Short report: serological evidence of West Nile virus activity in El Salvador.

Epizootics of encephalitis in El Salvador killed 203 equines between November 2001 and April 2003. During an investigation of the outbreaks, 18 (25%) of 73 serum samples collected from stablemates of deceased animals in 2003 had antibodies to West Nile virus. Ten of these infections were confirmed by plaque reduction neutralization tests, suggesting West Nile virus has extended its range and spread to Central America.

[1]  J. González-Rojas,et al.  Phylogenetic Analysis of West Nile Virus, Nuevo Leon State, Mexico , 2004, Emerging infectious diseases.

[2]  D. Gubler,et al.  Serologic Evidence of West Nile Virus Infection in Horses, Coahuila State, Mexico , 2003, Emerging infectious diseases.

[3]  D. Gubler,et al.  Serologic Evidence of West Nile Virus Infection in Horses, Yucatan State, Mexico , 2003, Emerging infectious diseases.

[4]  Denise A. Martin,et al.  Persistence of Virus-Reactive Serum Immunoglobulin M Antibody in Confirmed West Nile Virus Encephalitis Cases , 2003, Emerging infectious diseases.

[5]  Armando Giovannini,et al.  West Nile virus Epidemic in Horses, Tuscany Region, Italy , 2002, Emerging infectious diseases.

[6]  H. Guzmán,et al.  Immunization with Heterologous Flaviviruses Protective Against Fatal West Nile Encephalitis , 2002, Emerging infectious diseases.

[7]  K. Schmit,et al.  Dead bird surveillance as an early warning system for West Nile virus. , 2001, Emerging infectious diseases.

[8]  Randall S. Nelson,et al.  West Nile virus surveillance in Connecticut in 2000: an intense epizootic without high risk for severe human disease. , 2001, Emerging infectious diseases.

[9]  J. P. Durand,et al.  West Nile outbreak in horses in southern France, 2000: the return after 35 years. , 2001, Emerging infectious diseases.

[10]  Denise A. Martin,et al.  Standardization of Immunoglobulin M Capture Enzyme-Linked Immunosorbent Assays for Routine Diagnosis of Arboviral Infections , 2000, Journal of Clinical Microbiology.

[11]  B. Henderson,et al.  Venezuelan equine encephalomyelitis: surveys of human illness during an epizootic in Guatemala and El Salvador. , 1971, American journal of epidemiology.