality for Positive Reinforcement and Influence Impulsivity , 2018, Front. Mol. Neurosci..

[22]  A. Fiala,et al.  Neural Control of Startle-Induced Locomotion by the Mushroom Bodies and Associated Neurons in Drosophila , 2018, Front. Syst. Neurosci..

[23]  Suewei Lin,et al.  Drosophila mushroom bodies integrate hunger and satiety signals to control innate food-seeking behavior , 2018, eLife.

[24]  T. Tabata,et al.  Two Parallel Pathways Assign Opposing Odor Valences during Drosophila Memory Formation. , 2018, Cell reports.

[25]  J. Rowe,et al.  Neurotransmitter deficits from frontotemporal lobar degeneration , 2018, Brain : a journal of neurology.

[26]  C. Seong,et al.  The mushroom body D1 dopamine receptor controls innate courtship drive , 2017, Genes, brain, and behavior.

[27]  Scott Waddell,et al.  Cellular diversity in the Drosophila midbrain revealed by single-cell transcriptomics , 2017, bioRxiv.

[28]  Jeffrey M. Donlea,et al.  Neuronal and molecular mechanisms of sleep homeostasis. , 2017, Current opinion in insect science.

[29]  H. Otsuna,et al.  Topological and modality-specific representation of somatosensory information in the fly brain , 2017, Science.

[30]  P. Evans,et al.  Behavioral Sensitization to the Disinhibition Effect of Ethanol Requires the Dopamine/Ecdysone Receptor in Drosophila , 2017, Front. Syst. Neurosci..

[31]  Johannes Felsenberg,et al.  Re-evaluation of learned information in Drosophila , 2017, Nature.

[32]  B. S. Baker,et al.  Memory Elicited by Courtship Conditioning Requires Mushroom Body Neuronal Subsets Similar to Those Utilized in Appetitive Memory , 2016, PloS one.

[33]  M. Ananth,et al.  Basal Forebrain Cholinergic Circuits and Signaling in Cognition and Cognitive Decline , 2016, Neuron.

[34]  Steve Higham,et al.  Distinguishing between impairments of working memory and inhibitory control in cases of early dementia , 2016, Neuropsychologia.

[35]  Gerald M. Rubin,et al.  Propagation of Homeostatic Sleep Signals by Segregated Synaptic Microcircuits of the Drosophila Mushroom Body , 2015, Current Biology.

[36]  G. Rubin,et al.  Mushroom body output neurons encode valence and guide memory-based action selection in Drosophila , 2014, eLife.

[37]  J. Kenemans,et al.  Differences between nicotine-abstinent smokers and non-smokers in terms of visuospatial attention and inhibition before and after single-blind nicotine administration , 2014, Neuroscience.

[38]  S. Logue,et al.  The neural and genetic basis of executive function: Attention, cognitive flexibility, and response inhibition , 2014, Pharmacology Biochemistry and Behavior.

[39]  A. Fiala,et al.  A single dopamine pathway underlies progressive locomotor deficits in a Drosophila model of Parkinson disease. , 2013, Cell reports.

[40]  T. Robbins,et al.  Inhibition and impulsivity: Behavioral and neural basis of response control , 2013, Progress in Neurobiology.

[41]  K. Han,et al.  Appetitive Learning Requires the Alpha1-Like Octopamine Receptor OAMB in the Drosophila Mushroom Body Neurons , 2013, The Journal of Neuroscience.

[42]  L. Partridge,et al.  Ageing Increases Vulnerability to Aβ42 Toxicity in Drosophila , 2012, Alzheimer's & Dementia.

[43]  Ronald L. Davis,et al.  Aging impairs intermediate-term behavioral memory by disrupting the dorsal paired medial neuron memory trace , 2012, Proceedings of the National Academy of Sciences.

[44]  H. Mansvelder,et al.  Nicotinic Acetylcholine Receptor β2 Subunits in the Medial Prefrontal Cortex Control Attention , 2011, Science.

[45]  T. Arendt,et al.  The cholinergic system in aging and neuronal degeneration , 2011, Behavioural Brain Research.

[46]  Nele A. Haelterman,et al.  MiMIC: a highly versatile transposon insertion resource for engineering Drosophila melanogaster genes , 2011, Nature Methods.

[47]  A. Harrison,et al.  Acute nicotine increases both impulsive choice and behavioural disinhibition in rats , 2011, Psychopharmacology.

[48]  Y. Koh,et al.  Pharmacogenetic Regulation of Acetylcholinesterase Activity in Drosophila Reveals the Regulatory Mechanisms of AChE Inhibitors in Synaptic Plasticity , 2011, Neurochemical Research.

[49]  Yu Ohmura,et al.  Nicotine provokes impulsive-like action by stimulating {alpha}4{beta}2 nicotinic acetylcholine receptors in the infralimbic, but not in the prelimbic cortex , 2010 .

[50]  Yu Ohmura,et al.  Nicotine provokes impulsive-like action by stimulating α4β2 nicotinic acetylcholine receptors in the infralimbic, but not in the prelimbic cortex , 2010, Psychopharmacology.

[51]  Sylvie Belleville,et al.  Executive functions in frontotemporal dementia and Lewy body dementia. , 2009, Neuropsychology.

[52]  David J. Anderson,et al.  Distinct sensory representations of wind and near-field sound in the Drosophila brain , 2009, Nature.

[53]  Hiroki M. Morimoto,et al.  Functional dissociation in right inferior frontal cortex during performance of go/no-go task. , 2009, Cerebral cortex.

[54]  I. Martin,et al.  Genetic and environmental factors impact age-related impairment of negative geotaxis in Drosophila by altering age-dependent climbing speed , 2008, Experimental Gerontology.

[55]  M. Van der Linden,et al.  Assessing Impulsivity Changes in Alzheimer Disease , 2008, Alzheimer disease and associated disorders.

[56]  F. Collette,et al.  Comparison of Inhibitory Functioning in Mild Alzheimer's Disease and Frontotemporal Dementia , 2007, Cortex.

[57]  K. Han,et al.  D1 Dopamine Receptor dDA1 Is Required in the Mushroom Body Neurons for Aversive and Appetitive Learning in Drosophila , 2007, The Journal of Neuroscience.

[58]  I. Stolerman,et al.  Impaired performance of alpha7 nicotinic receptor knockout mice in the five-choice serial reaction time task , 2006, Psychopharmacology.

[59]  T. Crawford,et al.  Inhibitory control of saccadic eye movements and cognitive impairment in Alzheimer’s disease , 2005, Biological Psychiatry.

[60]  U. Heberlein,et al.  Habituation of an odorant‐induced startle response in Drosophila , 2004, Genes, brain, and behavior.

[61]  J. Sanes,et al.  Roles of Neurotransmitter in Synapse Formation Development of Neuromuscular Junctions Lacking Choline Acetyltransferase , 2002, Neuron.

[62]  P. Salvaterra,et al.  Localization of choline acetyltransferase‐expressing neurons in Drosophila nervous system , 1999, Microscopy research and technique.

[63]  H. Nash,et al.  The visually-induced jump response of Drosophila melanogaster is sensitive to volatile anesthetics. , 1998, Journal of neurogenetics.

[64]  M Heisenberg,et al.  Mushroom bodies suppress locomotor activity in Drosophila melanogaster. , 1998, Learning & memory.

[65]  P. Salvaterra,et al.  Analysis of choline acetyltransferase protein in temperature sensitive mutant flies using newly generated monoclonal antibody , 1996, Neuroscience Research.

[66]  L. Erlenmeyer‐Kimling,et al.  Measurement of the Relations between Chromosomes and Behavior , 1961, Science.