MPO-ANCA induces IL-17 production by activated neutrophils in vitro via classical complement pathway-dependent manner.

[1]  K. Suzuki,et al.  Nanocrystal Quantum Dot-Conjugated Anti-Myeloperoxidase Antibody as the Detector of Activated Neutrophils , 2007, IEEE Transactions on NanoBioscience.

[2]  D. Levy,et al.  IL-6 programs TH-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways , 2007, Nature Immunology.

[3]  A. D. Panopoulos,et al.  Essential autocrine regulation by IL-21 in the generation of inflammatory T cells , 2007, Nature.

[4]  Terry B. Strom,et al.  IL-21 initiates an alternative pathway to induce proinflammatory TH17 cells , 2007, Nature.

[5]  J. Ruland,et al.  Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17 , 2007, Nature Immunology.

[6]  R. Medzhitov,et al.  Antifungal defense turns 17 , 2007, Nature Immunology.

[7]  Hiroshi Hashimoto,et al.  Trafficking of QD‐Conjugated MPO‐ANCA in Murine Systemic Vasculitis and Glomerulonephritis Model Mice , 2007, Microbiology and immunology.

[8]  H. Okamura,et al.  Neutrophil activation and arteritis induced by C. albicans water-soluble mannoprotein-β-glucan complex (CAWS) , 2007, Experimental and Molecular Pathology.

[9]  J. Albina,et al.  β-Glucan Is a Fungal Determinant for Adhesion-Dependent Human Neutrophil Functions1 , 2006, The Journal of Immunology.

[10]  Kazuo Suzuki,et al.  Up-regulation of adhesion molecule expression in glomerular endothelial cells by anti-myeloperoxidase antibody. , 2006, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[11]  Kazuo Suzuki,et al.  Beta-mannosyl linkages negatively regulate anaphylaxis and vasculitis in mice, induced by CAWS, fungal PAMPS composed of mannoprotein-beta-glucan complex secreted by Candida albicans. , 2006, Biological & pharmaceutical bulletin.

[12]  J. Ravetch,et al.  Anti-Inflammatory Activity of Immunoglobulin G Resulting from Fc Sialylation , 2006, Science.

[13]  Kazuo Suzuki,et al.  Genetic Dissection of Vasculitis, Myeloperoxidase-Specific Antineutrophil Cytoplasmic Autoantibody Production, and Related Traits in Spontaneous Crescentic Glomerulonephritis-Forming/Kinjoh Mice1 , 2006, The Journal of Immunology.

[14]  R. Grillot,et al.  Human Dendritic Cells following Aspergillus fumigatus Infection Express the CCR7 Receptor and a Differential Pattern of Interleukin-12 (IL-12), IL-23, and IL-27 Cytokines, Which Lead to a Th1 Response , 2006, Infection and Immunity.

[15]  T. Mcclanahan,et al.  IL-23 Enhances the Inflammatory Cell Response in Cryptococcus neoformans Infection and Induces a Cytokine Pattern Distinct from IL-121 , 2006, The Journal of Immunology.

[16]  P. Heeringa,et al.  Anti-neutrophil cytoplasmic autoantibodies and leukocyte-endothelial interactions: a sticky connection? , 2005, Trends in immunology.

[17]  S. Nourshargh,et al.  Antineutrophil cytoplasm antibodies directed against myeloperoxidase augment leukocyte-microvascular interactions in vivo. , 2005, Blood.

[18]  S. Gordon,et al.  Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C type lectins. , 2005, Immunity.

[19]  P. Mastrantonio,et al.  Bordetella pertussis-Infected Human Monocyte-Derived Dendritic Cells Undergo Maturation and Induce Th1 Polarization and Interleukin-23 Expression , 2005, Infection and Immunity.

[20]  T. Mcclanahan,et al.  IL-23 drives a pathogenic T cell population that induces autoimmune inflammation , 2005, The Journal of experimental medicine.

[21]  Kazuo Suzuki,et al.  Intravenous immunoglobulin (IVIg) therapy in MPO-ANCA related polyangiitis with rapidly progressive glomerulonephritis in Japan. , 2004, Japanese journal of infectious diseases.

[22]  A. Lindén,et al.  Interleukin-17 family members and inflammation. , 2004, Immunity.

[23]  P. Schwarzenberger,et al.  Requirement of interleukin-17A for systemic anti-Candida albicans host defense in mice. , 2004, The Journal of infectious diseases.

[24]  Kazuo Suzuki,et al.  Neutrophil contribution to the crescentic glomerulonephritis in SCG/Kj mice. , 2004, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[25]  H. Smits,et al.  Commensal Gram‐negative bacteria prime human dendritic cells for enhanced IL‐23 and IL‐27 expression and enhanced Th1 development , 2004, European journal of immunology.

[26]  A. Zychlinsky,et al.  Neutrophil Extracellular Traps Kill Bacteria , 2004, Science.

[27]  T. Mcclanahan,et al.  Divergent Pro- and Antiinflammatory Roles for IL-23 and IL-12 in Joint Autoimmune Inflammation , 2003, The Journal of experimental medicine.

[28]  T. Luft,et al.  Functional comparison of DCs generated in vivo with Flt3 ligand or in vitro from blood monocytes: differential regulation of function by specific classes of physiologic stimuli. , 2003, Blood.

[29]  R. Misra,et al.  Bactericidal/permeability-increasing protein and cathepsin G are the major antigenic targets of antineutrophil cytoplasmic autoantibodies in systemic sclerosis. , 2003, The Journal of rheumatology.

[30]  S. Gordon,et al.  Dectin-1 Mediates the Biological Effects of β-Glucans , 2003, The Journal of experimental medicine.

[31]  Shizuo Akira,et al.  Collaborative Induction of Inflammatory Responses by Dectin-1 and Toll-like Receptor 2 , 2003, The Journal of experimental medicine.

[32]  E. Csernok Anti-neutrophil cytoplasmic antibodies and pathogenesis of small vessel vasculitides. , 2003, Autoimmunity reviews.

[33]  J. Shellito,et al.  Cutting Edge: Roles of Toll-Like Receptor 4 and IL-23 in IL-17 Expression in Response to Klebsiella pneumoniae Infection1 , 2003, The Journal of Immunology.

[34]  S. Ferretti,et al.  IL-17, Produced by Lymphocytes and Neutrophils, Is Necessary for Lipopolysaccharide-Induced Airway Neutrophilia: IL-15 as a Possible Trigger , 2003, The Journal of Immunology.

[35]  S. Horie,et al.  Effect of CAWS, a mannoprotein-beta-glucan complex of Candida albicans, on leukocyte, endothelial cell, and platelet functions in vitro. , 2003, Biological & pharmaceutical bulletin.

[36]  Kazuo Suzuki,et al.  Myeloperoxidase has Directly-opposed Effects on Nitration Reaction--Study on Myeloperoxidase-deficient Patient and Myeloperoxidase-knockout Mice , 2003, Free radical research.

[37]  Haruo Watanabe,et al.  Relative contributions of myeloperoxidase and NADPH-oxidase to the early host defense against pulmonary infections with Candida albicans and Aspergillus fumigatus. , 2002, Medical mycology.

[38]  P. Heeringa,et al.  Antineutrophil cytoplasmic autoantibodies specific for myeloperoxidase cause glomerulonephritis and vasculitis in mice. , 2002, The Journal of clinical investigation.

[39]  Siamon Gordon,et al.  Dectin-1 Is A Major β-Glucan Receptor On Macrophages , 2002, The Journal of experimental medicine.

[40]  Haruo Watanabe,et al.  Critical role of myeloperoxidase and nicotinamide adenine dinucleotide phosphate-oxidase in high-burden systemic infection of mice with Candida albicans. , 2002, The Journal of infectious diseases.

[41]  A. Bollen,et al.  Human recombinant myeloperoxidase antiviral activity on cytomegalovirus , 2002, Journal of medical virology.

[42]  Kazuo Suzuki,et al.  Contribution of Myeloperoxidase to Coronary Artery Vasculitis Associated with MPO-ANCA Production , 2001, Inflammation.

[43]  S. Gordon,et al.  Characterization of the Human β-Glucan Receptor and Its Alternatively Spliced Isoforms* , 2001, The Journal of Biological Chemistry.

[44]  M. Drayson,et al.  IgG from myeloperoxidase-antineutrophil cytoplasmic antibody-positive patients stimulates greater activation of primed neutrophils than IgG from proteinase 3-antineutrophil cytosplasmic antibody-positive patients. , 2001, Arthritis and rheumatism.

[45]  H. Koyama,et al.  Differential host susceptibility to pulmonary infections with bacteria and fungi in mice deficient in myeloperoxidase. , 2000, The Journal of infectious diseases.

[46]  Y. Adachi,et al.  Chemical and immunochemical characterization of limulus factor G-activating substance of Candida spp. , 1999, FEMS immunology and medical microbiology.

[47]  G. Johnson,et al.  Mapping of the C5a receptor signal transduction network in human neutrophils. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[48]  J. Grünfeld,et al.  Atypical autoantigen targets of perinuclear antineutrophil cytoplasm antibodies (P-ANCA): specificity and clinical associations. , 1993, Journal of Autoimmunity.

[49]  E. Csernok,et al.  ANCA and associated diseases: immunodiagnostic and pathogenetic aspects , 1993, Clinical and experimental immunology.

[50]  R. Coombs,et al.  Viricidal effect of polymorphonuclear leukocytes on human immunodeficiency virus-1. Role of the myeloperoxidase system. , 1992, The Journal of clinical investigation.

[51]  M. Steens,et al.  Lethal oxidative damage to human immunodeficiency virus by human recombinant myeloperoxidase , 1992, FEBS letters.

[52]  S. Kobayashi,et al.  Purification of the active C5a receptor from human polymorphonuclear leukocytes as a receptor-Gi complex. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[53]  M. Springer,et al.  Interaction between the C5a receptor and Gi in both the membrane-bound and detergent-solubilized states. , 1990, The Journal of biological chemistry.

[54]  A. Kondo,et al.  Separation of Murine Neutrophils and Macrophages by Thermoresponsive Magnetic Nanoparticles , 2007, Biotechnology progress.

[55]  B. Neel,et al.  FcgammaRIII-dependent inhibition of interferon-gamma responses mediates suppressive effects of intravenous immune globulin. , 2007, Immunity.

[56]  S. Akira,et al.  Dectin-1 is required for host defense against Pneumocystis carinii but not against Candida albicans , 2007, Nature Immunology.

[57]  S. Gordon,et al.  Dectin-1 is required for beta-glucan recognition and control of fungal infection. , 2007, Nature immunology.

[58]  B. Neel,et al.  FcγRIII-Dependent Inhibition of Interferon-γ Responses Mediates Suppressive Effects of Intravenous Immune Globulin , 2007 .

[59]  R. Kastelein,et al.  Understanding the IL-23-IL-17 immune pathway. , 2006, Trends in immunology.