Control of autophagy by oncogenes and tumor suppressor genes
暂无分享,去创建一个
[1] D. Stolz,et al. Involvement of Protective Autophagy in TRAIL Resistance of Apoptosis-defective Tumor Cells* , 2008, Journal of Biological Chemistry.
[2] Guido Kroemer,et al. Tumor cell metabolism: cancer's Achilles' heel. , 2008, Cancer cell.
[3] B. Arun,et al. Silencing of Bcl-2 expression by small interfering RNA induces autophagic cell death in MCF-7 breast cancer cells , 2008, Autophagy.
[4] Nektarios Tavernarakis,et al. Regulation of autophagy by cytoplasmic p53 , 2008, Nature Cell Biology.
[5] G. Semenza,et al. Mitochondrial Autophagy Is an HIF-1-dependent Adaptive Metabolic Response to Hypoxia* , 2008, Journal of Biological Chemistry.
[6] T. Hupp,et al. DAPK-1 Binding to a Linear Peptide Motif in MAP1B Stimulates Autophagy and Membrane Blebbing* , 2008, Journal of Biological Chemistry.
[7] A. Apel,et al. Blocked autophagy sensitizes resistant carcinoma cells to radiation therapy. , 2008, Cancer research.
[8] Lorenzo Galluzzi,et al. To die or not to die: that is the autophagic question. , 2008, Current molecular medicine.
[9] J. Ryerse,et al. BH3-only protein BIK induces caspase-independent cell death with autophagic features in Bcl-2 null cells , 2008, Oncogene.
[10] A. Letai,et al. Diagnosing and exploiting cancer's addiction to blocks in apoptosis , 2008, Nature Reviews Cancer.
[11] T. Vellai,et al. Longevity pathways converge on autophagy genes to regulate life span in Caenorhabditis elegans , 2008, Autophagy.
[12] W. Gu,et al. p53-Dependent and p53-independent activation of autophagy by ARF. , 2008, Cancer research.
[13] G. Gao,et al. Autophagy protects LNCaP cells under androgen deprivation conditions , 2008, Autophagy.
[14] J. Debnath,et al. Induction of autophagy during extracellular matrix detachment promotes cell survival. , 2007, Molecular biology of the cell.
[15] Ashok Kumar,et al. Inhibition of N-(4-hydroxyphenyl)retinamide-induced autophagy at a lower dose enhances cell death in malignant glioma cells. , 2007, Carcinogenesis.
[16] L. Zitvogel,et al. Immunological aspects of cancer chemotherapy , 2008, Nature Reviews Immunology.
[17] S. Gorski,et al. Macroautophagy inhibition sensitizes tamoxifen-resistant breast cancer cells and enhances mitochondrial depolarization , 2008, Breast Cancer Research and Treatment.
[18] C. Thompson,et al. The Roles of Therapy-Induced Autophagy and Necrosis in Cancer Treatment , 2007, Clinical Cancer Research.
[19] J. Opferman,et al. NIX is required for programmed mitochondrial clearance during reticulocyte maturation , 2007, Proceedings of the National Academy of Sciences.
[20] Robin Mathew,et al. Role of autophagy in cancer , 2007, Nature Reviews Cancer.
[21] Y. Atomi,et al. Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation. , 2007, Cancer research.
[22] J. J. Mul,et al. Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis , 2007, Nature Cell Biology.
[23] Hao Wu,et al. Molecular basis of Bcl-xL's target recognition versatility revealed by the structure of Bcl-xL in complex with the BH3 domain of Beclin-1. , 2007, Journal of molecular biology.
[24] Guido Kroemer,et al. Self-eating and self-killing: crosstalk between autophagy and apoptosis , 2007, Nature Reviews Molecular Cell Biology.
[25] D. Neil Hayes,et al. LKB1 modulates lung cancer differentiation and metastasis , 2007, Nature.
[26] R. Schwartz,et al. Tuberous sclerosis complex: advances in diagnosis, genetics, and management. , 2007, Journal of the American Academy of Dermatology.
[27] Liat Mizrachy,et al. Differential Interactions Between Beclin 1 and Bcl-2 Family Members , 2007, Autophagy.
[28] E. White,et al. Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis. , 2007, Genes & development.
[29] Peter Schwartz,et al. Ambra1 regulates autophagy and development of the nervous system , 2007, Nature.
[30] C. López-Otín,et al. Tissue-specific Autophagy Alterations and Increased Tumorigenesis in Mice Deficient in Atg4C/Autophagin-3* , 2007, Journal of Biological Chemistry.
[31] E. White,et al. Autophagy suppresses tumor progression by limiting chromosomal instability. , 2007, Genes & development.
[32] Nektarios Tavernarakis,et al. Functional and physical interaction between Bcl‐XL and a BH3‐like domain in Beclin‐1 , 2007, The EMBO journal.
[33] Yigong Shi,et al. Crystal Structure of the Bcl-XL-Beclin 1 Peptide Complex , 2007, Journal of Biological Chemistry.
[34] B. Levine,et al. Cell biology: Autophagy and cancer , 2007, Nature.
[35] J. Vicencio,et al. BH3-Only Proteins and BH3 Mimetics Induce Autophagy by Competitively Disrupting the Interaction between Beclin 1 and Bcl-2/Bcl-XL , 2007, Autophagy.
[36] Karen H. Vousden,et al. p53 in health and disease , 2007, Nature Reviews Molecular Cell Biology.
[37] M. J. Abedin,et al. Autophagy delays apoptotic death in breast cancer cells following DNA damage , 2007, Cell Death and Differentiation.
[38] Per O. Seglen,et al. Methods for Monitoring Autophagy from Yeast to Human , 2007, Autophagy.
[39] Gordon B. Mills,et al. The energy sensing LKB1–AMPK pathway regulates p27kip1 phosphorylation mediating the decision to enter autophagy or apoptosis , 2007, Nature Cell Biology.
[40] G. Evan,et al. Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma. , 2007, The Journal of clinical investigation.
[41] C. Miracco,et al. Protein and mRNA expression of autophagy gene Beclin 1 in human brain tumours. , 2007, International journal of oncology.
[42] R. Gottlieb,et al. Response to myocardial ischemia/reperfusion injury involves Bnip3 and autophagy , 2007, Cell Death and Differentiation.
[43] Ileana M. Cristea,et al. Induction of Autophagy in Axonal Dystrophy and Degeneration , 2006, The Journal of Neuroscience.
[44] Kevin M. Ryan,et al. DRAM, a p53-Induced Modulator of Autophagy, Is Critical for Apoptosis , 2006, Cell.
[45] Kevin Bray,et al. Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis. , 2006, Cancer cell.
[46] B. Oh,et al. Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG , 2006, Nature Cell Biology.
[47] L. Cantley,et al. Ras, PI(3)K and mTOR signalling controls tumour cell growth , 2006, Nature.
[48] Tak W. Mak,et al. Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis , 2006, Nature Reviews Cancer.
[49] A. Kimchi,et al. DAPk Protein Family and Cancer , 2006, Autophagy.
[50] S. Rodríguez-Enríquez,et al. Tracker Dyes to Probe Mitochondrial Autophagy (Mitophagy) in Rat Hepatocytes , 2006, Autophagy.
[51] Guido Kroemer,et al. Lysosomes and autophagy in cell death control , 2005, Nature Reviews Cancer.
[52] Y. Tsujimoto,et al. Another way to die: autophagic programmed cell death , 2005, Cell Death and Differentiation.
[53] Michael D. Schneider,et al. Bcl-2 Antiapoptotic Proteins Inhibit Beclin 1-Dependent Autophagy , 2005, Cell.
[54] A. Levine,et al. The coordinate regulation of the p53 and mTOR pathways in cells. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[55] S. Korsmeyer,et al. An inhibitor of Bcl-2 family proteins induces regression of solid tumours , 2005, Nature.
[56] Philippe Dessen,et al. Inhibition of Macroautophagy Triggers Apoptosis , 2005, Molecular and Cellular Biology.
[57] Y. Kondo,et al. Pivotal Role of the Cell Death Factor BNIP3 in Ceramide-Induced Autophagic Cell Death in Malignant Glioma Cells , 2004, Cancer Research.
[58] Govind Bhagat,et al. Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene. , 2003, The Journal of clinical investigation.
[59] Arnold J. Levine,et al. Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[60] G. Kroemer,et al. Bcl-2 down-regulation causes autophagy in a caspase-independent manner in human leukemic HL60 cells , 2000, Cell Death and Differentiation.
[61] A. Levine,et al. Surfing the p53 network , 2000, Nature.
[62] D. Hanahan,et al. The Hallmarks of Cancer , 2000, Cell.
[63] J. Levine,et al. Surfing the p53 network , 2000, Nature.
[64] H. Hibshoosh,et al. Induction of autophagy and inhibition of tumorigenesis by beclin 1 , 1999, Nature.