Prediction of Human Pharmacokinetics From Preclinical Information: Comparative Accuracy of Quantitative Prediction Approaches
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Bill J Smith | T. Maurer | K. Beaumont | W. Collard | Hannah Jones | H. Jones | R. Webster | N. Hosea | S. Cole | S. Kakar | Yasuhiro Nakai | Rob Webster | Kevin Beaumont | Natilie A Hosea | Wendy T Collard | Susan Cole | Tristan S Maurer | Rick X Fang | Shefali M Kakar | Y. Nakai | Bill Smith | Rick X. Fang
[1] J B Houston,et al. Utility of in vitro drug metabolism data in predicting in vivo metabolic clearance. , 1994, Biochemical pharmacology.
[2] C C Travis,et al. Interspecific scaling of toxicity data. , 1988, Risk analysis : an official publication of the Society for Risk Analysis.
[3] Huadong Tang,et al. A NOVEL MODEL FOR PREDICTION OF HUMAN DRUG CLEARANCE BY ALLOMETRIC SCALING , 2005, Drug Metabolism and Disposition.
[4] A. Barve,et al. Linear Correlation of the Fraction of Oral Dose Absorbed of 64 Drugs Between Humans and Rats , 1998, Pharmaceutical Research.
[5] Franco Lombardo,et al. Trend Analysis of a Database of Intravenous Pharmacokinetic Parameters in Humans for 670 Drug Compounds , 2008, Drug Metabolism and Disposition.
[6] Michael Mayersohn,et al. A global examination of allometric scaling for predicting human drug clearance and the prediction of large vertical allometry. , 2006, Journal of pharmaceutical sciences.
[7] K. Bachmann,et al. Scaling basic toxicokinetic parameters from rat to man. , 1996, Environmental health perspectives.
[8] R. Riley,et al. The pivotal role of hepatocytes in drug discovery. , 2007, Chemico-biological interactions.
[9] P. Hinderling,et al. Red blood cells: a neglected compartment in pharmacokinetics and pharmacodynamics. , 1997, Pharmacological reviews.
[10] D J Rance,et al. The prediction of human pharmacokinetic parameters from preclinical and in vitro metabolism data. , 1997, The Journal of pharmacology and experimental therapeutics.
[11] Keith W Ward,et al. A comprehensive quantitative and qualitative evaluation of extrapolation of intravenous pharmacokinetic parameters from rat, dog, and monkey to humans. II. Volume of distribution and mean residence time. , 2004, Drug metabolism and disposition: the biological fate of chemicals.
[12] T Ishizaki,et al. Prediction of in vivo drug metabolism in the human liver from in vitro metabolism data. , 1997, Pharmacology & therapeutics.
[13] W. L. Chiou,et al. Similarity in the linear and non-linear oral absorption of drugs between human and rat. , 2000, International journal of clinical pharmacology and therapeutics.
[14] K. S. Sidhu. Basis for body weight exponent (0.75) as a scaling factor in energy metabolism and risk assessment , 1992, Journal of applied toxicology : JAT.
[15] H. Boxenbaum,et al. Effective Half‐Life in Clinical Pharmacology , 1995, Journal of clinical pharmacology.
[16] U. Fagerholm. Prediction of human pharmacokinetics—evaluation of methods for prediction of hepatic metabolic clearance , 2007, The Journal of pharmacy and pharmacology.
[17] Kiyomi Ito,et al. Prediction of Human Drug Clearance from in Vitro and Preclinical Data Using Physiologically Based and Empirical Approaches , 2004, Pharmaceutical Research.
[18] J. Wagner. Dosage intervals based on mean residence times. , 1987, Journal of pharmaceutical sciences.
[19] Ken Grime,et al. Use of Hepatocytes to Assess the Contribution of Hepatic Uptake to Clearance in Vivo , 2007, Drug Metabolism and Disposition.
[20] Y. Sugiyama,et al. Vectorial Transport of Enalapril by Oatp1a1/Mrp2 and OATP1B1 and OATP1B3/MRP2 in Rat and Human Livers , 2006, Journal of Pharmacology and Experimental Therapeutics.
[21] G. Robbie,et al. Correlation of Plasma Clearance of 54 Extensively Metabolized Drugs Between Humans and Rats: Mean Allometric Coefficient of 0.66 , 1998, Pharmaceutical Research.
[22] Y. Sawada,et al. Hepatic drug clearance model: comparison among the distributed, parallel-tube and well-stirred models. , 1985, Chemical and pharmaceutical bulletin.
[23] P. Hinderling. Kinetics of partitioning and binding of digoxin and its analogues in the subcompartments of blood. , 1984, Journal of pharmaceutical sciences.
[24] Robert L. Dedrick,et al. Animal scale-up , 1973, Journal of Pharmacokinetics and Biopharmaceutics.
[25] J. Balian,et al. Interspecies scaling: predicting clearance of drugs in humans. Three different approaches. , 1996, Xenobiotica; the fate of foreign compounds in biological systems.
[26] Michael J Banker,et al. Development and validation of a 96-well equilibrium dialysis apparatus for measuring plasma protein binding. , 2003, Journal of pharmaceutical sciences.
[27] Keith W Ward,et al. A comprehensive analysis of the role of correction factors in the allometric predictivity of clearance from rat, dog, and monkey to humans. , 2004, Journal of pharmaceutical sciences.
[28] L. Benet,et al. IN VITRO AND IN VIVO CORRELATION OF HEPATIC TRANSPORTER EFFECTS ON ERYTHROMYCIN METABOLISM: CHARACTERIZING THE IMPORTANCE OF TRANSPORTER-ENZYME INTERPLAY , 2006, Drug Metabolism and Disposition.
[29] Correlation of Unbound Plasma Clearances of Fifteen Extensively Metabolized Drugs Between Humans and Rats , 1988, Pharmaceutical Research.
[30] T Lavé,et al. Prediction of Hepatic Metabolic Clearance Based on Interspecies Allometric Scaling Techniques and In Vitro-In Vivo Correlations , 1999, Clinical pharmacokinetics.
[31] E. Adolph,et al. Quantitative Relations in the Physiological Constitutions of Mammals. , 1949, Science.
[32] Mauricio Leal,et al. Interspecies Prediction of Human Drug Clearance Based on Scaling Data from One or Two Animal Species , 2007, Drug Metabolism and Disposition.
[33] Ho-Chul Shin,et al. Why is it Challenging to Predict Intestinal Drug Absorption and Oral Bioavailability in Human Using Rat Model , 2006, Pharmaceutical Research.
[34] B. Burchell,et al. In vitro analysis of human drug glucuronidation and prediction of in vivo metabolic clearance. , 2002, The Journal of pharmacology and experimental therapeutics.
[35] M. Kleiber. Metabolic turnover rate: a physiological meaning of the metabolic rate per unit body weight. , 1975, Journal of theoretical biology.
[36] S. Ekins,et al. Comparative Pharmacophore Modeling of Organic Anion Transporting Polypeptides: A Meta-Analysis of Rat Oatp1a1 and Human OATP1B1 , 2005, Journal of Pharmacology and Experimental Therapeutics.
[37] R Scott Obach,et al. Drug metabolism and drug interactions: application and clinical value of in vitro models. , 2003, Current drug metabolism.
[38] Keith W Ward,et al. A comprehensive quantitative and qualitative evaluation of extrapolation of intravenous pharmacokinetic parameters from rat, dog, and monkey to humans. I. Clearance. , 2004, Drug metabolism and disposition: the biological fate of chemicals.
[39] H. Boxenbaum. Literature growth in pharmacokinetics , 1982, Journal of Pharmacokinetics and Biopharmaceutics.
[40] Peter J H Webborn,et al. Prediction of the Pharmacokinetics of Atorvastatin, Cerivastatin, and Indomethacin Using Kinetic Models Applied to Isolated Rat Hepatocytes , 2008, Drug Metabolism and Disposition.
[41] H. Boxenbaum. Interspecies variation in liver weight, hepatic blood flow, and antipyrine intrinsic clearance: Extrapolation of data to benzodiazepines and phenytoin , 1980, Journal of Pharmacokinetics and Biopharmaceutics.
[42] Johan Gabrielsson,et al. Pharmacokinetic and Pharmacodynamic Data Analysis: Concepts and Applications , 2002 .
[43] R C Chou,et al. Integration of in vitro data into allometric scaling to predict hepatic metabolic clearance in man: application to 10 extensively metabolized drugs. , 1997, Journal of pharmaceutical sciences.
[44] S Oie,et al. Effect of altered plasma protein binding on apparent volume of distribution. , 1979, Journal of pharmaceutical sciences.
[45] K. C. Kwan. Oral bioavailability and first-pass effects. , 1997, Drug metabolism and disposition: the biological fate of chemicals.
[46] J. Mordenti,et al. Man versus beast: pharmacokinetic scaling in mammals. , 1986, Journal of pharmaceutical sciences.
[47] H. Kusuhara,et al. Is the Monkey an Appropriate Animal Model to Examine Drug-Drug Interactions Involving Renal Clearance? Effect of Probenecid on the Renal Elimination of H2 Receptor Antagonists , 2006, Journal of Pharmacology and Experimental Therapeutics.
[48] L. Benet,et al. Hepatic microsome studies are insufficient to characterize in vivo hepatic metabolic clearance and metabolic drug-drug interactions: studies of digoxin metabolism in primary rat hepatocytes versus microsomes. , 2004, Drug metabolism and disposition: the biological fate of chemicals.