The myeloid transcription factor KLF2 regulates the host response to polymicrobial infection and endotoxic shock.
暂无分享,去创建一个
Ross McManus | Saptarsi M. Haldar | Zhiyong Lin | Thomas Ryan | H. Wong | D. Jeyaraj | R. McManus | J. Lingrel | Y. Takami | P. Leahy | Ganapati H. Mahabeleshwar | G Brandon Atkins | Mukesh K. Jain | N. Sharma | Patrick Leahy | Guangjin Zhou | Daiji Kawanami | Hector R Wong | Mukesh K Jain | Darwin Jeyaraj | Nikunj Sharma | Ganapati H Mahabeleshwar | Hong Shi | Yoichi Takami | Zhiyong Lin | Guangjin Zhou | Hong Shi | G. Atkins | L. Nayak | Daiji Kawanami | Lalitha Nayak | Robert Grealy | Mary White | Saptarsi M Haldar | Jerry B Lingrel | R. Grealy | M. White | T. Ryan | M. Jain
[1] S. Jameson,et al. KLF2 transcription-factor deficiency in T cells results in unrestrained cytokine production and upregulation of bystander chemokine receptors. , 2009, Immunity.
[2] Zhuoxiao Cao,et al. Role of Kruppel-like factors in leukocyte development, function, and disease. , 2010, Blood.
[3] S. Krauss,et al. Signaling takes a breath--new quantitative perspectives on bioenergetics and signal transduction. , 2001, Immunity.
[4] V. Nizet,et al. HIF-1 regulates heritable variation and allele expression phenotypes of the macrophage immune response gene SLC11A1 from a Z-DNA forming microsatellite. , 2007, Blood.
[5] A. Liappis,et al. The effect of statins on mortality in patients with bacteremia. , 2001, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[6] Alternatively activated macrophage-derived RELM-α is a negative regulator of type 2 inflammation in the lung , 2009, The Journal of experimental medicine.
[7] E. Pamer,et al. Coordinating innate immune cells to optimize microbial killing. , 2008, Immunity.
[8] R. Jaenisch,et al. HIF-1α Is Essential for Myeloid Cell-Mediated Inflammation , 2003, Cell.
[9] R. Evans,et al. PPARδ regulates multiple proinflammatory pathways to suppress atherosclerosis , 2008, Proceedings of the National Academy of Sciences.
[10] S. Gordon,et al. Alternative activation of macrophages: an immunologic functional perspective. , 2009, Annual review of immunology.
[11] P. Loke. Faculty Opinions recommendation of Alternatively activated macrophage-derived RELM-{alpha} is a negative regulator of type 2 inflammation in the lung. , 2009 .
[12] R. Jain,et al. Kruppel-Like Factor 2 Inhibits Protease Activated Receptor-1 Expression and Thrombin-Mediated Endothelial Activation , 2006, Arteriosclerosis, thrombosis, and vascular biology.
[13] V. Nizet,et al. HIF-1alpha expression regulates the bactericidal capacity of phagocytes. , 2005, The Journal of clinical investigation.
[14] R. Khokha,et al. Tissue inhibitor of metalloproteinases 3 regulates resolution of inflammation following acute lung injury. , 2010, The American journal of pathology.
[15] W. Wiersinga,et al. Inflammation, endothelium, and coagulation in sepsis , 2008, Journal of leukocyte biology.
[16] Robin A. Weiss,et al. Infectogenomics: Insights from the Host Genome into Infectious Diseases , 2006, Cell.
[17] M. Rondaij,et al. KLF2 provokes a gene expression pattern that establishes functional quiescent differentiation of the endothelium. , 2006, Blood.
[18] J. Lingrel,et al. Isolation of a gene encoding a functional zinc finger protein homologous to erythroid Krüppel-like factor: identification of a new multigene family , 1995, Molecular and cellular biology.
[19] Ganapati H. Mahabeleshwar,et al. Kruppel-Like Factor 2 Regulates Endothelial Barrier Function , 2010, Arteriosclerosis, thrombosis, and vascular biology.
[20] P. Lepper. Faculty Opinions recommendation of Cutting edge: Essential role of hypoxia inducible factor-1alpha in development of lipopolysaccharide-induced sepsis. , 2007 .
[21] G. Atkins,et al. Role of Krüppel-like transcription factors in endothelial biology. , 2007, Circulation Research.
[22] Katerina Akassoglou,et al. NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α , 2008, Nature.
[23] M. Sitkovsky,et al. Model organisms: Animal Models of sepsis: setting the stage , 2005, Nature Reviews Drug Discovery.
[24] J. Kolls,et al. Cytokine-mediated regulation of antimicrobial proteins , 2008, Nature Reviews Immunology.
[25] C. Print,et al. Hypoxia-induced neutrophil survival is mediated by HIF-1α–dependent NF-κB activity , 2005, The Journal of experimental medicine.
[26] W. Aird. The role of the endothelium in severe sepsis and multiple organ dysfunction syndrome. , 2003, Blood.
[27] H. K. Bourns. Management of Sepsis , 1960, The Medical journal of the South-West.
[28] G. Garcı́a-Cardeña,et al. Kruppel-Like Factor 2 (KLF2) Regulates Endothelial Thrombotic Function , 2005, Circulation research.
[29] T. Hohl,et al. Monocyte-mediated defense against microbial pathogens. , 2008, Annual review of immunology.
[30] Robert J Freishtat,et al. BMC Medicine BioMed Central , 2009 .
[31] M. Gerstein,et al. RNA-Seq: a revolutionary tool for transcriptomics , 2009, Nature Reviews Genetics.
[32] J. Lingrel,et al. Kruppel-like factor 2 transcriptional regulation involves heterogeneous nuclear ribonucleoproteins and acetyltransferases. , 2005, Biochemistry.
[33] Caroline C. Blouin,et al. Hypoxic gene activation by lipopolysaccharide in macrophages: implication of hypoxia-inducible factor 1alpha. , 2004, Blood.
[34] D. Simon,et al. Hemizygous Deficiency of Krüppel-Like Factor 2 Augments Experimental Atherosclerosis , 2008, Circulation research.
[35] Deanna A. Mele,et al. Lymphocyte quiescence factor Dpp2 is transcriptionally activated by KLF2 and TOB1. , 2008, Molecular immunology.
[36] R. Munford. Severe sepsis and septic shock: the role of gram-negative bacteremia. , 2006, Annual review of pathology.
[37] R. Jaenisch,et al. HIF-1alpha is essential for myeloid cell-mediated inflammation. , 2003, Cell.
[38] Saptarsi M. Haldar,et al. Kruppel-like Factor 2 Inhibits Hypoxia-inducible Factor 1α Expression and Function in the Endothelium* , 2009, The Journal of Biological Chemistry.
[39] S. Gordon,et al. Alternative activation of macrophages: mechanism and functions. , 2010, Immunity.
[40] Mechanism of Hypoxia-Induced NF-κB , 2010, Molecular and Cellular Biology.
[41] F. Luscinskas,et al. KLF2 Is a Novel Transcriptional Regulator of Endothelial Proinflammatory Activation , 2004, The Journal of experimental medicine.
[42] V. Nizet,et al. Interdependence of hypoxic and innate immune responses , 2009, Nature Reviews Immunology.
[43] Anne F. Buckley,et al. Transcription factor LKLF is sufficient to program T cell quiescence via a c-Myc–dependent pathway , 2001, Nature Immunology.
[44] A. Monks,et al. Echinomycin, a small-molecule inhibitor of hypoxia-inducible factor-1 DNA-binding activity. , 2005, Cancer research.
[45] D. Rittirsch,et al. Immunodesign of experimental sepsis by cecal ligation and puncture , 2008, Nature Protocols.
[46] Mukesh K. Jain,et al. Tumor Necrosis Factor Alpha-Mediated Reduction of KLF2 Is Due to Inhibition of MEF2 by NF-κB and Histone Deacetylases , 2005, Molecular and Cellular Biology.
[47] P. Majumder,et al. Kruppel-like factor 2 (KLF2) regulates proinflammatory activation of monocytes. , 2006, Proceedings of the National Academy of Sciences of the United States of America.