This information is current as Mechanism Responsiveness , Acts by a Cell-Autonomous a Locus Controlling IL-12 Tpm 1

[1]  K. Murphy,et al.  T cell genetic background determines maintenance of IL-12 signaling: effects on BALB/c and B10.D2 T helper cell type 1 phenotype development. , 1997, Journal of immunology.

[2]  K. Murphy,et al.  Genetic control of Interleukin 12 responsiveness: implications for disease pathogenesis , 1997, Journal of Molecular Medicine.

[3]  T. Mak,et al.  Interferon regulatory factor-1 is required for a T helper 1 immune response in vivo. , 1997, Immunity.

[4]  T. Taniguchi,et al.  Multistage regulation of Th1-type immune responses by the transcription factor IRF-1. , 1997, Immunity.

[5]  N. Schork,et al.  Serial backcross mapping of multiple loci associated with resistance to Leishmania major in mice. , 1997, Immunity.

[6]  M. Daly,et al.  Genetic mapping of a murine locus controlling development of T helper 1/T helper 2 type responses. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[7]  Eric S. Lander,et al.  A comprehensive genetic map of the mouse genome , 1996, Nature.

[8]  W. Dietrich,et al.  Genetic Susceptibility to Leishmania: IL-12 Responsiveness in TH1 Cell Development , 1996, Science.

[9]  R. Locksley,et al.  Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity [published erratum appears in J Exp Med 1997 May 5;185(9):1715] , 1996, The Journal of experimental medicine.

[10]  D. Baker,et al.  Genetic analysis of experimental allergic encephalomyelitis in mice. , 1995, Journal of immunology.

[11]  D. Postma,et al.  Genetic susceptibility to asthma--bronchial hyperresponsiveness coinherited with a major gene for atopy. , 1995, The New England journal of medicine.

[12]  D. Meyers,et al.  Approaches to mapping genes for allergy and asthma. , 1995, American journal of respiratory and critical care medicine.

[13]  S. Szabo,et al.  Developmental commitment to the Th2 lineage by extinction of IL-12 signaling. , 1995, Immunity.

[14]  A. Sette,et al.  Altered peptide ligands can control CD4 T lymphocyte differentiation in vivo , 1995, The Journal of experimental medicine.

[15]  Hans Clevers,et al.  An HMG-box-containing T-cell factor required for thymocyte differentiation , 1995, Nature.

[16]  R. Titus,et al.  T cell and non-T cell compartments can independently determine resistance to Leishmania major , 1995, The Journal of experimental medicine.

[17]  C. Hsieh,et al.  T cell genetic background determines default T helper phenotype development in vitro , 1995, The Journal of experimental medicine.

[18]  S. Romagnani,et al.  Regulation of the development of type 2 T-helper cells in allergy. , 1994, Current opinion in immunology.

[19]  N. Morton,et al.  Genetic analysis of atopy and asthma as quantitative traits and ordered polychotomies , 1994, Annals of human genetics.

[20]  D. Postma,et al.  Evidence for a locus regulating total serum IgE levels mapping to chromosome 5. , 1994, Genomics.

[21]  H. Weiner,et al.  Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. , 1994, Science.

[22]  Eric S. Lander,et al.  A genetic map of the mouse with 4,006 simple sequence length polymorphisms , 1994, Nature Genetics.

[23]  J. D. Neely,et al.  Linkage analysis of IL4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations. , 1994, Science.

[24]  H. Mcdevitt,et al.  A role for non-MHC genetic polymorphism in susceptibility to spontaneous autoimmunity. , 1994, Immunity.

[25]  R. Locksley,et al.  Leishmania promastigotes evade interleukin 12 (IL-12) induction by macrophages and stimulate a broad range of cytokines from CD4+ T cells during initiation of infection , 1994, The Journal of experimental medicine.

[26]  A. Sher,et al.  Interleukin 12 acts directly on CD4+ T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such priming. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[27]  M. Potter,et al.  GENETIC CONTROL OF LEISHMANIA MAJOR INFECTION IN CONGENIC, RECOMBINANT INBRED AND F2 POPULATIONS OF MICE , 1993, European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics.

[28]  D. Largaespada,et al.  Structural comparison and chromosomal localization of the human and mouse IL-13 genes. , 1993, Journal of immunology.

[29]  R. Schaub,et al.  Resolution of cutaneous leishmaniasis: interleukin 12 initiates a protective T helper type 1 immune response , 1993, The Journal of experimental medicine.

[30]  R. Rerko,et al.  Recombinant interleukin 12 cures mice infected with Leishmania major , 1993, The Journal of experimental medicine.

[31]  C. Hsieh,et al.  Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages. , 1993, Science.

[32]  C. Hsieh,et al.  Pathogen-induced Th1 phenotype development in CD4+ αβ-TCR transgenic T cells is macrophage dependent , 1993 .

[33]  G. Trinchieri,et al.  Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells , 1993, The Journal of experimental medicine.

[34]  S. Desiderio,et al.  itk, a T-cell-specific tyrosine kinase gene inducible by interleukin 2. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[35]  M. Lovett,et al.  The selective isolation of novel cDNAs encoded by the regions surrounding the human interleukin 4 and 5 genes. , 1992, Nucleic acids research.

[36]  W. Paul,et al.  The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice , 1992, The Journal of experimental medicine.

[37]  E S Lander,et al.  A genetic map of the mouse suitable for typing intraspecific crosses. , 1992, Genetics.

[38]  M. de Carli,et al.  Reciprocal regulatory effects of IFN-gamma and IL-4 on the in vitro development of human Th1 and Th2 clones. , 1992, Journal of immunology.

[39]  R. Coffman,et al.  IL-4 induces a Th2 response in Leishmania major-infected mice. , 1992, Journal of immunology.

[40]  S. Durham,et al.  Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma. , 1992, The New England journal of medicine.

[41]  J. Merrill,et al.  Inflammatory leukocytes and cytokines in the peptide-induced disease of experimental allergic encephalomyelitis in SJL and B10.PL mice. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[42]  A. Weinberg,et al.  Transforming growth factor-beta and IL-4 cause helper T cell precursors to develop into distinct effector helper cells that differ in lymphokine secretion pattern and cell surface phenotype. , 1991, Journal of immunology.

[43]  R. Locksley,et al.  Production of interferon gamma, interleukin 2, interleukin 4, and interleukin 10 by CD4+ lymphocytes in vivo during healing and progressive murine leishmaniasis. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[44]  Soumitra Ghosh,et al.  Genetic analysis of autoimmune type 1 diabetes mellitus in mice , 1991, Nature.

[45]  M. Piccinni,et al.  Allergen- and bacterial antigen-specific T-cell clones established from atopic donors show a different profile of cytokine production. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[46]  R. Locksley,et al.  Helper T-cell subsets in mouse leishmaniasis: induction, expansion and effector function. , 1991, Immunology today.

[47]  A. Heimberger,et al.  Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo. , 1990, Science.

[48]  A. Weinberg,et al.  IL-4 directs the development of Th2-like helper effectors. , 1990, Journal of immunology.

[49]  W. Paul,et al.  Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4- producing cells , 1990, The Journal of experimental medicine.

[50]  P. D’Eustachio,et al.  Clustering of cytokine genes on mouse chromosome 11 , 1990, The Journal of experimental medicine.

[51]  R. Locksley,et al.  Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism , 1990, The Journal of experimental medicine.

[52]  M. Belosevic,et al.  Administration of monoclonal anti-IFN-gamma antibodies in vivo abrogates natural resistance of C3H/HeN mice to infection with Leishmania major. , 1989, Journal of immunology.

[53]  R. Locksley,et al.  Powered by the California Digital Library University of California RECIPROCAL EXPRESSION OF INTERFERON y OR INTERLEUKIN 4 DURING THE RESOLUTION OR PROGRESSION OF MURINE LEISHMANIASIS Evidence for Expansion of Distinct Helper T Cell Subsets , 2003 .

[54]  R. Coffman,et al.  Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens , 1988, The Journal of experimental medicine.

[55]  T. Taniguchi,et al.  Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN-β gene regulatory elements , 1988, Cell.

[56]  R. Coffman,et al.  Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. , 1986, Journal of immunology.

[57]  R. Locksley,et al.  Murine cutaneous leishmaniasis: resistance correlates with the capacity to generate interferon-gamma in response to Leishmania antigens in vitro. , 1986, Journal of immunology.

[58]  P. Marrack,et al.  The major histocompatibility complex-restricted antigen receptor on T cells. IV. An antiidiotypic antibody predicts both antigen and I- specificity , 1983, The Journal of experimental medicine.

[59]  D. Katz,et al.  Regulation of IgE antibody production by serum molecules. II. Strain-specificity of the suppressive activity of serum from complete freund's adjuvant-immune low responder mouse donors. , 1978, Journal of immunology.

[60]  K. Silverman,et al.  Mouse Chromosome 11 , 1999, Mammalian Genome.

[61]  S. Constant,et al.  Induction of Th1 and Th2 CD4+ T cell responses: the alternative approaches. , 1997, Annual review of immunology.

[62]  J. Howard.  Immunological regulation and control of experimental leishmaniasis. , 1986, International review of experimental pathology.

[63]  N. Vaz,et al.  Effect of combinations of inbred strain, antigen, and antigen dose on immune responsiveness and reagin production in the mouse. A potential mouse model for immune aspects of human atopic allergy. , 1970, International archives of allergy and applied immunology.

[64]  C. Hsieh,et al.  Differential regulation of T helper phenotype development by interleukins 4 and 10 in an c43 T-cell-receptor transgenic system , 2022 .