Th17 cytokines differentiate obesity from obesity-associated type 2 diabetes and promote TNFα production

T cell inflammation plays pivotal roles in obesity‐associated type 2 diabetes (T2DM). The identification of dominant sources of T cell inflammation in humans remains a significant gap in understanding disease pathogenesis. It was hypothesized that cytokine profiles from circulating T cells identify T cell subsets and T cell cytokines that define T2DM‐associated inflammation.

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