Water control mechanism of byakkokaninjinto and its active components via aquaporins

Byakkokaninjinto (BKN) is clinically used for conditions associated with thirst, polyuria, or cutaneous pruritus. Recently, it has also been used for improving thirst and polyuria observed in diabetes as well as pruritus associated with excessively dry skin. The aim of this study was to investigate aquaporins (AQP) in order to obtain scientific evidence regarding the mechanisms of BKN's effect.

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