Assessing the role of dopamine in the differential neurotoxicity patterns of methamphetamine, mephedrone, methcathinone and 4-methylmethamphetamine

[1]  R. Moratalla,et al.  Amphetamine-related drugs neurotoxicity in humans and in experimental animals: Main mechanisms , 2017, Progress in Neurobiology.

[2]  D. Crich,et al.  Dissecting the Influence of Two Structural Substituents on the Differential Neurotoxic Effects of Acute Methamphetamine and Mephedrone Treatment on Dopamine Nerve Endings with the Use of 4-Methylmethamphetamine and Methcathinone , 2017, The Journal of Pharmacology and Experimental Therapeutics.

[3]  Gregory G. Grecco,et al.  Cooling down the bath salts: Carvedilol attenuation of methylone and mephedrone mediated hyperthermia. , 2016, Toxicology letters.

[4]  F. Ebling,et al.  Contribution of serotonin and dopamine to changes in core body temperature and locomotor activity in rats following repeated administration of mephedrone , 2016, Addiction biology.

[5]  M. Farré,et al.  Human Pharmacology of Mephedrone in Comparison with MDMA , 2016, Neuropsychopharmacology.

[6]  M. Cole,et al.  Locomotor Stimulant and Rewarding Effects of Inhaling Methamphetamine, MDPV, and Mephedrone via Electronic Cigarette-Type Technology , 2016, Neuropsychopharmacology.

[7]  K. Murphy,et al.  Mephedrone use is increasing in London , 2016, The Lancet.

[8]  Gregory G. Grecco,et al.  Impact of Functional Group Modifications on Designer Phenethylamine Induced Hyperthermia. , 2016, Chemical research in toxicology.

[9]  Rashed Harun,et al.  Fast‐scan cyclic voltammetry demonstrates that L‐DOPA produces dose‐dependent, regionally selective bimodal effects on striatal dopamine kinetics in vivo , 2016, Journal of neurochemistry.

[10]  R. Glennon,et al.  Abuse-Related Neurochemical Effects of Para-Substituted Methcathinone Analogs in Rats: Microdialysis Studies of Nucleus Accumbens Dopamine and Serotonin , 2016, The Journal of Pharmacology and Experimental Therapeutics.

[11]  A. Górska,et al.  Effect of Some Psychoactive Drugs Used as ‘Legal Highs’ on Brain Neurotransmitters , 2015, Neurotoxicity Research.

[12]  T. Rodrigo,et al.  Neuronal changes and oxidative stress in adolescent rats after repeated exposure to mephedrone. , 2015, Toxicology and applied pharmacology.

[13]  M. Taffe,et al.  Intravenous self-administration of mephedrone, methylone and MDMA in female rats , 2015, Neuropharmacology.

[14]  D. Kuhn,et al.  3,4‐Methylenedioxypyrovalerone prevents while methylone enhances methamphetamine‐induced damage to dopamine nerve endings: β‐ketoamphetamine modulation of neurotoxicity by the dopamine transporter , 2015, Journal of neurochemistry.

[15]  R. Kronstrand,et al.  Mephedrone, Methylone and 3,4‐Methylenedioxypyrovalerone (MDPV) Induce Conditioned Place Preference in Mice , 2014, Basic & clinical pharmacology & toxicology.

[16]  E. Mervaala,et al.  Keto amphetamine toxicity-focus on the redox reactivity of the cathinone designer drug mephedrone. , 2014, Toxicological sciences : an official journal of the Society of Toxicology.

[17]  J. Camarasa,et al.  Dose and Time-Dependent Selective Neurotoxicity Induced by Mephedrone in Mice , 2014, PloS one.

[18]  B. Yamamoto,et al.  Ammonia Mediates Methamphetamine-Induced Increases in Glutamate and Excitotoxicity , 2014, Neuropsychopharmacology.

[19]  Stuart A. Collins,et al.  Neurotoxicity of methamphetamine and 3,4-methylenedioxymethamphetamine. , 2014, Life sciences.

[20]  B. Yamamoto,et al.  Methamphetamine causes acute hyperthermia-dependent liver damage , 2013, Pharmacology research & perspectives.

[21]  A. Janowsky,et al.  Substituted methcathinones differ in transporter and receptor interactions. , 2013, Biochemical pharmacology.

[22]  J. Ramsey,et al.  High levels of intravenous mephedrone (4-methylmethcathinone) self-administration in rats: Neural consequences and comparison with methamphetamine , 2013, Journal of psychopharmacology.

[23]  M. Kane,et al.  Mephedrone does not damage dopamine nerve endings of the striatum, but enhances the neurotoxicity of methamphetamine, amphetamine, and MDMA , 2013, Journal of neurochemistry.

[24]  A. Green,et al.  Differential effects of cathinone compounds and MDMA on body temperature in the rat, and pharmacological characterization of mephedrone‐induced hypothermia , 2013, British journal of pharmacology.

[25]  R. Glennon,et al.  Mephedrone and methylenedioxypyrovalerone (MDPV), major constituents of “bath salts,” produce opposite effects at the human dopamine transporter , 2013, Psychopharmacology.

[26]  S. Rozov,et al.  Long-term cognitive and neurochemical effects of “bath salt” designer drugs methylone and mephedrone , 2013, Pharmacology Biochemistry and Behavior.

[27]  M. Liechti,et al.  Pharmacological characterization of designer cathinones in vitro , 2013, British journal of pharmacology.

[28]  Wei Xu,et al.  Mephedrone ('bath salt') elicits conditioned place preference and dopamine-sensitive motor activation. , 2012, Drug and alcohol dependence.

[29]  B. Blough,et al.  Effects of synthetic cathinones contained in "bath salts" on motor behavior and a functional observational battery in mice. , 2012, Neurotoxicology.

[30]  B. Yamamoto,et al.  Peripheral Ammonia as a Mediator of Methamphetamine Neurotoxicity , 2012, The Journal of Neuroscience.

[31]  J. Camarasa,et al.  Comparative neuropharmacology of three psychostimulant cathinone derivatives: butylone, mephedrone and methylone , 2012, British journal of pharmacology.

[32]  L. Parsons,et al.  Effect of Ambient Temperature on the Thermoregulatory and Locomotor Stimulant Effects of 4-Methylmethcathinone in Wistar and Sprague-Dawley Rats , 2012, PloS one.

[33]  K. Blakey,et al.  GC-MS and GC-IRD analysis of 2-, 3- and 4-methylmethamphetamine and 2-, 3- and 4-methylamphetamine. , 2012, Forensic science international.

[34]  R. Rothman,et al.  The Designer Methcathinone Analogs, Mephedrone and Methylone, are Substrates for Monoamine Transporters in Brain Tissue , 2012, Neuropsychopharmacology.

[35]  D. Kuhn,et al.  Mephedrone, an abused psychoactive component of ‘bath salts’ and methamphetamine congener, does not cause neurotoxicity to dopamine nerve endings of the striatum , 2012, Journal of neurochemistry.

[36]  I. McGregor,et al.  Mephedrone (4‐methylmethcathinone, ‘meow’): acute behavioural effects and distribution of Fos expression in adolescent rats , 2012, Addiction biology.

[37]  G. Hanson,et al.  4-Methylmethcathinone (Mephedrone): Neuropharmacological Effects of a Designer Stimulant of Abuse , 2011, Journal of Pharmacology and Experimental Therapeutics.

[38]  D. Kuhn,et al.  Increases in cytoplasmic dopamine compromise the normal resistance of the nucleus accumbens to methamphetamine neurotoxicity , 2009, Journal of neurochemistry.

[39]  D. Kuhn,et al.  Dopamine Disposition in the Presynaptic Process Regulates the Severity of Methamphetamine‐Induced Neurotoxicity , 2008, Annals of the New York Academy of Sciences.

[40]  P. Emson,et al.  Reduced vesicular storage of dopamine exacerbates methamphetamine‐induced neurodegeneration and astrogliosis , 2008, Journal of neurochemistry.

[41]  B. Yamamoto,et al.  The Role of Oxidative Stress, Metabolic Compromise, and Inflammation in Neuronal Injury Produced by Amphetamine-Related Drugs of Abuse , 2008, Journal of Neuroimmune Pharmacology.

[42]  D. Kuhn,et al.  The newly synthesized pool of dopamine determines the severity of methamphetamine‐induced neurotoxicity , 2008, Journal of neurochemistry.

[43]  J. Benjamins,et al.  Methamphetamine Neurotoxicity in Dopamine Nerve Endings of the Striatum Is Associated with Microglial Activation , 2004, Journal of Pharmacology and Experimental Therapeutics.

[44]  D. Kuhn,et al.  Microglial activation is a pharmacologically specific marker for the neurotoxic amphetamines , 2004, Neuroscience Letters.

[45]  T. Guilarte,et al.  Methamphetamine-induced deficits of brain monoaminergic neuronal markers: distal axotomy or neuronal plasticity , 2003, Neuroscience.

[46]  M. Pallàs,et al.  Different glial response to methamphetamine- and methylenedioxymethamphetamine-induced neurotoxicity , 2003, Naunyn-Schmiedeberg's Archives of Pharmacology.

[47]  U. McCann,et al.  Effect of Temperature on Dopamine Transporter Function and Intracellular Accumulation of Methamphetamine: Implications for Methamphetamine-Induced Dopaminergic Neurotoxicity , 2000, The Journal of Neuroscience.

[48]  M. Colado,et al.  Studies on the role of dopamine in the degeneration of 5‐HT nerve endings in the brain of Dark Agouti rats following 3,4‐methylenedioxymethamphetamine (MDMA or ‘ecstasy’) administration , 1999, British journal of pharmacology.

[49]  M. Gygi,et al.  Role of endogenous dopamine in the neurochemical deficits induced by methcathinone. , 1997, The Journal of pharmacology and experimental therapeutics.

[50]  R. Rockhold,et al.  Methcathinone intoxication in the rat: abrogation by dextrorphan. , 1997, Annals of emergency medicine.

[51]  G. Ricaurte,et al.  Neurotoxic and pharmacologic studies on enantiomers of the N-methylated analog of cathinone (methcathinone): a new drug of abuse. , 1996, The Journal of pharmacology and experimental therapeutics.

[52]  M. Gygi,et al.  Methcathinone: an initial study of its effects on monoaminergic systems. , 1996, The Journal of pharmacology and experimental therapeutics.

[53]  F. Thibaut,et al.  Pharmacological modifications of dopamine transmission do not influence the striatal in vivo binding of [3H]mazindol or [3H]cocaine in mice , 1996, Neuroscience Letters.

[54]  L. King,et al.  Effects of pargyline and pyrogallol on the methamphetamine-induced dopamine depletion. , 1995, Molecular and chemical neuropathology.

[55]  W. Slikker,et al.  Low environmental temperatures or pharmacologic agents that produce hypothermia decrease methamphetamine neurotoxicity in mice , 1994, Brain Research.

[56]  J. O'Callaghan,et al.  Environment-, drug- and stress-induced alterations in body temperature affect the neurotoxicity of substituted amphetamines in the C57BL/6J mouse. , 1994, The Journal of pharmacology and experimental therapeutics.

[57]  G. Arbuthnott,et al.  Amphetamine‐Induced Dopamine Release in the Rat Striatum: An In Vivo Microdialysis Study , 1988, Journal of neurochemistry.

[58]  M. Billingsley,et al.  Tyrosine hydroxylase: purification from PC-12 cells, characterization and production of antibodies , 1987, Neurochemistry International.

[59]  Gerald Gianutsos,et al.  Drug-induced changes in motor activity after selective MAO inhibition , 1983, Pharmacology Biochemistry and Behavior.

[60]  W. Gerrard Effect of Temperature , 1976 .