Molecular Evolution of the Binding Site of the Acetylcholine Receptor a

[1]  Z. Vogel,et al.  How the mongoose can fight the snake: the binding site of the mongoose acetylcholine receptor. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[2]  J. Changeux,et al.  Functional architecture of the nicotinic acetylcholine receptor: from electric organ to brain. , 1991, Annual review of pharmacology and toxicology.

[3]  D. Bertrand,et al.  A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by α-BTX , 1990, Neuron.

[4]  J. Gershoni,et al.  Comparison of the toxin binding sites of the nicotinic acetylcholine receptor from Drosophila to human. , 1990, Biochemistry.

[5]  P. Whiting,et al.  Brain α-bungarotoxin binding protein cDNAs and MAbs reveal subtypes of this branch of the ligand-gated ion channel gene superfamily , 1990, Neuron.

[6]  S. Fuchs,et al.  Snake acetylcholine receptor: cloning of the domain containing the four extracellular cysteines of the alpha subunit. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[7]  P. Taylor,et al.  An analog of lophotoxin reacts covalently with Tyr190 in the alpha-subunit of the nicotinic acetylcholine receptor. , 1989, The Journal of biological chemistry.

[8]  T. Lentz,et al.  Binding of alpha-bungarotoxin to synthetic peptides corresponding to residues 173-204 of the alpha subunit of Torpedo, calf, and human acetylcholine receptor and restoration of high-affinity binding by sodium dodecyl sulfate. , 1988, Biochemistry.

[9]  J. Changeux,et al.  Amino acids of the Torpedo marmorata acetylcholine receptor alpha subunit labeled by a photoaffinity ligand for the acetylcholine binding site. , 1988, Biochemistry.

[10]  R. Longhi,et al.  The binding site for α-bungarotoxin resides in the sequence 188–201 of the α-subunit of acetylcholine receptor: Structure, conformation and binding characteristics of peptide [Lys] 188–201 , 1987, Neuroscience Letters.

[11]  J. Gershoni,et al.  Synthetic Peptides and Their Antibodies in the Analysis of the Acetylcholine Receptor a , 1987, Annals of the New York Academy of Sciences.

[12]  Z. Vogel,et al.  Species specificity of anti-acetylcholine receptor antibodies elicited by synthetic peptides. , 1987, Biochemistry.

[13]  J. Gershoni Expression of the alpha-bungarotoxin binding site of the nicotinic acetylcholine receptor by Escherichia coli transformants. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[14]  A. Mauron,et al.  Mapping the main immunogenic region and toxin-binding site of the nicotinic acetylcholine receptor. , 1987, Science.

[15]  S. Fuchs,et al.  Analysis of ligand binding to the synthetic dodecapeptide 185-196 of the acetylcholine receptor alpha subunit. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[16]  E. Dreyer,et al.  Location of ligand-binding sites on the nicotinic acetylcholine receptor alpha-subunit. , 1986, The Journal of biological chemistry.

[17]  J. Gershoni,et al.  Mapping of the alpha-bungarotoxin binding site within the alpha subunit of the acetylcholine receptor. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[18]  M. Atassi,et al.  Segment α 182‐198 of Torpedo californica acetylcholine receptor contains a second toxin‐binding region and binds anti‐receptor antibodies , 1986, FEBS letters.

[19]  S. Heinemann,et al.  Isolation of a cDNA clone coding for a possible neural nicotinic acetylcholine receptor α-subunit , 1986, Nature.

[20]  E. Hawrot,et al.  Determination of the primary amino acid sequence specifying the alpha-bungarotoxin binding site on the alpha subunit of the acetylcholine receptor from Torpedo californica. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[21]  S. Heinemann,et al.  Isolation of a clone coding for the alpha-subunit of a mouse acetylcholine receptor , 1985, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[22]  J. Gershoni,et al.  Antibodies to synthetic peptides as probes for the binding site on the alpha subunit of the acetylcholine receptor. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[23]  M. Mishina,et al.  Location of functional regions of acetylcholine receptor α-subunit by site-directed mutagenesis , 1985, Nature.

[24]  A. Dwork,et al.  Identification of the alpha subunit half-cystine specifically labeled by an affinity reagent for the acetylcholine receptor binding site. , 1984, The Journal of biological chemistry.

[25]  J P Changeux,et al.  Acetylcholine receptor: an allosteric protein. , 1984, Science.

[26]  J. Gershoni,et al.  Binding of alpha-bungarotoxin to isolated alpha subunit of the acetylcholine receptor of Torpedo californica: quantitative analysis with protein blots. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[27]  D. Mochly‐Rosen,et al.  Interaction of monoclonal antibodies to torpedo acetylcholine receptor with the receptor of skeletal muscle , 1983, Muscle & nerve.

[28]  J. Changeux,et al.  Complete mRNA coding sequence of the acetylcholine binding alpha-subunit of Torpedo marmorata acetylcholine receptor: a model for the transmembrane organization of the polypeptide chain. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[29]  S. Heinemann,et al.  Nucleotide and deduced amino acid sequences of Torpedo californica acetylcholine receptor gamma subunit. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[30]  T. Hirose,et al.  Cloning and sequence analysis of calf cDNA and human genomic DNA encoding α-subunit precursor of muscle acetylcholine receptor , 1983, Nature.

[31]  Takashi Miyata,et al.  Primary structure of α-subunit precursor of Torpedo californica acetylcholine receptor deduced from cDNA sequence , 1982, Nature.

[32]  M. Raftery,et al.  The nicotinic cholinergic receptor: correlation of molecular structure with functional properties. , 1982, Annual review of biochemistry.

[33]  D. Mochly‐Rosen,et al.  Monoclonal anti-acetylcholine-receptor antibodies directed against the cholinergic binding site. , 1981, Biochemistry.

[34]  S. Froehner,et al.  Restoration of 125I-alpha-bungarotoxin binding activity to the alpha subunit of Torpedo acetylcholine receptor isolated by gel electrophoresis in sodium dodecyl sulfate. , 1981, The Journal of biological chemistry.

[35]  J. Patrick,et al.  alpha-Bungarotoxin binding and cholinergic receptor function on a rat sympathetic nerve line. , 1977, The Journal of biological chemistry.

[36]  S. Fuchs,et al.  Immunological characterization of an irreversibly denatured acetylcholine receptor , 1977, FEBS letters.

[37]  E. Kochva,et al.  Neutralization of Viperidae and Elapidae snake venoms by sera of different animals. , 1977, Toxicon : official journal of the International Society on Toxinology.

[38]  H. C. Hartzell,et al.  Acetylcholine receptors at neuromuscular synapses: phylogenetic differences detected by snake alpha-neurotoxins. , 1975, Proceedings of the National Academy of Sciences of the United States of America.