Keratin 8-deletion induced colitis predisposes to murine colorectal cancer enforced by the inflammasome and IL-22 pathway.
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Trine Husøy | Pekka Taimen | Adolfo Rivero-Müller | P. Taimen | T. Husøy | D. Toivola | Diana M Toivola | J. Nyström | A. Rivero-Müller | Josef Gullmets | Julia O Misiorek | Iris A K Lähdeniemi | Joel H Nyström | Valeriy M Paramonov | Josef A Gullmets | Helena Saarento | Valeriy M. Paramonov | Julia O. Misiorek | I. Lähdeniemi | Helena Saarento
[1] M. Omary,et al. Keratin 20 helps maintain intermediate filament organization in intestinal epithelia. , 2003, Molecular biology of the cell.
[2] H. Thompson,et al. A Method for Serial Tissue Processing and Parallel Analysis of Aberrant Crypt Morphology, Mucin Depletion, and Beta-Catenin Staining in an Experimental Model of Colon Carcinogenesis , 2010, Biological Procedures Online.
[3] K. Hung,et al. Molecular Mechanisms of Colorectal Carcinogenesis , 2013 .
[4] V. Karantza,et al. Keratins in health and cancer: more than mere epithelial cell markers , 2011, Oncogene.
[5] Francis J. Huber,et al. IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine , 2012, Nature.
[6] D. Kamp,et al. Vimentin regulates activation of the NLRP3 inflammasome , 2015, Nature Communications.
[7] Stefan Wirtz,et al. Chemically induced mouse models of intestinal inflammation , 2007, Nature Protocols.
[8] Bert Vogelstein,et al. APC mutations occur early during colorectal tumorigenesis , 1992, Nature.
[9] T. Magin,et al. Regulation of keratin network organization. , 2015, Current opinion in cell biology.
[10] IL-22 is related to development of human colon cancer by activation of STAT3 , 2013, BMC Cancer.
[11] P. Rutgeerts,et al. Unique Gene Expression and MR T2 Relaxometry Patterns Define Chronic Murine Dextran Sodium Sulphate Colitis as a Model for Connective Tissue Changes in Human Crohn’s Disease , 2013, PloS one.
[12] E. Lane,et al. Keratin mutations and intestinal pathology , 2004, The Journal of pathology.
[13] M. Parkes,et al. Human keratin 8 mutations that disturb filament assembly observed in inflammatory bowel disease patients , 2004, Journal of Cell Science.
[14] Judy H. Cho,et al. Analysis of keratin polypeptides 8 and 19 variants in inflammatory bowel disease. , 2007, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.
[15] P. Boor,et al. Keratins in health and disease. , 2015, Current opinion in cell biology.
[16] A. Takayanagi,et al. Interleukin-22, a member of the IL-10 subfamily, induces inflammatory responses in colonic subepithelial myofibroblasts. , 2005, Gastroenterology.
[17] T. P. Pretlow,et al. Aberrant crypt foci: what we know and what we need to know. , 2007, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.
[18] M. Omary,et al. Keratin 8 absence down-regulates colonocyte HMGCS2 and modulates colonic ketogenesis and energy metabolism , 2015, Molecular biology of the cell.
[19] M. Merad,et al. Interleukin-22 binding protein (IL-22BP) is constitutively expressed by a subset of conventional dendritic cells and is strongly induced by retinoic acid , 2013, Mucosal Immunology.
[20] I. Petersen,et al. Cytokeratin Profiles Identify Diagnostic Signatures in Colorectal Cancer Using Multiplex Analysis of Tissue Microarrays , 2006, Cellular oncology : the official journal of the International Society for Cellular Oncology.
[21] C. Alam,et al. The Amount of Keratins Matters for Stress Protection of the Colonic Epithelium , 2015, PloS one.
[22] T. Takayama,et al. Aberrant crypt foci: detection, gene abnormalities, and clinical usefulness. , 2005, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.
[23] P. Coulombe,et al. The expanding significance of keratin intermediate filaments in normal and diseased epithelia. , 2013, Current opinion in cell biology.
[24] Joachim L. Schultze,et al. Keratin 1 maintains skin integrity and participates in an inflammatory network in skin through interleukin-18 , 2012, Journal of Cell Science.
[25] M. Omary,et al. Keratin-8-deficient mice develop chronic spontaneous Th2 colitis amenable to antibiotic treatment , 2005, Journal of Cell Science.
[26] M. Silverberg,et al. Higher Activity of the Inducible Nitric Oxide Synthase Contributes to Very Early Onset Inflammatory Bowel Disease , 2014, Clinical and Translational Gastroenterology.
[27] Takuji Tanaka,et al. Dextran sodium sulfate strongly promotes colorectal carcinogenesis in ApcMin/+ mice: Inflammatory stimuli by dextran sodium sulfate results in development of multiple colonic neoplasms , 2006, International journal of cancer.
[28] S. Rutz,et al. Interleukin-22 induces interleukin-18 expression from epithelial cells during intestinal infection. , 2015, Immunity.
[29] H. Baribault,et al. Mid-gestational lethality in mice lacking keratin 8. , 1993, Genes & development.
[30] G. Barber,et al. Diverse roles of STING-dependent signaling on the development of cancer , 2015, Oncogene.
[31] Shengdi Hu,et al. An Efficient Genotyping Method for Genome-modified Animals and Human Cells Generated with CRISPR/Cas9 System , 2014, Scientific Reports.
[32] M. Omary,et al. Intermediate filaments take the heat as stress proteins. , 2010, Trends in cell biology.
[33] R. Iozzo,et al. Colorectal hyperplasia and inflammation in keratin 8-deficient FVB/N mice. , 1994, Genes & development.
[34] S. Cross,et al. Inflammation decreases keratin level in ulcerative colitis; inadequate restoration associates with increased risk of colitis-associated cancer , 2015, BMJ open gastroenterology.
[35] T. Magin,et al. Cytokines as genetic modifiers in K5–/– mice and in human epidermolysis bullosa simplex , 2009, Human mutation.
[36] R. Sabat,et al. Interleukin-22: a cytokine produced by T, NK and NKT cell subsets, with importance in the innate immune defense and tissue protection. , 2010, Cytokine & growth factor reviews.
[37] R Fodde,et al. A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[38] M. Lukáš. Inflammatory Bowel Disease as a Risk Factor for Colorectal Cancer , 2010, Digestive Diseases.
[39] H. Knutsen,et al. The min mouse on FVB background: susceptibility to spontaneous and carcinogen-induced intestinal tumourigenesis. , 2011, Anticancer research.
[40] Y. Dou,et al. IL-22(+)CD4(+) T cells promote colorectal cancer stemness via STAT3 transcription factor activation and induction of the methyltransferase DOT1L. , 2014, Immunity.
[41] M. Omary,et al. Toward unraveling the complexity of simple epithelial keratins in human disease. , 2009, The Journal of clinical investigation.
[42] W. Ouyang,et al. Deciphering the crosstalk among IL-1 and IL-10 family cytokines in intestinal immunity. , 2015, Trends in immunology.
[43] M. Neurath,et al. STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing , 2009, The Journal of experimental medicine.
[44] Satish K. Singh,et al. Keratins modulate colonocyte electrolyte transport via protein mistargeting , 2004, The Journal of cell biology.
[45] G. Duester. Families of retinoid dehydrogenases regulating vitamin A function: production of visual pigment and retinoic acid. , 2000, European journal of biochemistry.
[46] F. Powrie,et al. Innate lymphoid cells sustain colon cancer through production of interleukin-22 in a mouse model , 2013, The Journal of experimental medicine.
[47] R. Moll,et al. The human keratins: biology and pathology , 2008, Histochemistry and Cell Biology.
[48] M. Omary,et al. Absence of keratin 8 confers a paradoxical microflora-dependent resistance to apoptosis in the colon , 2011, Proceedings of the National Academy of Sciences.
[49] D. Hanahan,et al. Hallmarks of Cancer: The Next Generation , 2011, Cell.
[50] D. Haro,et al. Ketogenic HMGCS2 Is a c-Myc Target Gene Expressed in Differentiated Cells of Human Colonic Epithelium and Down-Regulated in Colon Cancer , 2006, Molecular Cancer Research.
[51] David A. Scott,et al. Genome engineering using the CRISPR-Cas9 system , 2013, Nature Protocols.
[52] D. Artis,et al. Border patrol: regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22 , 2011, Nature Immunology.
[53] C. Rao,et al. Adoptive transfer of regulatory T cells promotes intestinal tumorigenesis and is associated with decreased NK cells and IL‐22 binding protein , 2015, Molecular carcinogenesis.
[54] E. Mizoguchi,et al. Animal models of IBD: linkage to human disease. , 2010, Current opinion in pharmacology.
[55] Markus F Neurath,et al. An inducible mouse model of colon carcinogenesis for the analysis of sporadic and inflammation-driven tumor progression , 2007, Nature Protocols.
[56] I. Singer,et al. Cyclooxygenase 2 is induced in colonic epithelial cells in inflammatory bowel disease. , 1998, Gastroenterology.