Ethical principles governing research in child and adolescent psychiatry.

This paper examines the ethical principles governing research in child and adolescent psychiatry. The guidelines for protection of children and adolescents are research subjects are discussed. These include the principle of nonmaleficence and beneficence (the risk-benefit ratio), the principle of autonomy (informed consent and confidentiality), and the principle of justice (fair distribution of benefits and burdens of research). In the light of recent national efforts to help promote responsible research practice, the ethical standards relating to the protection of scientific integrity as well as research advocacy, training, and stewardship are also discussed.

[1]  T. Beauchamp,et al.  Principles of biomedical ethics , 1991 .

[2]  J. Lantos,et al.  Extracorporeal membrane oxygenation and the ethics of clinical research in pediatrics. , 1990, The New England journal of medicine.

[3]  S. E. Lind,et al.  Finder's fees for research subjects. , 1990, The New England journal of medicine.

[4]  A. Relman.  New "Information for Authors"--and readers. , 1990, The New England journal of medicine.

[5]  S. Benatar.  Academic Freedom in South Africa , 1990, Nature.

[6]  Drummond Rennie,et al.  Editorial Peer Review in Biomedical Publication: The First International Congress , 1990 .

[7]  A. Flanagin,et al.  New requirements for authors: signed statements of authorship responsibility and financial disclosure. , 1989, JAMA.

[8]  M. Barry.  Ethical considerations of human investigation in developing countries: the AIDS dilemma. , 1988, The New England journal of medicine.

[9]  M. Angell.  Ethical imperialism? Ethics in international collaborative clinical research. , 1988, The New England journal of medicine.

[10]  A. Trivelpiece.  Influencing congress: ten commandments. , 1988, Science.

[11]  J. Maddox.  Why the pressure to publish? , 1988, Nature.

[12]  P S Appelbaum,et al.  False hopes and best data: consent to research and the therapeutic misconception. , 1987, The Hastings Center report.

[13]  A. Holder.  When Researchers Are Served Subpoenas , 1985 .

[14]  A. Holder.  When researchers are served subpoenas: case study. , 1985, IRB.

[15]  M. Angell.  Patients' preferences in randomized clinical trials. , 1984, The New England journal of medicine.

[16]  J. Rawls,et al.  John Rawls: A Theory of Justice , 1973 .

[17]  B. Gandevia,et al.  DECLARATION OF HELSINKI , 1964, Definitions.

[18]  Rickham Pp.  Human Experimentation: Code of Ethics of the World Medical Association (Declaration of Helsinki). , 1964, Canadian Medical Association journal.

[19]  P. W. Bowman,et al.  PHS Public Health Service , 1963 .

[20]  James M. Orten,et al.  Trials of War Criminals Before the Nuremberg Military Tribunals , 1950 .

[21]  Peter D. Feaver,et al.  Guarding the guardians , 1992 .

[22]  M. Rutter,et al.  Assessment and Diagnosis in Child Psychopathology , 1988 .

[23]  A. Costello,et al.  Structured psychiatric interviews for children. , 1988 .

[24]  P. Greene,et al.  Policies for responding to allegations of fraud in research , 1985, Minerva.

[25]  David Hume.  A Treatise of Human Nature: Being an Attempt to introduce the experimental Method of Reasoning into Moral Subjects , 1972 .