Parameter Estimation and Prediction of COVID-19 Epidemic Turning Point and Ending Time of a Case Study on SIR/SQAIR Epidemic Models

In this paper, the SIR epidemiological model for the COVID-19 with unknown parameters is considered in the first strategy. Three curves (S, I, and R) are fitted to the real data of South Korea, based on a detailed analysis of the actual data of South Korea, taken from the Korea Disease Control and Prevention Agency (KDCA). Using the least square method and minimizing the error between the fitted curve and the actual data, unknown parameters, like the transmission rate, recovery rate, and mortality rate, are estimated. The goodness of fit model is investigated with two criteria (SSE and RMSE), and the uncertainty range of the estimated parameters is also presented. Also, using the obtained determined model, the possible ending time and the turning point of the COVID-19 outbreak in the United States are predicted. Due to the lack of treatment and vaccine, in the next strategy, a new group called quarantined people is added to the proposed model. Also, a hidden state, including asymptomatic individuals, which is very common in COVID-19, is considered to make the model more realistic and closer to the real world. Then, the SIR model is developed into the SQAIR model. The delay in the recovery of the infected person is also considered as an unknown parameter. Like the previous steps, the possible ending time and the turning point in the United States are predicted. The model obtained in each strategy for South Korea is compared with the actual data from KDCA to prove the accuracy of the estimation of the parameters.

[1]  Nuno Fernandes,et al.  Economic Effects of Coronavirus Outbreak (COVID-19) on the World Economy , 2020, SSRN Electronic Journal.

[2]  M. Shafiee,et al.  Estimation of Space and Time Shifts in Continuous 2-D Systems Using Instrumental Variable , 2014, Canadian Journal of Electrical and Computer Engineering.

[3]  A. Ahmadi,et al.  Modeling and forecasting trend of COVID-19 epidemic in Iran until May 13, 2020 , 2020, Medical journal of the Islamic Republic of Iran.

[4]  J. M. Gomes,et al.  Characterization of the COVID-19 pandemic and the impact of uncertainties, mitigation strategies, and underreporting of cases in South Korea, Italy, and Brazil , 2020, Chaos, Solitons & Fractals.

[5]  Liangrong Peng,et al.  Epidemic analysis of COVID-19 in China by dynamical modeling , 2020, medRxiv.

[6]  D. Patnaik,et al.  Estimating the parameters of susceptible-infected-recovered model of COVID-19 cases in India during lockdown periods , 2020, Chaos, Solitons & Fractals.

[7]  Mehrdad Abedi,et al.  Recursive Identification of Continuous Two-Dimensional Systems in the Presence of Additive Colored Noise , 2014 .

[8]  Asier Ibeas,et al.  Stability analysis and observer design for discrete-time SEIR epidemic models , 2015 .

[9]  Kok Yew Ng,et al.  COVID-19: Development of a robust mathematical model and simulation package with consideration for ageing population and time delay for control action and resusceptibility , 2020, Physica D: Nonlinear Phenomena.

[10]  G. Webb,et al.  Identifying the number of unreported cases in SIR epidemic models. , 2020, Mathematical medicine and biology : a journal of the IMA.

[11]  Asier Ibeas,et al.  Optimal Control Design of Impulsive SQEIAR Epidemic Models with Application to COVID-19 , 2020, Chaos, Solitons & Fractals.

[12]  D. O. Cajueiro,et al.  Modeling and forecasting the Covid-19 pandemic in Brazil , 2020, 2003.14288.

[13]  Behzad Ghanbari,et al.  On forecasting the spread of the COVID-19 in Iran: The second wave , 2020, Chaos, Solitons & Fractals.

[14]  G. Gaeta A simple SIR model with a large set of asymptomatic infectives , 2020, Mathematics in Engineering.

[15]  K. Hadeler PARAMETER ESTIMATION IN EPIDEMIC MODELS : SIMPLIFIED FORMULAS , 2012 .

[16]  Denis Efimov,et al.  Estimating the infection rate of a SIR epidemic model via differential elimination , 2019, 2019 18th European Control Conference (ECC).

[17]  Asier Ibeas,et al.  Observer-Based Adaptive PI Sliding Mode Control of Developed Uncertain SEIAR Influenza Epidemic Model Considering Dynamic Population. , 2019, Journal of theoretical biology.

[18]  G. Chowell,et al.  Transmission potential and severity of COVID-19 in South Korea , 2020, International Journal of Infectious Diseases.

[19]  G. Webb,et al.  Understanding Unreported Cases in the COVID-19 Epidemic Outbreak in Wuhan, China, and the Importance of Major Public Health Interventions , 2020, Biology.