Consequences of VHL Loss on Global DNA Methylome
暂无分享,去创建一个
M. Lathrop | William Y. Kim | F. Lefebvre | M. Ohh | Y. Riazalhosseini | J. Tost | Aurélie Bousard | Claire M. Robinson | Betty P. K. Poon | Xiaojun Fan
[1] Bram Boeckx,et al. Tumor hypoxia causes DNA hypermethylation by reducing TET activity , 2016, Nature.
[2] Rochelle L. Tiedemann,et al. Dynamic reprogramming of DNA methylation in SETD2-deregulated renal cell carcinoma , 2015, Oncotarget.
[3] K. Bensalah,et al. Identification and validation of TGFBI as a promising prognosis marker of clear cell renal cell carcinoma. , 2015, Urologic oncology.
[4] Raphael Gottardo,et al. Orchestrating high-throughput genomic analysis with Bioconductor , 2015, Nature Methods.
[5] Matthew E. Ritchie,et al. limma powers differential expression analyses for RNA-sequencing and microarray studies , 2015, Nucleic acids research.
[6] D. Schübeler. Function and information content of DNA methylation , 2015, Nature.
[7] Edgars Celms,et al. Variation in genomic landscape of clear cell renal cell carcinoma across Europe , 2014, Nature Communications.
[8] M. Ohh,et al. The multifaceted von Hippel–Lindau tumour suppressor protein , 2014, FEBS letters.
[9] R. Wenger,et al. TET1-Mediated Hydroxymethylation Facilitates Hypoxic Gene Induction in Neuroblastoma , 2014, Cell reports.
[10] Rafael A. Irizarry,et al. Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays , 2014, Bioinform..
[11] Ty C. Voss,et al. Dynamic regulation of transcriptional states by chromatin and transcription factors , 2013, Nature Reviews Genetics.
[12] The Cancer Genome Atlas Research Network. COMPREHENSIVE MOLECULAR CHARACTERIZATION OF CLEAR CELL RENAL CELL CARCINOMA , 2013, Nature.
[13] Steven J. M. Jones,et al. Comprehensive molecular characterization of clear cell renal cell carcinoma , 2013, Nature.
[14] Ivana Holcatova,et al. Integrative Genome-Wide Gene Expression Profiling of Clear Cell Renal Cell Carcinoma in Czech Republic and in the United States , 2013, PloS one.
[15] A. Viale,et al. Epigenetic expansion of VHL-HIF signal output drives multi-organ metastasis in renal cancer , 2012, Nature Medicine.
[16] A. Oshlack,et al. SWAN: Subset-quantile Within Array Normalization for Illumina Infinium HumanMethylation450 BeadChips , 2012, Genome Biology.
[17] Peter A. Jones. Functions of DNA methylation: islands, start sites, gene bodies and beyond , 2012, Nature Reviews Genetics.
[18] S. Weintraub,et al. The interaction of the von Hippel-Lindau tumor suppressor and heterochromatin protein 1. , 2012, Archives of biochemistry and biophysics.
[19] S. Baylin,et al. DNMT1 modulates gene expression without its catalytic activity partially through its interactions with histone-modifying enzymes , 2012, Nucleic acids research.
[20] S. Rocha,et al. Chromatin as an oxygen sensor and active player in the hypoxia response , 2012, Cellular signalling.
[21] Xiao Zhang,et al. Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis , 2010, BMC Bioinformatics.
[22] P. A. Futreal,et al. Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma , 2010, Nature.
[23] J. Ragoussis,et al. CpG methylation profiling in VHL related and VHL unrelated renal cell carcinoma , 2009, Molecular Cancer.
[24] Wei Li,et al. Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis , 2009, Proceedings of the National Academy of Sciences.
[25] P. Ratcliffe,et al. Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1alpha. , 2008, The Biochemical journal.
[26] Nicholas Denko,et al. Hypoxia induces a novel signature of chromatin modifications and global repression of transcription. , 2008, Mutation research.
[27] W. Kaelin. The von Hippel-Lindau Tumor Suppressor Protein and Clear Cell Renal Carcinoma , 2007, Clinical Cancer Research.
[28] H. Zentgraf,et al. The von Hippel-Lindau tumor suppressor protein controls ciliogenesis by orienting microtubule growth , 2006, The Journal of cell biology.
[29] S. Baylin,et al. DNA methylation and gene silencing in cancer , 2005, Nature Clinical Practice Oncology.
[30] G. Camenisch,et al. Integration of Oxygen Signaling at the Consensus HRE , 2005, Science's STKE.
[31] R. Kettmann,et al. Methylation of the CA9 promoter can modulate expression of the tumor-associated carbonic anhydrase IX in dense carcinoma cell lines. , 2005, International journal of oncology.
[32] W. Kaelin,et al. Role of VHL gene mutation in human cancer. , 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[33] R. Conaway,et al. von Hippel–Lindau protein binds hyperphosphorylated large subunit of RNA polymerase II through a proline hydroxylation motif and targets it for ubiquitination , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[34] N. Minato,et al. The von Hippel-Lindau Tumor Suppressor Protein Mediates Ubiquitination of Activated Atypical Protein Kinase C* , 2001, The Journal of Biological Chemistry.
[35] M. Ivan,et al. HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O2 Sensing , 2001, Science.
[36] M. Ivan,et al. Ubiquitination of hypoxia-inducible factor requires direct binding to the β-domain of the von Hippel–Lindau protein , 2000, Nature Cell Biology.
[37] C. Wykoff,et al. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis , 1999, Nature.
[38] M. Gassmann,et al. Oxygen-regulated erythropoietin gene expression is dependent on a CpG methylation-free hypoxia-inducible factor-1 DNA-binding site. , 1998, European journal of biochemistry.