An obligatory role for neurotensin in high fat diet-induced obesity

[1]  D. Hardie,et al.  AMPK: positive and negative regulation, and its role in whole-body energy homeostasis. , 2015, Current opinion in cell biology.

[2]  Ronald W. Alfa,et al.  Suppression of insulin production and secretion by a decretin hormone. , 2015, Cell metabolism.

[3]  Jing Chen,et al.  Self-assembled FUS binds active chromatin and regulates gene transcription , 2014, Proceedings of the National Academy of Sciences.

[4]  K. Jiang,et al.  Hedgehog-regulated atypical PKC promotes phosphorylation and activation of Smoothened and Cubitus interruptus in Drosophila , 2014, Proceedings of the National Academy of Sciences.

[5]  N. Perrimon,et al.  Enteroendocrine cells support intestinal stem-cell-mediated homeostasis in Drosophila. , 2014, Cell reports.

[6]  N. Perrimon,et al.  Control of lipid metabolism by tachykinin in Drosophila. , 2014, Cell reports.

[7]  Julia B. Cordero,et al.  Local Control of Intestinal Stem Cell Homeostasis by Enteroendocrine Cells in the Adult Drosophila Midgut , 2014, Current Biology.

[8]  Yuhuan Wang,et al.  Mechanism of rapid elimination of lysophosphatidic acid and related lipids from the circulation of mice , 2013, Journal of Lipid Research.

[9]  A. Morris,et al.  Efficient Use of Exogenous Isoprenols for Protein Isoprenylation by MDA-MB-231 Cells Is Regulated Independently of the Mevalonate Pathway* , 2013, The Journal of Biological Chemistry.

[10]  J. Graff,et al.  Adenosine nucleotide biosynthesis and AMPK regulate adult life span and mediate the longevity benefit of caloric restriction in flies. , 2013, Cell metabolism.

[11]  P. Almgren,et al.  Plasma proneurotensin and incidence of diabetes, cardiovascular disease, breast cancer, and mortality. , 2012, JAMA.

[12]  A. Means,et al.  Calcium/Calmodulin-dependent Protein Kinase Kinase 2: Roles in Signaling and Pathophysiology* , 2012, The Journal of Biological Chemistry.

[13]  M. E. Starr,et al.  PI3K p110α/Akt signaling negatively regulates secretion of the intestinal peptide neurotensin through interference of granule transport. , 2012, Molecular endocrinology.

[14]  R. Charnigo,et al.  Adipocyte-specific deficiency of angiotensinogen decreases plasma angiotensinogen concentration and systolic blood pressure in mice. , 2012, American journal of physiology. Regulatory, integrative and comparative physiology.

[15]  J. Kwon,et al.  Heterogeneous Expression of Drosophila Gustatory Receptors in Enteroendocrine Cells , 2011, PloS one.

[16]  J. Kwon,et al.  A systematic analysis of Drosophila gustatory receptor gene expression in abdominal neurons which project to the central nervous system , 2011, Molecules and cells.

[17]  A. Lane,et al.  Stable isotope resolved metabolomics of lung cancer in a SCID mouse model , 2011, Metabolomics.

[18]  H. Weiss,et al.  mTORC1 inhibition increases neurotensin secretion and gene expression through activation of the MEK/ERK/c-Jun pathway in the human endocrine cell line BON. , 2011, American journal of physiology. Cell physiology.

[19]  R. Isaac,et al.  Peptidomics and peptide hormone processing in the Drosophila midgut. , 2011, Journal of proteome research.

[20]  Kevin A. Burns,et al.  Proneural and abdominal Hox inputs synergize to promote sensory organ formation in the Drosophila abdomen. , 2010, Developmental biology.

[21]  K. Ocorr,et al.  High-fat-diet-induced obesity and heart dysfunction are regulated by the TOR pathway in Drosophila. , 2010, Cell metabolism.

[22]  L. Groop,et al.  Plasma Copeptin and the Risk of Diabetes Mellitus , 2010, Circulation.

[23]  M. Korbonits,et al.  AMPK as a mediator of hormonal signalling. , 2010, Journal of molecular endocrinology.

[24]  S. Hou,et al.  Regulation of intestinal stem cells in mammals and Drosophila , 2010, Journal of cellular physiology.

[25]  H. Moseley,et al.  Isotopomer analysis of lipid biosynthesis by high resolution mass spectrometry and NMR. , 2009, Analytica chimica acta.

[26]  R. Shaw,et al.  The LKB1–AMPK pathway: metabolism and growth control in tumour suppression , 2009, Nature Reviews Cancer.

[27]  S. Bloom,et al.  Peripheral and Central Administration of Xenin and Neurotensin Suppress Food Intake in Rodents , 2009, Obesity.

[28]  Wei Zhang,et al.  The incidence of co-morbidities related to obesity and overweight: A systematic review and meta-analysis , 2009, BMC public health.

[29]  C. Thummel,et al.  Drosophila HNF4 regulates lipid mobilization and beta-oxidation. , 2009, Cell metabolism.

[30]  B. Edgar,et al.  EGFR signaling regulates the proliferation of Drosophila adult midgut progenitors , 2009, Development.

[31]  J. Jia,et al.  PP4 and PP2A regulate Hedgehog signaling by controlling Smo and Ci phosphorylation , 2009, Development.

[32]  G. Berglund,et al.  Lp-PLA2 activity and mass are associated with increased incidence of ischemic stroke: a population-based cohort study from Malmö, Sweden. , 2008, Atherosclerosis.

[33]  A. Means,et al.  Hypothalamic CaMKK2 contributes to the regulation of energy balance. , 2008, Cell metabolism.

[34]  C. Chen,et al.  Neurotensin increases mortality and mast cells reduce neurotensin levels in a mouse model of sepsis , 2008, Nature Medicine.

[35]  J. Jia,et al.  Fused-Costal2 protein complex regulates Hedgehog-induced Smo phosphorylation and cell-surface accumulation. , 2007, Genes & development.

[36]  A. Hipkiss On why decreasing protein synthesis can increase lifespan , 2007, Mechanisms of Ageing and Development.

[37]  B. Evers Neurotensin and growth of normal and neoplastic tissues , 2006, Peptides.

[38]  A. Deutch,et al.  Amphetamine-elicited striatal Fos expression is attenuated in neurotensin null mutant mice , 2006, Neuroscience Letters.

[39]  B. Xue,et al.  AMPK integrates nutrient and hormonal signals to regulate food intake and energy balance through effects in the hypothalamus and peripheral tissues , 2006, The Journal of physiology.

[40]  A. Bergmann,et al.  Proneurotensin 1–117, a stable neurotensin precursor fragment identified in human circulation , 2006, Peptides.

[41]  D. Chung,et al.  Protein kinase D protects against oxidative stress-induced intestinal epithelial cell injury via Rho/ROK/PKC-δ pathway activation , 2006 .

[42]  J. Shaw,et al.  Metabolic syndrome—a new world‐wide definition. A Consensus Statement from the International Diabetes Federation , 2006, Diabetic medicine : a journal of the British Diabetic Association.

[43]  A. Spradling,et al.  The adult Drosophila posterior midgut is maintained by pluripotent stem cells , 2006, Nature.

[44]  N. Perrimon,et al.  Evidence that stem cells reside in the adult Drosophila midgut epithelium , 2006, Nature.

[45]  Stéphane Martin,et al.  Neurotensin receptor-1 and -3 complex modulates the cellular signaling of neurotensin in the HT29 cell line. , 2002, Gastroenterology.

[46]  M. Adams,et al.  Identification of G protein-coupled receptors for Drosophila PRXamide peptides, CCAP, corazonin, and AKH supports a theory of ligand-receptor coevolution , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[47]  J. Seidell,et al.  Epidemiology of obesity. , 2002, Seminars in vascular medicine.

[48]  A. Deutch,et al.  Neurotensin-deficient mice show altered responses to antipsychotic drugs , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[49]  P. Taghert,et al.  Neuropeptides and neuropeptide receptors in the Drosophila melanogaster genome. , 2001, Genome research.

[50]  A. Deutch,et al.  The neurotensin antagonist SR 48692 attenuates haloperidol-induced striatal Fos expression in the rat , 2001, Neuroscience Letters.

[51]  R. Carraway,et al.  Evidence that neurotensin mediates the central effect of leptin on food intake in rat , 2001, Brain Research.

[52]  E. Richelson,et al.  A novel neurotensin peptide analog given extracranially decreases food intake and weight in rodents , 2000, Brain Research.

[53]  P. Kopelman Obesity as a medical problem , 2000, Nature.

[54]  J P Vincent,et al.  Neurotensin and neurotensin receptors. , 1999, Trends in pharmacological sciences.

[55]  P. Soubrié,et al.  SR 48692, a non-peptide neurotensin receptor antagonist differentially affects neurotensin-induced behaviour and changes in dopaminergic transmission , 1994, Neuroscience.

[56]  Professor Göran Berglund The Malmö Diet and Cancer Study Design, biological bank and biomarker programme , 1993 .

[57]  C. Ferris,et al.  Neurotensin stimulates [3H]oleic acid translocation across rat small intestine. , 1986, The American journal of physiology.

[58]  R. Turner,et al.  Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man , 1985, Diabetologia.

[59]  C. Ferris,et al.  Elevation of plasma neurotensin during lipid perfusion of rat small intestine , 1981, Peptides.

[60]  E. Ruitenberg,et al.  The ‘Swiss roll’: a simple technique for histological studies of the rodent intestine , 1981, Laboratory animals.

[61]  P. Facer,et al.  Specific localisation of neurotensin to the N cell in human intestine by radioimmunoassay and immunocytochemistry , 1977, Nature.

[62]  E. L. Springer,et al.  Epithelial cell cultures from normal and cancerous human tissues. , 1976, Journal of the National Cancer Institute.

[63]  Z. Halpern,et al.  Sortilin deficiency improves the metabolic phenotype and reduces hepatic steatosis of mice subjected to diet-induced obesity. , 2015, Journal of hepatology.

[64]  Xiaodong Cheng,et al.  Cyclic adenosine 5'-monophosphate-stimulated neurotensin secretion is mediated through Rap1 downstream of both Epac and protein kinase A signaling pathways. , 2007, Molecular endocrinology.

[65]  D. Chung,et al.  Protein kinase D protects against oxidative stress-induced intestinal epithelial cell injury via Rho/ROK/PKC-delta pathway activation. , 2006, American journal of physiology. Cell physiology.

[66]  Minisymposium: The Malmö Diet and Cancer Study. Design, biological bank and biomarker programme. 23 October 1991, Malmo, Sweden. , 1993, Journal of Internal Medicine.