A Retrospective Analysis of Inflammatory Factors in Adult Patients With Cutaneous Vasculitis

Background: Cutaneous vasculitis is defined as the inflammation of blood vessels of the dermis. However cutaneous vasculitis is not a specific disease but a manifestation that can be seen in a variety of settings. We sought to review the clinical manifestations, laboratorial findings, pathological changes and etiologic association of cutaneous vasculitis in patients admitted to Dermatology Department of Razi Hospital from 1998 to 2011. Materials and Methods: In this retrospective study, we enrolled all patients with records of histological diagnosis of vasculitis between 1998 and 2011 in Razi Hospital. Clinical presentation and inflammatory factors were evaluated, too.Results: We studied 56 patients with cutaneous vasculitis. 35 (62.5%) patients were female and 20 (37.5%) were male. About 75% of patients had hypersensitivity vasculitis, 10.6% Henoch-Schonlein purpura, 9% urticarial vasculitis, and 5.4% polyarteritis nodosa.Conclusion: It seems that hypersensitivity vasculitis is the most common form of cutaneous vasculitis. The main clinical manifestations of hypersensitivity vasculitis are skin and joint symptoms.

[1]  C. Sunderkötter,et al.  Clinical classification of vasculitis. , 2006, European journal of dermatology : EJD.

[2]  R A Watts,et al.  Evaluation of the Sørensen diagnostic criteria in the classification of systemic vasculitis. , 2002, Rheumatology.

[3]  J. Carlson,et al.  Clinical Approach to Cutaneous Vasculitis , 2008, American journal of clinical dermatology.

[4]  M. González-Gay,et al.  Clinical approach to cutaneous vasculitis , 2005, Current opinion in rheumatology.

[5]  R. Porter Nomenclature of Systemic Vasculitides: Proposal of an International Consensus Conference , 1995 .

[6]  J. Carlson,et al.  Cutaneous Vasculitis Update: Diagnostic Criteria, Classification, Epidemiology, Etiology, Pathogenesis, Evaluation and Prognosis , 2005, The American Journal of dermatopathology.

[7]  V. Rodríguez-Valverde,et al.  Cutaneous vasculitis in children and adults. Associated diseases and etiologic factors in 303 patients. , 1998 .

[8]  J. Stone,et al.  “Essential” cutaneous vasculitis: what every rheumatologist should know about vasculitis of the skin , 2001, Current opinion in rheumatology.

[9]  E. Condom,et al.  Prognostic factors in leukocytoclastic vasculitis: a clinicopathologic study of 160 patients. , 1998, Archives of dermatology.

[10]  C. Magro,et al.  Cutaneous vasculitis: a review , 2003, Journal of cutaneous pathology.

[11]  N. Al‐Mutairi Spectrum of Cutaneous Vasculitis in Adult Patients from the Farwaniya Region of Kuwait , 2007, Medical Principles and Practice.

[12]  J. Callen,et al.  Cutaneous leukocytoclastic vasculitis: correlation of histopathological changes with clinical severity and course , 1987, Journal of cutaneous pathology.

[13]  R. Kelly,et al.  Retrospective analysis of adult patients with cutaneous leukocytoclastic vasculitis , 2006, The Australasian journal of dermatology.